Protection of the peptide glutathione by complex formation with α-cyclodextrin: NMR spectroscopic analysis and stability study

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 64, Issue 2, 2006, Pages 146-153

  Garcia Fuentes, M ^a   Trapani, A ^a   Alonso, M J ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cyclodextrins; Glutathione; Inclusion complex; Nuclear magnetic resonance; Peptide stability

Indexed keywords

EXOPEPTIDASE; GAMMA GLUTAMYLCYSTEINYLGLYCINE ALPHA CYCLODEXTRIN COMPLEX; GAMMA GLUTAMYLTRANSFERASE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; TITRIMETRY;

ALPHA-CYCLODEXTRINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EXOPEPTIDASES; GAMMA-GLUTAMYLTRANSFERASE; GLUTAMIC ACID; GLUTATHIONE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; PROTEIN BINDING; TECHNOLOGY, PHARMACEUTICAL;

EID: 33747885185     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.05.010     Document Type: Article

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