메뉴 건너뛰기




Volumn 12, Issue 5, 2006, Pages 513-518

An update on antenatal screening for Down's syndrome and specific implications for assisted reproduction pregnancies

Author keywords

Down's syndrome; Integrated screening; Nuchal translucency; Screening

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN; INHIBIN A;

EID: 33747883920     PISSN: 13554786     EISSN: 14602369     Source Type: Journal    
DOI: 10.1093/humupd/dml021     Document Type: Review
Times cited : (28)

References (69)
  • 1
    • 16244402632 scopus 로고    scopus 로고
    • First-trimester screening for fetal aneuploidy
    • ACOG Committee Opinion #296
    • ACOG Committee Opinion #296 (2004) First-trimester screening for fetal aneuploidy. Obstet Gynecol 104,215-217.
    • (2004) Obstet Gynecol , vol.104 , pp. 215-217
  • 3
    • 12644295986 scopus 로고    scopus 로고
    • Down's syndrome screening marker levels following assisted reproduction
    • Barkai G, Goldman B, Ries L, Chaki R, Dor J and Cuckle H (1996) Down's syndrome screening marker levels following assisted reproduction. Prenat Diagn 16,1111-1114.
    • (1996) Prenat Diagn , vol.16 , pp. 1111-1114
    • Barkai, G.1    Goldman, B.2    Ries, L.3    Chaki, R.4    Dor, J.5    Cuckle, H.6
  • 4
    • 0036378243 scopus 로고    scopus 로고
    • One-stop clinic for assessment of risk for trisomy 21 at 11-14 weeks: A prospective study of 15 030 pregnancies
    • Bindra R, Heath V, Liao A, Spencer K and Nicolaides KH (2002) One-stop clinic for assessment of risk for trisomy 21 at 11-14 weeks: A prospective study of 15 030 pregnancies. Ultrasound Obstet Gynecol 20,219-225.
    • (2002) Ultrasound Obstet Gynecol , vol.20 , pp. 219-225
    • Bindra, R.1    Heath, V.2    Liao, A.3    Spencer, K.4    Nicolaides, K.H.5
  • 5
    • 4043102494 scopus 로고    scopus 로고
    • Women and health care professionals' preferences for Down's Syndrome screening tests: A conjoint analysis study
    • Bishop AJ, Marteau TM, Armstrong D, Chitty LS, Longworth L, Buxton MH and Berlin C (2004) Women and health care professionals' preferences for Down's Syndrome screening tests: A conjoint analysis study. BJOG 111,775-779.
    • (2004) BJOG , vol.111 , pp. 775-779
    • Bishop, A.J.1    Marteau, T.M.2    Armstrong, D.3    Chitty, L.S.4    Longworth, L.5    Buxton, M.H.6    Berlin, C.7
  • 6
    • 27144504477 scopus 로고    scopus 로고
    • First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers
    • Borrell A, Gonce A, Martinez JM, Borobio V, Fortuny A, Coll O and Cuckle H (2005) First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers. Prenat Diagn 25,901-905.
    • (2005) Prenat Diagn , vol.25 , pp. 901-905
    • Borrell, A.1    Gonce, A.2    Martinez, J.M.3    Borobio, V.4    Fortuny, A.5    Coll, O.6    Cuckle, H.7
  • 8
    • 0036336724 scopus 로고    scopus 로고
    • Comparison of first trimester, second trimester and integrated Down's syndrome screening results in unaffected pregnancies
    • Canini S, Prefumo F, Famularo L, Venturini PL, Palazzeso V and De Biasio P (2002) Comparison of first trimester, second trimester and integrated Down's syndrome screening results in unaffected pregnancies. Clin Chem Lab Med 40,600-603.
    • (2002) Clin Chem Lab Med , vol.40 , pp. 600-603
    • Canini, S.1    Prefumo, F.2    Famularo, L.3    Venturini, P.L.4    Palazzeso, V.5    De Biasio, P.6
  • 9
    • 0035904786 scopus 로고    scopus 로고
    • Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: An observational study
    • Cicero S, Curcio P, Papageorghiou A, Sonek J and Nicolaides K (2001) Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: An observational study. Lancet 358,1665-1667.
    • (2001) Lancet , vol.358 , pp. 1665-1667
    • Cicero, S.1    Curcio, P.2    Papageorghiou, A.3    Sonek, J.4    Nicolaides, K.5
  • 10
    • 0037393802 scopus 로고    scopus 로고
    • Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks
    • Cicero S, Bindra R, Rembouskos G, Spencer K and Nicolaides KH (2003) Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks. Prenat Diagn 23,306-310.
    • (2003) Prenat Diagn , vol.23 , pp. 306-310
    • Cicero, S.1    Bindra, R.2    Rembouskos, G.3    Spencer, K.4    Nicolaides, K.H.5
  • 11
    • 0021248894 scopus 로고
    • Maternal serum alpha-fetoprotein measurement: A screening test for Down syndrome
    • Cuckle HS, Wald NJ and Lindenbaum RH (1984) Maternal serum alpha-fetoprotein measurement: A screening test for Down syndrome. Lancet 1,926-929.
    • (1984) Lancet , vol.1 , pp. 926-929
    • Cuckle, H.S.1    Wald, N.J.2    Lindenbaum, R.H.3
  • 12
    • 0023197081 scopus 로고
    • Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level
    • Cuckle HS, Wald NJ and Thompson SG (1987) Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol 94,387-402.
    • (1987) Br J Obstet Gynaecol , vol.94 , pp. 387-402
    • Cuckle, H.S.1    Wald, N.J.2    Thompson, S.G.3
  • 13
    • 23644431888 scopus 로고    scopus 로고
    • First and second trimester evaluation of risk for fetal aneuploidy: The secondary outcomes of the FASTER Trial
    • D'Alton M and Cleary-Goldman J (2005) First and second trimester evaluation of risk for fetal aneuploidy: The secondary outcomes of the FASTER Trial. Semin Perinatol 29,240-246.
    • (2005) Semin Perinatol , vol.29 , pp. 240-246
    • D'Alton, M.1    Cleary-Goldman, J.2
  • 14
    • 0036854161 scopus 로고    scopus 로고
    • Antenatal Down syndrome screening in the United States in 2001: A survey of maternal-fetal medicine specialists
    • Egan JF, Kaminsky LM, DeRoche ME, Barsoom MJ, Borgida AF and Benn PA (2002) Antenatal Down syndrome screening in the United States in 2001: A survey of maternal-fetal medicine specialists. Am J Obstet Gynecol 187,1230-1234.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 1230-1234
    • Egan, J.F.1    Kaminsky, L.M.2    DeRoche, M.E.3    Barsoom, M.J.4    Borgida, A.F.5    Benn, P.A.6
  • 15
    • 0030985191 scopus 로고    scopus 로고
    • Screening for Down syndrome during first trimester: A prospective study using free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A
    • Forest JC, Masse J and Moutquin JM (1997) Screening for Down syndrome during first trimester: A prospective study using free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A. Clin Biochem 30,333-338.
    • (1997) Clin Biochem , vol.30 , pp. 333-338
    • Forest, J.C.1    Masse, J.2    Moutquin, J.M.3
  • 17
    • 0345874801 scopus 로고    scopus 로고
    • Different preferences for prenatal diagnosis in pregnancies following assisted reproduction versus spontaneous conception
    • Geipel A, Berg C, Katalinic A, Ludwig M, Germer U, Diedrich K and Gembruch U (2004) Different preferences for prenatal diagnosis in pregnancies following assisted reproduction versus spontaneous conception. Reprod Biomed Online 8,119-124.
    • (2004) Reprod Biomed Online , vol.8 , pp. 119-124
    • Geipel, A.1    Berg, C.2    Katalinic, A.3    Ludwig, M.4    Germer, U.5    Diedrich, K.6    Gembruch, U.7
  • 22
    • 0034931795 scopus 로고    scopus 로고
    • First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction
    • Liao AW, Heath V, Kametas N, Spencer K and Nicolaides KH (2001) First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction. Hum Reprod 16,1501-1504.
    • (2001) Hum Reprod , vol.16 , pp. 1501-1504
    • Liao, A.W.1    Heath, V.2    Kametas, N.3    Spencer, K.4    Nicolaides, K.H.5
  • 23
    • 0026761364 scopus 로고
    • Second-trimester maternal serum immunoreactive inhibin as a marker for fetal Down's syndrome
    • van Lith JM, Pratt JJ, Beekhuis JR and Mantingh A (1992) Second-trimester maternal serum immunoreactive inhibin as a marker for fetal Down's syndrome. Prenat Diagn 12,801-806.
    • (1992) Prenat Diagn , vol.12 , pp. 801-806
    • van Lith, J.M.1    Pratt, J.J.2    Beekhuis, J.R.3    Mantingh, A.4
  • 27
    • 0027508567 scopus 로고
    • Anxiety, knowledge and satisfaction in women receiving false positive results on routine prenatal screening: A randomized controlled trial
    • Marteau TM, Kidd J, Michie S, Cook R, Johnston M and Shaw RW (1993) Anxiety, knowledge and satisfaction in women receiving false positive results on routine prenatal screening: A randomized controlled trial. J Psychosom Obstet Gynaecol 14,185-196.
    • (1993) J Psychosom Obstet Gynaecol , vol.14 , pp. 185-196
    • Marteau, T.M.1    Kidd, J.2    Michie, S.3    Cook, R.4    Johnston, M.5    Shaw, R.W.6
  • 28
    • 1542351161 scopus 로고    scopus 로고
    • Integrated first- and second-trimester Down syndrome screening test among unaffected IVF pregnancies
    • Maymon R and Shulman A (2004) Integrated first- and second-trimester Down syndrome screening test among unaffected IVF pregnancies. Prenat Diagn 24,125-129.
    • (2004) Prenat Diagn , vol.24 , pp. 125-129
    • Maymon, R.1    Shulman, A.2
  • 29
    • 0034814231 scopus 로고    scopus 로고
    • Nuchal translucency measurement and pregnancy outcome after assisted conception versus spontaneously conceived twins
    • Maymon R, Jauniaux E, Holmes A, Wiener YM, Dreazen E and Herman A (2001) Nuchal translucency measurement and pregnancy outcome after assisted conception versus spontaneously conceived twins. Hum Reprod 16,1999-2004.
    • (2001) Hum Reprod , vol.16 , pp. 1999-2004
    • Maymon, R.1    Jauniaux, E.2    Holmes, A.3    Wiener, Y.M.4    Dreazen, E.5    Herman, A.6
  • 30
    • 26044449605 scopus 로고    scopus 로고
    • Current concepts of Down syndrome screening tests in assisted reproduction twin pregnancies: Another double trouble
    • Maymon R, Neeman O, Shulman A, Rosen H and Herman A (2005) Current concepts of Down syndrome screening tests in assisted reproduction twin pregnancies: Another double trouble. Prenat Diagn 25,746-750.
    • (2005) Prenat Diagn , vol.25 , pp. 746-750
    • Maymon, R.1    Neeman, O.2    Shulman, A.3    Rosen, H.4    Herman, A.5
  • 31
    • 0021247504 scopus 로고
    • An association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities
    • Merkatz IR, Nitowsky HM, Macri JN and Johnson WE (1984) An association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities. Am J Obstet Gynecol 148,886-894.
    • (1984) Am J Obstet Gynecol , vol.148 , pp. 886-894
    • Merkatz, I.R.1    Nitowsky, H.M.2    Macri, J.N.3    Johnson, W.E.4
  • 32
    • 0031081155 scopus 로고    scopus 로고
    • Aneuploidy in twin gestations: When is maternal age advanced?
    • Meyers C, Adam R, Dungan J and Prenger V (1997) Aneuploidy in twin gestations: When is maternal age advanced? Obstet Gynecol 89,248-251.
    • (1997) Obstet Gynecol , vol.89 , pp. 248-251
    • Meyers, C.1    Adam, R.2    Dungan, J.3    Prenger, V.4
  • 35
    • 13444272238 scopus 로고    scopus 로고
    • Antenatal screening - Working standards
    • National Down's Syndrome Screening Programme for England. NHS
    • National Down's Syndrome Screening Programme for England (2004) Antenatal screening - working standards. NHS.
    • (2004)
  • 36
    • 11844287911 scopus 로고    scopus 로고
    • Antenatal care: Routine care for the healthy pregnant woman
    • NICE National Collaborating Centre for Women's and Children's Health. Commissioned by the National Institute for Clinical Excellence (NICE). RCOG Press, London
    • NICE (2005) National Collaborating Centre for Women's and Children's Health. Commissioned by the National Institute for Clinical Excellence (NICE). Antenatal care: Routine care for the healthy pregnant woman. RCOG Press, London.
    • (2005)
  • 37
    • 4043063702 scopus 로고    scopus 로고
    • Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities
    • Nicolaides KH (2004) Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities. Am J Obstet Gynecol 191,45-67.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 45-67
    • Nicolaides, K.H.1
  • 38
    • 0026562612 scopus 로고
    • Fetal nuchal translucency: Ultrasound screening for chromosomal defects in first trimester of pregnancy
    • Nicolaides KH, Azar G, Byrne D, Mansur C and Marks K (1992) Fetal nuchal translucency: Ultrasound screening for chromosomal defects in first trimester of pregnancy. BMJ 304,867-869.
    • (1992) BMJ , vol.304 , pp. 867-869
    • Nicolaides, K.H.1    Azar, G.2    Byrne, D.3    Mansur, C.4    Marks, K.5
  • 39
    • 15944409220 scopus 로고    scopus 로고
    • Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: Results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening
    • Nicolaides KH, Spencer K, Avgidou K, Faiola S and Falcon O (2005) Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: Results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 25,221-226.
    • (2005) Ultrasound Obstet Gynecol , vol.25 , pp. 221-226
    • Nicolaides, K.H.1    Spencer, K.2    Avgidou, K.3    Faiola, S.4    Falcon, O.5
  • 41
    • 0032959421 scopus 로고    scopus 로고
    • Psychosocial experiences in women facing fertility problems - A comparative survey
    • Oddens BJ, den Tonkelaar I and Nieuwenhuyse H (1999) Psychosocial experiences in women facing fertility problems - a comparative survey. Hum Reprod 14,255-261.
    • (1999) Hum Reprod , vol.14 , pp. 255-261
    • Oddens, B.J.1    den Tonkelaar, I.2    Nieuwenhuyse, H.3
  • 42
    • 23644459852 scopus 로고    scopus 로고
    • Patient and health professional acceptance of integrated serum screening for Down syndrome
    • Palomaki GE, Kloza EM, Haddow JE, Williams J and Knight GJ (2005) Patient and health professional acceptance of integrated serum screening for Down syndrome. Semin Perinatol 29,247-251.
    • (2005) Semin Perinatol , vol.29 , pp. 247-251
    • Palomaki, G.E.1    Kloza, E.M.2    Haddow, J.E.3    Williams, J.4    Knight, G.J.5
  • 43
    • 0029181608 scopus 로고
    • The implementation of first-trimester scanning at 10-13 weeks' gestation and the measurement of fetal nuchal translucency thickness in two maternity units
    • Pandya PP, Goldberg H, Walton B, Riddle A, Shelley S, Snijders RJ and Nicolaides KH (1995) The implementation of first-trimester scanning at 10-13 weeks' gestation and the measurement of fetal nuchal translucency thickness in two maternity units. Ultrasound Obstet Gynecol 5,20-25.
    • (1995) Ultrasound Obstet Gynecol , vol.5 , pp. 20-25
    • Pandya, P.P.1    Goldberg, H.2    Walton, B.3    Riddle, A.4    Shelley, S.5    Snijders, R.J.6    Nicolaides, K.H.7
  • 44
    • 0346458746 scopus 로고    scopus 로고
    • Maternal midtrimester free beta-HCG and AFP serum levels in spontaneous singleton pregnancies complicated by gestational diabetes mellitus, pregnancy-induced hypertension or obstetric cholestasis
    • Raty R, Anttila L, Virtanen A, Koskinen P, Laitinen P, Morsky P, Tiitinen A, Martikainen H and Ekblad U (2003) Maternal midtrimester free beta-HCG and AFP serum levels in spontaneous singleton pregnancies complicated by gestational diabetes mellitus, pregnancy-induced hypertension or obstetric cholestasis. Prenat Diagn 23,1045-1048.
    • (2003) Prenat Diagn , vol.23 , pp. 1045-1048
    • Raty, R.1    Anttila, L.2    Virtanen, A.3    Koskinen, P.4    Laitinen, P.5    Morsky, P.6    Tiitinen, A.7    Martikainen, H.8    Ekblad, U.9
  • 45
    • 16444367571 scopus 로고    scopus 로고
    • Second-trimester maternal serum screening for Down syndrome in in vitro fertilization pregnancies
    • Rice JD, McIntosh SF and Halstead AC (2005) Second-trimester maternal serum screening for Down syndrome in in vitro fertilization pregnancies. Prenat Diagn 25,234-238.
    • (2005) Prenat Diagn , vol.25 , pp. 234-238
    • Rice, J.D.1    McIntosh, S.F.2    Halstead, A.C.3
  • 46
    • 0036126080 scopus 로고    scopus 로고
    • The first trimester 'combined test' for the detection of Down syndrome pregnancies in 4939 unselected pregnancies
    • Schuchter K, Hafner E, Stangl G, Metzenbauer M, Hofinger D and Philipp K (2002) The first trimester 'combined test' for the detection of Down syndrome pregnancies in 4939 unselected pregnancies. Prenat Diagn 22,211-215.
    • (2002) Prenat Diagn , vol.22 , pp. 211-215
    • Schuchter, K.1    Hafner, E.2    Stangl, G.3    Metzenbauer, M.4    Hofinger, D.5    Philipp, K.6
  • 47
    • 0029847927 scopus 로고    scopus 로고
    • Screening for trisomy 21 in twin pregnancies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation
    • Sebire NJ, Snijders RJ, Hughes K, Sepulveda W and Nicolaides KH (1996) Screening for trisomy 21 in twin pregnancies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation. Br J Obstet Gynaecol 103,999-1003.
    • (1996) Br J Obstet Gynaecol , vol.103 , pp. 999-1003
    • Sebire, N.J.1    Snijders, R.J.2    Hughes, K.3    Sepulveda, W.4    Nicolaides, K.H.5
  • 48
    • 4444300609 scopus 로고    scopus 로고
    • Diagnostic mid trimester amniocentesis: How safe?
    • Seeds JW (2004) Diagnostic mid trimester amniocentesis: How safe? Am J Obstet Gynecol 191,607-615.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 607-615
    • Seeds, J.W.1
  • 49
    • 0042090395 scopus 로고    scopus 로고
    • Intra- and interoperator variability in fetal nasal bone assessment at 11-14 weeks of gestation
    • Senat MV, Bernard JP, Boulvain M and Ville Y (2003) Intra- and interoperator variability in fetal nasal bone assessment at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 22,138-141.
    • (2003) Ultrasound Obstet Gynecol , vol.22 , pp. 138-141
    • Senat, M.V.1    Bernard, J.P.2    Boulvain, M.3    Ville, Y.4
  • 50
    • 27744594798 scopus 로고    scopus 로고
    • Choosing the best prenatal screening protocol
    • Simpson JL (2005) Choosing the best prenatal screening protocol. N Engl J Med 353,2068-2070.
    • (2005) N Engl J Med , vol.353 , pp. 2068-2070
    • Simpson, J.L.1
  • 51
    • 0037333795 scopus 로고    scopus 로고
    • Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: A review of three years experience
    • Spencer K and Nicolaides KH (2003) Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: A review of three years experience. BJOG 110,276-280.
    • (2003) BJOG , vol.110 , pp. 276-280
    • Spencer, K.1    Nicolaides, K.H.2
  • 52
    • 0026748639 scopus 로고
    • Free beta-hCG as first-trimester marker for fetal trisomy
    • Spencer K, Macri JN, Aitken DA and Connor JM (1992) Free beta-hCG as first-trimester marker for fetal trisomy. Lancet 339,1480.
    • (1992) Lancet , vol.339 , pp. 1480
    • Spencer, K.1    Macri, J.N.2    Aitken, D.A.3    Connor, J.M.4
  • 53
    • 0033795008 scopus 로고    scopus 로고
    • One stop clinic for assessment of risk for fetal anomalies: A report of the first year of prospective screening for chromosomal anomalies in the first trimester
    • Spencer K, Spencer CE, Power M, Moakes A and Nicolaides KH (2000) One stop clinic for assessment of risk for fetal anomalies: A report of the first year of prospective screening for chromosomal anomalies in the first trimester. BJOG 107,1271-1275.
    • (2000) BJOG , vol.107 , pp. 1271-1275
    • Spencer, K.1    Spencer, C.E.2    Power, M.3    Moakes, A.4    Nicolaides, K.H.5
  • 54
    • 0037333249 scopus 로고    scopus 로고
    • Screening for chromosomal abnormalities in the first trimester using ultrasound and maternal serum biochemistry in a one-stop clinic: A review of three years prospective experience
    • Spencer K, Spencer CE, Power M, Dawson C and Nicolaides KH (2003) Screening for chromosomal abnormalities in the first trimester using ultrasound and maternal serum biochemistry in a one-stop clinic: A review of three years prospective experience. BJOG 110,281-286.
    • (2003) BJOG , vol.110 , pp. 281-286
    • Spencer, K.1    Spencer, C.E.2    Power, M.3    Dawson, C.4    Nicolaides, K.H.5
  • 55
    • 0025165471 scopus 로고
    • Nuchal fluid accumulation in trisomy-21 detected by vaginosonography in first trimester
    • Szabo J and Gellen J (1990) Nuchal fluid accumulation in trisomy-21 detected by vaginosonography in first trimester. Lancet 336,1133.
    • (1990) Lancet , vol.336 , pp. 1133
    • Szabo, J.1    Gellen, J.2
  • 56
  • 57
    • 0028521549 scopus 로고
    • What are we screening for?
    • Wald NJ (1994) What are we screening for? J Med Screen 1,205.
    • (1994) J Med Screen , vol.1 , pp. 205
    • Wald, N.J.1
  • 58
    • 0030883821 scopus 로고    scopus 로고
    • Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome
    • Wald NJ and Hackshaw AK (1997) Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome. Prenat Diagn 17,821-829.
    • (1997) Prenat Diagn , vol.17 , pp. 821-829
    • Wald, N.J.1    Hackshaw, A.K.2
  • 60
    • 0017685970 scopus 로고
    • Maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. Report of U.K. collaborative study on alpha-fetoprotein in relation to neural-tube defects
    • Wald NJ, Cuckle H, Brock JH, Peto R, Polani PE and Woodford FP (1977) Maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. Report of U.K. collaborative study on alpha-fetoprotein in relation to neural-tube defects. Lancet 1,1323-1332.
    • (1977) Lancet , vol.1 , pp. 1323-1332
    • Wald, N.J.1    Cuckle, H.2    Brock, J.H.3    Peto, R.4    Polani, P.E.5    Woodford, F.P.6
  • 62
    • 0026652005 scopus 로고
    • First trimester concentrations of pregnancy associated plasma protein A and placental protein 14 in Down's syndrome
    • Wald N, Stone R, Cuckle HS, Grudzinskas JG, Barkai G, Brambati B, Teisner B and Fuhrmann W (1992) First trimester concentrations of pregnancy associated plasma protein A and placental protein 14 in Down's syndrome. BMJ 305,28.
    • (1992) BMJ , vol.305 , pp. 28
    • Wald, N.1    Stone, R.2    Cuckle, H.S.3    Grudzinskas, J.G.4    Barkai, G.5    Brambati, B.6    Teisner, B.7    Fuhrmann, W.8
  • 63
    • 0033549839 scopus 로고    scopus 로고
    • Integrated screening for Down's syndrome on the basis of tests performed during the first and second trimesters
    • Wald NJ, Watt HC and Hackshaw AK (1999a) Integrated screening for Down's syndrome on the basis of tests performed during the first and second trimesters. N Engl J Med 341,461-467.
    • (1999) N Engl J Med , vol.341 , pp. 461-467
    • Wald, N.J.1    Watt, H.C.2    Hackshaw, A.K.3
  • 64
    • 0032762014 scopus 로고    scopus 로고
    • Serum markers for Down's syndrome in women who have had in vitro fertilisation: Implications for antenatal screening
    • Wald NJ, White N, Morris JK, Huttly WJ and Canick JE (1999b) Serum markers for Down's syndrome in women who have had in vitro fertilisation: Implications for antenatal screening. Br J Obstet Gynaecol 106,1304-1306.
    • (1999) Br J Obstet Gynaecol , vol.106 , pp. 1304-1306
    • Wald, N.J.1    White, N.2    Morris, J.K.3    Huttly, W.J.4    Canick, J.E.5
  • 65
    • 0042266216 scopus 로고    scopus 로고
    • Combining nuchal translucency and serum markers in prenatal screening for Down syndrome in twin pregnancies
    • Wald NJ, Rish S and Hackshaw AK (2003a) Combining nuchal translucency and serum markers in prenatal screening for Down syndrome in twin pregnancies. Prenat Diagn 23,588-592.
    • (2003) Prenat Diagn , vol.23 , pp. 588-592
    • Wald, N.J.1    Rish, S.2    Hackshaw, A.K.3
  • 66
    • 0037704145 scopus 로고    scopus 로고
    • First and second trimester antenatal screening for Down's syndrome: The results of the Serum, Urine and Ultrasound Screening Study (SURUSS)
    • Wald NJ, Rodeck C, Hackshaw AK, Walters J, Chitty L and Mackinson AM (2003b) First and second trimester antenatal screening for Down's syndrome: The results of the Serum, Urine and Ultrasound Screening Study (SURUSS). J Med Screen 10,56-104.
    • (2003) J Med Screen , vol.10 , pp. 56-104
    • Wald, N.J.1    Rodeck, C.2    Hackshaw, A.K.3    Walters, J.4    Chitty, L.5    Mackinson, A.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.