Propofol, more than halothane, depresses electroencephalographic activation resulting from electrical stimulation in reticular formation

Acta Anaesthesiologica Scandinavica

Volumn 50, Issue 8, 2006, Pages 993-998

  Antognini, J F ^a,b   Bravo, E ^a   Atherley, R ^a   Carstens, E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electroencephalography; Halothane; Propofol; Reticular formation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; HALOTHANE; PANCURONIUM; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BRAIN CORTEX; CARBON DIOXIDE TENSION; CONTROLLED STUDY; CRANIOTOMY; ELECTROENCEPHALOGRAPHY; ELECTROSTIMULATION; GENERAL ANESTHESIA; INFUSION RATE; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; RETICULAR FORMATION;

ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; HALOTHANE; MALE; MOVEMENT; PROPOFOL; RATS; RETICULAR FORMATION;

EID: 33747735552     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2006.01114.x     Document Type: Article

References (15)

1. Moruzzi G, Magoun HW. Brain stem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1949; 1: 455-73.
2. Orth M, Bravo E, Barter L, Carstens E, Antognini J. Differential effects of halothane and isoflurane on electroencephalographic responses to electrical microstimulation of the reticular formation. Anesth Analg 2006; 102: 1709-14.
3. Orth M, Barter L, Dominguez C, Atherley R, Carstens E, Antognini JF. Halothane and propofol differentially affect electroencephalographic responses to noxious stimulation. Br J Anaesth 2005; 95: 477-84.
4. Antognini JF, Carstens E, Sudo M, Sudo S. Isoflurane depresses electroencephalographic and medial thalamic responses to noxious stimulation via an indirect spinal action. Anesth Analg 2000; 91: 1282-8.
5. Antognini JF, Saadi J, Wang XW, Carstens E, Piercy M. Propofol action in both spinal cord and brain blunts electroencephalographic responses to noxious stimulation in goats. Sleep 2001; 24: 26-31.
6. Jinks SL, Martin JT, Carstens E, Jung SW, Antognini JF. Peri-MAC depression of a nociceptive withdrawal reflex is accompanied by reduced dorsal horn activity with halothane but not isoflurane. Anesthesiology 2003; 98: 1128-38.
7. Fan SZ, Yu HY, Chen YL, Liu CC. Propofol concentration monitoring in plasma or whole blood by gas chromatography and high-performance liquid chromatography. Anesth Analg 1995; 81: 175-8.
8. Ying SW, Goldstein PA. Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABAA receptor chloride channels. Mol Pain 2005; 1: 2.
9. Kitamura A, Marszalec W, Yeh JZ, Narahashi T. Effects of halothane and propofol on excitatory and inhibitory synaptic transmission in rat cortical neurons. J Pharmacol Exp Ther 2003; 304: 162-71.
10. Hentschke H, Schwarz C, Antkowiak B. Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABAA receptor-mediated inhibition. Eur J Neurosci 2005; 21: 93-102.
11. Imas OA, Ropella KM, Ward BD, Wood JD, Hudetz AG. Volatile anesthetics disrupt frontal-posterior recurrent information transfer at gamma frequencies in rat. Neurosci Lett 2005; 387: 145-50.
12. Gregory GA, Eger EI, Munson ES. The relationship between age and halothane requirement in man. Anesthesiology 1969; 30: 488-91.
13. Smith C, McEwan AI, Jhaveri R, et al. The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. Anesthesiology 1994; 81: 820-8.
14. Stoelting RK, Longnecker DE, Eger EI. Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake. Anesthesiology 1970; 33: 5-9.
15. Naguib M, Baker MT, Spadoni G, Gregerson M. The hypnotic and analgesic effects of 2-bromomelatonin. Anesth Analg 2003; 97: 763-8.