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Volumn 82, Issue 4, 2006, Pages 527-533

Methotrexate-albumin and aminopterin-albumin effectively prevent experimental acute graft-versus-host disease

Author keywords

Allogeneic stem cell transplantation; Aminopterin albumin; Graft versus host disease; Human serum albumin; Methotrexate albumin

Indexed keywords

AMINOPTERIN ALBUMIN CONJUGATE; CYTOTOXIC AGENT; METHOTREXATE ALBUMIN CONJUGATE; UNCLASSIFIED DRUG;

EID: 33747889199     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000229451.40286.64     Document Type: Article
Times cited : (8)

References (32)
  • 1
    • 0344925935 scopus 로고    scopus 로고
    • Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation
    • IBMTR Histocompatibility and Stem Cell Sources Working Committee and the European Group for Blood and Marrow Transplantation (EBMT)
    • Champlin RE, Schmitz N, Horowitz MM, et al. Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation. IBMTR Histocompatibility and Stem Cell Sources Working Committee and the European Group for Blood and Marrow Transplantation (EBMT). Blood 2000; 95: 3702.
    • (2000) Blood , vol.95 , pp. 3702
    • Champlin, R.E.1    Schmitz, N.2    Horowitz, M.M.3
  • 2
    • 0002058229 scopus 로고    scopus 로고
    • Uses and Growth of Hematopoietic Cell Transplantation
    • Thomas ED BKFSe, ed. Boston: Blackwell Science
    • Horowitz MM. Uses and Growth of Hematopoietic Cell Transplantation. In: Thomas ED BKFSe, ed. Hematopoietic Stem Cell Transplantation. Boston: Blackwell Science, 1999: 12.
    • (1999) Hematopoietic Stem Cell Transplantation , pp. 12
    • Horowitz, M.M.1
  • 3
    • 0026652486 scopus 로고
    • Long-term follow-up of a controlled trial comparing a combination of methotrexate plus cyclosporine with cyclosporine alone for prophylaxis of graft-versus-host disease in patients administered HLA-identical marrow grafts for leukemia
    • Storb R, Pepe M, Deeg HJ, et al. Long-term follow-up of a controlled trial comparing a combination of methotrexate plus cyclosporine with cyclosporine alone for prophylaxis of graft-versus-host disease in patients administered HLA-identical marrow grafts for leukemia. Blood 1992; 80: 560.
    • (1992) Blood , vol.80 , pp. 560
    • Storb, R.1    Pepe, M.2    Deeg, H.J.3
  • 4
    • 0026537653 scopus 로고
    • Decreased incidence of graft-versus-host disease and improved survival with methotrexate combined with cyclosporin compared with monotherapy in recipients of bone marrow from donors other than HLA identical siblings
    • Ringden O, Klaesson S, Sundberg B, et al. Decreased incidence of graft-versus-host disease and improved survival with methotrexate combined with cyclosporin compared with monotherapy in recipients of bone marrow from donors other than HLA identical siblings. Bone Marrow Transplant 1992; 9: 19.
    • (1992) Bone Marrow Transplant , vol.9 , pp. 19
    • Ringden, O.1    Klaesson, S.2    Sundberg, B.3
  • 5
    • 0024510510 scopus 로고
    • Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: Long-term follow-up of a controlled trial
    • Storb R, Deeg HJ, Pepe M, et al. Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial. Blood 1989; 73: 1729.
    • (1989) Blood , vol.73 , pp. 1729
    • Storb, R.1    Deeg, H.J.2    Pepe, M.3
  • 7
    • 5044252176 scopus 로고    scopus 로고
    • A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation
    • Bolwell B, Sobecks R, Pohlman B, et al. A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation. Bone Marrow Transplant 2004; 34: 621.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 621
    • Bolwell, B.1    Sobecks, R.2    Pohlman, B.3
  • 8
    • 0032904067 scopus 로고    scopus 로고
    • Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients
    • Phase I Study Group of the Association for Medical Oncology of the German Cancer Society
    • Hartung G, Stehle G, Sinn H, et al. Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Phase I Study Group of the Association for Medical Oncology of the German Cancer Society. Clin Cancer Res 1999; 5: 753.
    • (1999) Clin Cancer Res , vol.5 , pp. 753
    • Hartung, G.1    Stehle, G.2    Sinn, H.3
  • 9
    • 0036201980 scopus 로고    scopus 로고
    • A phase II trial of methotrexate-human serum albumin (MTX-HSA) in patients with metastatic renal cell carcinoma who progressed under immunotherapy
    • Vis N, van der GA, van Rhijn G, et al. A phase II trial of methotrexate-human serum albumin (MTX-HSA) in patients with metastatic renal cell carcinoma who progressed under immunotherapy. Cancer Chemother Pharmacol 2002; 49: 342.
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 342
    • Vis, N.1    Van Der, G.A.2    Van Rhijn, G.3
  • 10
    • 0030842545 scopus 로고    scopus 로고
    • Plasma protein (albumin) catabolism by the tumor itself-implications for tumor metabolism and the genesis of cachexia
    • Stehle G, Sinn H, Wunder A, et al. Plasma protein (albumin) catabolism by the tumor itself-implications for tumor metabolism and the genesis of cachexia. Crit Rev Oncol Hematol 1997; 26: 77.
    • (1997) Crit Rev Oncol Hematol , vol.26 , pp. 77
    • Stehle, G.1    Sinn, H.2    Wunder, A.3
  • 11
    • 0242416983 scopus 로고    scopus 로고
    • Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis
    • Wunder A, Muller-Ladner U, Stelzer EH, et al. Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis. J Immunol 2003; 170: 4793.
    • (2003) J Immunol , vol.170 , pp. 4793
    • Wunder, A.1    Muller-Ladner, U.2    Stelzer, E.H.3
  • 12
    • 4544254643 scopus 로고    scopus 로고
    • Albumin-coupled methotrexate (MTX-HSA) is a new anti-arthritic drug which acts synergistically to MTX
    • Fiehn C, Muller-Ladner U, Gay S, et al. Albumin-coupled methotrexate (MTX-HSA) is a new anti-arthritic drug which acts synergistically to MTX. Rheumatology (Oxford) 2004; 43: 1097.
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 1097
    • Fiehn, C.1    Muller-Ladner, U.2    Gay, S.3
  • 13
    • 18744407558 scopus 로고    scopus 로고
    • Mode of action of methotrexate-albumin in a human T-cell leukemia line and activity against an MTX-resistant clone
    • Weigand M, Hartung G, Roboz J, et al. Mode of action of methotrexate-albumin in a human T-cell leukemia line and activity against an MTX-resistant clone. Anticancer Drug Des 2001; 16: 227.
    • (2001) Anticancer Drug Des , vol.16 , pp. 227
    • Weigand, M.1    Hartung, G.2    Roboz, J.3
  • 14
    • 0038327602 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells
    • Wosikowski K, Biedermann E, Rattel B, et al. In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells. Clin Cancer Res 2003; 9: 1917.
    • (2003) Clin Cancer Res , vol.9 , pp. 1917
    • Wosikowski, K.1    Biedermann, E.2    Rattel, B.3
  • 15
    • 0030766390 scopus 로고    scopus 로고
    • The loading rate determines tumor targeting properties of methotrexate- Albumin conjugates in rats
    • Stehle G, Sinn H, Wunder A, et al. The loading rate determines tumor targeting properties of methotrexate- albumin conjugates in rats. Anticancer Drugs 1997; 8: 677.
    • (1997) Anticancer Drugs , vol.8 , pp. 677
    • Stehle, G.1    Sinn, H.2    Wunder, A.3
  • 16
    • 0030659779 scopus 로고    scopus 로고
    • Pharmacokinetics of methotrexate-albumin conjugates in tumor-bearing rats
    • Stehle G, Wunder A, Sinn H, et al. Pharmacokinetics of methotrexate-albumin conjugates in tumor-bearing rats. Anticancer Drugs 1997; 8: 835.
    • (1997) Anticancer Drugs , vol.8 , pp. 835
    • Stehle, G.1    Wunder, A.2    Sinn, H.3
  • 17
    • 0035371902 scopus 로고    scopus 로고
    • Pre-clinical evaluation of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts in vivo
    • Burger AM, Hartung G, Stehle G, et al. Pre-clinical evaluation of a methotrexate-albumin conjugate (MTX-HSA) in human tumor xenografts in vivo. Int J Cancer 2001; 92: 718.
    • (2001) Int J Cancer , vol.92 , pp. 718
    • Burger, A.M.1    Hartung, G.2    Stehle, G.3
  • 18
    • 0033112951 scopus 로고    scopus 로고
    • Methotrexate-albumin conjugate causes tumor growth delay in Dunning R3327 HI prostate cancer-bearing rats
    • Stehle G, Wunder A, Schrenk HH, et al. Methotrexate-albumin conjugate causes tumor growth delay in Dunning R3327 HI prostate cancer-bearing rats. Anticancer Drugs 1999; 10: 405.
    • (1999) Anticancer Drugs , vol.10 , pp. 405
    • Stehle, G.1    Wunder, A.2    Schrenk, H.H.3
  • 19
    • 0032503593 scopus 로고    scopus 로고
    • Antitumor activity of methotrexate-albumin conjugates in rats bearing a Walker-256 carcinoma
    • Wunder A, Stehle G, Schrenk HH, et al. Antitumor activity of methotrexate-albumin conjugates in rats bearing a Walker-256 carcinoma. Int J Cancer 1998; 76: 884.
    • (1998) Int J Cancer , vol.76 , pp. 884
    • Wunder, A.1    Stehle, G.2    Schrenk, H.H.3
  • 20
    • 3042698264 scopus 로고    scopus 로고
    • Methotrexate (MTX) and albumin coupled with MTX (MTX-HSA) suppress synovial fibroblast invasion and cartilage degradation in vivo
    • Fiehn C, Neumann E, Wunder A, et al. Methotrexate (MTX) and albumin coupled with MTX (MTX-HSA) suppress synovial fibroblast invasion and cartilage degradation in vivo. Ann Rheum Dis 2004; 63: 884.
    • (2004) Ann Rheum Dis , vol.63 , pp. 884
    • Fiehn, C.1    Neumann, E.2    Wunder, A.3
  • 21
    • 1642317926 scopus 로고    scopus 로고
    • Alloreactive CD4 T lymphocytes responsible for acute and chronic graft-versus-host disease are contained within the CD45RChigh but not the CD45RClow subset
    • Xystrakis E, Bernard I, Dejean AS, et al. Alloreactive CD4 T lymphocytes responsible for acute and chronic graft-versus-host disease are contained within the CD45RChigh but not the CD45RClow subset. Eur J Immunol 2004; 34: 408.
    • (2004) Eur J Immunol , vol.34 , pp. 408
    • Xystrakis, E.1    Bernard, I.2    Dejean, A.S.3
  • 22
    • 0014024473 scopus 로고
    • Chemotherapy in the treatment of leukemia and Wilms' tumor
    • Farber S. Chemotherapy in the treatment of leukemia and Wilms' tumor. JAMA 1966; 198: 826.
    • (1966) JAMA , vol.198 , pp. 826
    • Farber, S.1
  • 23
    • 0031954699 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of aminopterin in patients with refractory malignancies
    • Ratliff AF, Wilson J, Hum M, et al. Phase I and pharmacokinetic trial of aminopterin in patients with refractory malignancies. J Clin Oncol 1998; 16: 1458.
    • (1998) J Clin Oncol , vol.16 , pp. 1458
    • Ratliff, A.F.1    Wilson, J.2    Hum, M.3
  • 24
    • 1642468890 scopus 로고    scopus 로고
    • Aminopterin-human serum albumin conjugate (AP-HSA): Uptake and cytotoxic effects in tumor cell lines
    • Eschen N, Bauder-Wust U, Frei E, et al. Aminopterin-human serum albumin conjugate (AP-HSA): uptake and cytotoxic effects in tumor cell lines. Int J Clin Pharmacol Ther 2002; 40: 564.
    • (2002) Int J Clin Pharmacol Ther , vol.40 , pp. 564
    • Eschen, N.1    Bauder-Wust, U.2    Frei, E.3
  • 25
    • 0036021021 scopus 로고    scopus 로고
    • Efficacy and tolerability of an aminopterin-albumin conjugate in tumor- Bearing rats
    • Kremer P, Hartung G, Bauder-Wust U, et al. Efficacy and tolerability of an aminopterin-albumin conjugate in tumor- bearing rats. Anticancer Drugs 2002; 13: 615.
    • (2002) Anticancer Drugs , vol.13 , pp. 615
    • Kremer, P.1    Hartung, G.2    Bauder-Wust, U.3
  • 26
    • 0005042903 scopus 로고    scopus 로고
    • Albumin-based drug carriers: Comparison between serum albumins of different species on pharmacokinetics and tumor uptake of the conjugate
    • Stehle G, Wunder A, Schrenk HH, et al. Albumin-based drug carriers: comparison between serum albumins of different species on pharmacokinetics and tumor uptake of the conjugate. Anticancer Drugs 1999; 10: 785.
    • (1999) Anticancer Drugs , vol.10 , pp. 785
    • Stehle, G.1    Wunder, A.2    Schrenk, H.H.3
  • 27
    • 0033136513 scopus 로고    scopus 로고
    • Detection of residual aneuploid leukemic cells by "continuous gating."
    • Kleine HD, Zech I, Nowak R, et al. Detection of residual aneuploid leukemic cells by "continuous gating." Cytometry 1999; 36: 71.
    • (1999) Cytometry , vol.36 , pp. 71
    • Kleine, H.D.1    Zech, I.2    Nowak, R.3
  • 28
    • 0033868623 scopus 로고    scopus 로고
    • Laser-induced fluorescence detection of malignant gliomas using fluorescein-labeled serum albumin: Experimental and preliminary clinical results
    • Kremer P, Wunder A, Sinn H, et al. Laser-induced fluorescence detection of malignant gliomas using fluorescein-labeled serum albumin: experimental and preliminary clinical results. Neurol Res 2000; 22: 481.
    • (2000) Neurol Res , vol.22 , pp. 481
    • Kremer, P.1    Wunder, A.2    Sinn, H.3
  • 29
    • 0033729734 scopus 로고    scopus 로고
    • Antiproliferative and antiinflammatory effects of methotrexate on cultured differentiating myeloid monocytic cells (THP-1) but not on synovial macrophages from patients with rheumatoid arthritis
    • Cutolo M, Bisso A, Sulli A, et al. Antiproliferative and antiinflammatory effects of methotrexate on cultured differentiating myeloid monocytic cells (THP-1) but not on synovial macrophages from patients with rheumatoid arthritis. J Rheumatol 2000; 27: 2551.
    • (2000) J Rheumatol , vol.27 , pp. 2551
    • Cutolo, M.1    Bisso, A.2    Sulli, A.3
  • 30
    • 0032440537 scopus 로고    scopus 로고
    • Methotrexate inhibits LPS-induced tumor necrosis factor production in vivo
    • Durez P, Appelboom T, Vray B, et al. Methotrexate inhibits LPS-induced tumor necrosis factor production in vivo. Eur Cytokine Netw 1998; 9: 669.
    • (1998) Eur Cytokine Netw , vol.9 , pp. 669
    • Durez, P.1    Appelboom, T.2    Vray, B.3
  • 31
    • 20044386782 scopus 로고    scopus 로고
    • Cyclosporine A and mycophenolate mofetil vs cyclosporine A and methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings
    • Neumann F, Graef T, Tapprich C, et al. Cyclosporine A and mycophenolate mofetil vs cyclosporine A and methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings. Bone Marrow Transplant 2005; 35: 1089.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 1089
    • Neumann, F.1    Graef, T.2    Tapprich, C.3
  • 32
    • 2642688922 scopus 로고    scopus 로고
    • Antitumor activity of MTX-HSA conjugates in rats
    • Wunder A, Stehle G, Sinn H et al. Antitumor activity of MTX-HSA conjugates in rats. Eur J Cancer 1997; 33: 178.
    • (1997) Eur J Cancer , vol.33 , pp. 178
    • Wunder, A.1    Stehle, G.2    Sinn, H.3


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