Effect of age on progesterone receptor expression, and osteoprogenitor proliferation and differentiation in female rat vertebral cell populations

Journal of Endocrinology

Volumn 190, Issue 2, 2006, Pages 261-270

  Pei, Weidong ^a   Bellows, Carlton G ^a   Jia, Yongheng ^a   Heersche, Johan N M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ESTROGEN; PROGESTERONE; PROGESTERONE RECEPTOR A; PROGESTERONE RECEPTOR B;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE CELL; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION FUNCTION; ESTROGEN BLOOD LEVEL; FEMALE; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; UPREGULATION; VERTEBRA;

AGING; ANIMALS; BONE AND BONES; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DEXAMETHASONE; ESTROGENS; FEMALE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; PROGESTERONE; RATS; RATS, WISTAR; RECEPTORS, PROGESTERONE; SPINE; STEM CELLS;

EID: 33747887090     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06803     Document Type: Article

References (40)

1. Aronica SM & Katzenellenbogen BS 1991 Progesterone receptor regulation in uterine cells: stimulation by estrogen, cyclic adenosine 3′,5′-monophosphate, and insulin-like growth factor I and suppression by antiestrogens and protein kinase inhibitors. Endocrinology 128 2045-2052.
2. Bellows CG & Aubin JE 1989 Determination of numbers of osteoprogenitors present in isolated fetal rat calvaria cells in vitro. Developmental Biology 133 8-13.
3. Bellows CG, Pei W, Jia Y & Heersche JNM 2003 Proliferation, differentiation and self-renewal of osteoprogenitors in vertebral cell populations from aged and young female rats. Mechanism of Ageing and Development 124 747-757.
4. Chakraborty TR & Gore AC 2004 Aging-related changes in ovarian hormones, their receptors, and neuroendocrine function. Experimental Biology and Medicine 229 977-987.
5. Cui L, Ma YF, Yao W, Zhou H, Setterberg RB, Liang TC & Jee WS 2001 Cancellous bone of aged rats maintains its capacity to respond vigorously to the anabolic effects of prostaglandin E2 by modeling-dependent bone gain. Journal of Bone and Mineral Metabolism 19 29-37.
6. Funabashi T, Kleopoulos SP, Brooks PJ, Kimura F, Pfaff DW, Shinohara K & Mobbs CV 2000 Changes in estrogenic regulation of estrogen receptor alpha mRNA and progesterone receptor mRNA in the female rat hypothalamus during aging: an in situ hybridization study. Neuroscience Research 38 85-92.
7. Giangrande PH & McDonnell DP 1999 The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene. Recent Progress of Hormone Research 54 291-313.
8. Graham JD & Clarke CL 1997 Physiological action of progesterone in target tissues. Endocrine Review 18 502-519.
9. Graham JD & Clarke CL 2002 Expression and transcriptional activity of progesterone receptor A and progesterone receptor B in mammalian cells. Breast Cancer Research 4 187-190.
10. Greene GL, Harris K, Bova R, Kinders R, Moore B & Nolan C 1988 Purification of T47D human progesterone receptor and immumochemical characterization with monoclonal antibodies. Molecular Endocrinology 2 714-726.
11. Harris SA, Tau KR, Enger RJ, Toft DO, Riggs BL & Spelsberg TC 1995 Estrogen response in the hFOB 1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene. Journal of Cellular Biochemistry 59 193-201.
12. Haywood SA, Simonian SX, van der Beek EM, Bicknell RJ & Herbison AE 1999 Fluctuating estrogen and progesterone receptor expression in brainstem norepinephrine neurons through the rat estrous cycle. Endocrinology 140 3255-3263.
13. Hilborn S & Krahn J 1987 Effect of time of exposure of serum to gel-barrier tubes on results for progesterone and some other endocrine tests. Clinical Chemistry 33 203-204.
14. Hovland AR, Powell RL, Takimoto GS, Tung L & Horwitz KB 1998 An N-terminal inhibitory function, IF, suppresses transcription by the A-isoform but not the B-isoform of human progesterone receptors. Journal of Biological Chemistry 273 5455-5460.
15. Huang HH & Meites J 1975 Reproductive capacity of aging female rats. Neuroendocrinology 17 289-295.
16. Ishida Y & Heersche JN 1997 Progesterone stimulates proliferation and differentiation of osteoprogenitor cells in bone cell populations derived from adult female but not from adult male rats. Bone 20 17-25.
17. Ishida Y & Heersche JNM 1999 Progesterone- and dexamethasone-dependent osteoprogenitors in bone cell populations derived from rat vertebrae are different and distinct. Endocrinology 140 3210-3218.
18. Johnson MR, Carter G, Grint C & Lightman SL 1993 Relationship between ovarian steroids, gonadotrophins and relaxin during the menstrual cycle. Acta Endocrinologica 129 121-125.
19. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
20. LeFevre J & McClintock MK 1988 Reproductive senescence in female rats: a longitudinal study of individual differences in estrous cycles and behavior. Biological Reproduction 38 780-789.
21. Lessey BA, Killam AP, Metzger DA, Haney AF, Greene GL & McCarty KS, Jr. 1991 Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. Journal of Clinical Endocrinology and Metabolism 67 334-440.
22. Liang M, Liao EY, Xu X, Luo XH & Xiao XH 2003 Effects of progesterone and 18-methyl levonorgestrel on osteoblastic cells. Endocrine Research 29 483-501.
23. Lu KH, Hopper BR, Vargo TM & Yen SS 1979 Chronological changes in sex steroid, gonadotropin and prolactin secretions in aging female rats displaying different reproductive states. Biological Reproduction 21 193-203.
24. Meyer ME, Quirin-Stricker C, Lerouge T, Bocquel MT & Gronemeyer H 1992 A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms. Journal of Biological Chemistry 267 10882-10887.
25. Mulac-Jericevic B & Conneely OM 2004 Reproductive tissue selective actions of progesterone receptors. Reproductive tissue selective actions of progesterone receptors. Reproduction 128 139-146.
26. Mulac-Jericevic B, Mullinax RA, DeMayo FJ, Lydon JP & Conneely OM 2000 Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science 289 1751-1754.
27. Pei W, Bellows CG, Elsubeihi ES & Heersche JN 2003 Effect of ovariectomy on dexamethasone- and progesterone-dependent osteoprogenitors in vertebral and femoral rat bone cell populations. Bone 33 822-830.
28. Pieber D, Allport VC & Bennett PR 2001 Progesterone receptor isoform A inhibits isoform B-mediated transactivation in human amnion. European Journal of Pharmacology 427 7-11.
29. Read LD, Snider CE, Miller JS, Greene GL & Katzenellenbogen BS 1988 Ligand-modulated regulation of progesterone receptor messenger ribonucleic acid and protein in human breast cancer cell lines. Molecular Endocrinology 2 263-271.
30. Rickard DJ, Waters KM, Ruesink TJ, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Riggs BL & Spelsberg TC 2002 Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts. Journal of Bone Mineral Research 17 580-592.
31. Scheven BA, Damen CA, Hamilton NJ, Verhaar HJ & Duursma SA 1992 Stimulatory effects of estrogen and progesterone on proliferation and differentiation of normal human osteoblast-like cells in vitro. Biochemical and Biophysical Research Communications 186 54-60.
32. Schneider W, Ramachandran C, Satyaswaroop PG & Shyamala G 1991 Murine progesterone receptor exists predominantly as the 83-kilodalton 'A' form. Journal of Steroid Biochemistry and Molecular Biology 38 285-291.
33. Sibonga JD, Zhang M, Ritman EL & Turner RT 2000 Restoration of bone mass in the severely osteopenic senescent rat. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 55 B71-B84.
34. Slootweg MC, Ederveen AG, Schot LP, Schoonen WG & Kloosterboer HJ 1992 Oestrogen and progesterone synergistically stimulate human and rat osteoblast proliferation. Journal of Endocrinology 133 R5-R8.
35. Sternberger LA 1979 Immunocytochemistry. In Immunocytochemistry, 2nd edn, p 104. Wiley, New York, NY, USA.
36. Tora L, Gronemeyer H, Turcotte B, Gaub MP & Chambon P 1988 The N-terminal region of the chicken progesterone receptor specifies target gene activation. Nature 333 185-188.
37. Towbin H, Staehelin T & Gordon J 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Biotechnology 24 145-149.
38. Vegeto E, Shahbaz MM, Wen DX, Goldman ME, O'Malley BW & McDonnell DP 1993 Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Molecular Endocrinology 7 1244-1255.
39. Verhaar HJ, Damen CA, Dunrsma SA & Scheven BA 1994 A comparison of the action of progestins and estrogen on the growth and differentiation of normal adult human osteoblast-like cells in vitro. Bone 15 307-311.
40. Zhou S, Zilberman Y, Wassermann K, Bain SD, Sadovsky Y & Gazit D 2001 Estrogen modulates estrogen receptor alpha and beta expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice. Journal of Cellular Biochemistry (Suppl 36) 144-155.