Phospholipase A2 activity in platelets of patients with primary thrombocythemia

Platelets

Volumn 17, Issue 5, 2006, Pages 332-335

  Vecino, Ana M ^a   Cesar, J M ^a   Navarro, J L ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Arachidonic acid; Phospholipase A2; Platelets; Primary thrombocythemia

Indexed keywords

ARACHIDONIC ACID; CALCIMYCIN; CALCIUM IONOPHORE; CARBON 11; HYDROXYICOSATETRAENOIC ACID; LIPOXYGENASE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; PHOSPHOLIPID; PROSTAGLANDIN SYNTHASE; PROSTANOID; THROMBOXANE A2;

ADULT; AGED; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL LABELING; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; RADIOACTIVITY; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD PLATELETS; EICOSANOIC ACIDS; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOSPHOLIPASES A; PHOSPHOLIPIDS; PLATELET ACTIVATION; PLATELET AGGREGATION; THROMBOCYTHEMIA, HEMORRHAGIC;

EID: 33747759392     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.1080/09537100600746599     Document Type: Article

References (22)

1. Schafer AI. Bleeding and thrombosis in the myeloproliferative disorders. Blood 1984;64:1-12.
2. Wehmeier A, Sudhoff T, Meierkord F. Relation of platelet abnormalities to thrombosis and hemorrhage in chronic myeloproliferative disorders. Semin Thromb Hemost 1997;23:391-402.
3. Spaet TH, Gaynor E, Goldstein ML. Defective platelets in essential thrombocythemia. Arch Intern Med 1969;124:135-141.
4. Murphy S, Davis JL, Walsh PN, Gardner FH. Template bleeding time and clinical hemorrhage in myeloproliferative disease. Arch Intern Med 1978;138:1251-1253.
5. Wu KK. Platelet hyperaggregability and thrombosis in patients with thrombocythemia. Ann Intern Med 1978;88:7-11.
6. Balduini CL, Bertolino G, Noris P, Piletta GC. Platelet aggregation in platelet-rich plasma and whole blood in 120 patients with myeloproliferative disorders. Am J Clin Pathol 1991;95:82-86.
7. Mayordomo O, Carcamo C, Vecino AM, Navarro JL, Cesar JM. Arachidonic acid metabolism in platelets of patients with essential thrombocythaemia. Thromb Res 1995;78:315-321.
8. Irvine RF. How is the level of free arachidonic acid controlled in mammalian cells?. Biochem J 1982;204:3-16.
9. Bills TK, Smith JB, Silver MJ. Selective release of arachidonic acid from the phospholipids of human platelets in response to thrombin. J Clin Invest 1977;60:1-6.
10. Broekman MJ. Stimulated platelets release equivalent amounts of arachidonate from phosphatidylcholine, phosphatidylethanolamine and inositides. J Lipid Res 1986;27:884-891.
11. Murphy S, Peterson P, Iland H, Laszlo J. Experience of the Polycythemia Vera Study Group with essential thrombocythemia: A final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol 1997;34:29-39.
12. Ana M Vecino, Jose L Teruel, Jose L Navarro, Jesus M Cesar. Phospholipase A2 activity in platelets of patients with uremia. Platelets 2002;13:415-418.
13. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-917.
14. Cesar JM, Navarro JL. Arachidonic acid metabolism in platelets stored for 5 days. Br J Haematol 1990;74:294-295.
15. Simon IL, Martin TJ. Platelet thromboxane synthesis and release reaction in myeloproliferative disorders. Haemostasis 1982;11:119-127.
16. Rocca B, Ciabattoni G, Trataglione R, Cortelazzo S, Barbui T, Patrono C, Landolfi R. Increased thromboxane biosynthesis in essential thrombocythemia. Thromb Haemost 1995;74:1225-1230.
17. Rittenhouse-Simmons SE. Activation of human platelet phospholipase C by ionophore A23187 is totally dependant upon cyclooxygenase products and ADP. Biochem J 1984;222:103-110.
18. Borsch HAG, Bartoli F, Asselin J, Dudler T, Kramer RM, Apitz-Castro R, Watson SP, Gelb MH. Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells. J Biol Chem 1998;273:4449-4458.
19. Cesar JM, Vecino AM, Perez-Vaquero M, Navarro JL. Phospholipids determination in platelets, plasma and red cells of patients with myeloproliferative diseases. Eur J Haemat 1993;50:234-236.
20. Nugteren DH. Arachidonate lipoxygenase in blood platelets. Biochim Biophys Acta 1975;380:299-307.
21. Hamberg M, Svensson J, Samuelsson B. Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Prod Natl Acad Sci USA 1975;72:2994-2998.
22. Vane JR. The node of action of aspirin-like drugs. Agents Actions 1978;8:430-431.