Regulation of airway mucin secretion by MARCKS protein involves the chaperones heat shock protein 70 and cysteine string protein

Proceedings of the American Thoracic Society

Volumn 3, Issue 6, 2006, Pages 493-

  Park, Joungjoa ^a   Fang, Shijing ^a   Adler, Kenneth B ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CYSTEINE STRING PROTEIN; HEAT SHOCK PROTEIN 70; MARCKS PROTEIN; MEMBRANE PROTEIN; MUCIN; SMALL INTERFERING RNA;

CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN SECRETION; RESPIRATORY EPITHELIUM; WESTERN BLOTTING;

BLOTTING, WESTERN; BRONCHI; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MUCINS; NERVE TISSUE PROTEINS; PROTEIN KINASE C; RESPIRATORY MUCOSA;

EID: 33747870492     PISSN: 15463222     EISSN: 15463222     Source Type: Journal    
DOI: 10.1176/appi.ps.57.4.493     Document Type: Conference Paper

References (2)

1. Li Y, Martin LD, Spizz G, Adler KB. MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. J Biol Chem 2001;276:40982-40990.
2. Singer M, Martin LD, Vargaftig BB, Park J, Gruber AD, Li Y, Adler KB. A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. Nat Med 2004;10:193-196.