Correlation between acute rejection severity and CD8-positive T cells in living related liver transplantation

Transplant Immunology

Volumn 16, Issue 1, 2006, Pages 60-64

  Kubota, Nobuyuki ^a   Sugitani, Masahiko ^a   Takano, Seigo ^b   Sheikh, Aleemuzzaman ^a   Takayama, Tadatoshi ^a   Haga, Hironori ^c   Tanaka, Koichi ^d   Yamabe, Hirohiko ^c  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Sagamihara Kyodo Hospital   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute cellular rejection (ACR); CD4; CD8; Living related liver transplantation (LRLT); Rejection activity index (RAI)

Indexed keywords

ANTIBODY; CD20 ANTIBODY; CD20 ANTIGEN; CD4 ANTIBODY; CD4 ANTIGEN; CD8 ANTIBODY; CD8 ANTIGEN; FORMALDEHYDE; PARAFFIN; UNCLASSIFIED DRUG;

ACUTE GRAFT REJECTION; ADOLESCENT; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; INFANT; LIVER BIOPSY; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; LIVING DONOR; MALE; NEEDLE BIOPSY; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CHILD; CHILD, PRESCHOOL; FEMALE; GRAFT REJECTION; HUMANS; INFANT; LIVER; LIVER TRANSPLANTATION; LIVING DONORS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED;

EID: 33747647455     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2006.03.002     Document Type: Article

References (16)

1. Minamiguchi S., Sakurai T., Fujita S., Okuno T., Haga H., Mino M., et al. Living related liver transplantation: histopathologic analysis of graft dysfunction in 304 patients. Hum Pathol 30 12 (1999) 1479-1487
2. Chen C.L., Fan S.T., Lee S.G., Makuuchi M., and Tanaka K. Living-donor liver transplantation: 12 years of experience in Asia. Transplantation 15;75 3 Suppl (2003) S6-S11
3. Sugawara Y., Makuuchi M., Kaneko J., Ohkubo T., Matsui Y., Imamura H., et al. Living-donor liver transplantation in adults: Tokyo University experience. J Hepatobiliary Pancreat Surg 10 1 (2003) 1-4
4. Demetris A.J., Seaberg E.C., Batts K.P., Ferrel L.D., Ludwig J., Markin R.S., et al. Reliability and predictive value of the National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database nomenclature and grading system for cellular rejection of liver allografts. Hepatology 21 2 (1995) 408-416
5. Demetris A.J., Batts K.P., Dhillon A.P., Fung L.F., Geller S.A., Hart J., et al. Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 25 3 (1997) 658-663
6. Crosbie O.M., Norris S., Hegarty J.E., and O'Farrelly C. T lymphocyte subsets and activation status in patients following liver transplantation. Immunol Invest 27 4-5 (1998) 237-241
7. Norris S., Collins C., Doherty D.G., Smith F., McEntee G., Traynor O., et al. Resident human hepatic lymphocytes are phenotypically different from circulating lymphocytes. J Hepatol 28 1 (1998) 84-90
8. Crosbie O.M., Costtello P.J., O'Farrelly C., and Hegarty J.E. Changes in peripheral blood double-negative T-lymphocyte (CD3+ CD4 - CD8 -) populations associated with acute cellular rejection after liver transplantation. Liver Transpl Surg 4 2 (1998) 141-145
9. The US Muliticenter FK506 Liver Study Group. A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression in liver transplantation. N Engl J Med 331 17 (1994) 1110-1115
10. Shi S.R., Key M.E., and Kalra K.L. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 39 6 (1991) 741-748
11. Williamson S.L., Steward M., Milton I., Parr A., Piggott N.H., Krajewski A.S., et al. New monoclonal antibodies to the T cell antigens CD4 and CD8. Production and characterization in formalin-fixed paraffin-embedded tissue. Am J Pathol 152 6 (1998) 1421-1426
12. Cattoretti G., Pileri S., Parravicini C., Becker M.H., Poggi S., Bifulco C., et al. Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections. J Pathol 171 2 (1993) 83-98
13. McCaughan G.W., Davies J.S., Waugh J.A., Bishop G.A., Hall B.M., Gallagher N.D., et al. A quantitative analysis of T lymphocyte populations in human liver allografts undergoing rejection: the use of monoclonal antibodies and double immunolabeling. Hepatology 12 6 (1990) 1305-1313
14. Ibrahim S., Dawson D.V., Killenberg P.G., and Sanfilippo F. The pattern and phenotype of T-cell infiltration associated with human liver allograft rejection. Human Pathol 24 12 (1993) 1365-1370
15. Dollinger M.M., Howie S.E., Plevris J.N., Graham A.M., Hayes P.C., and Harrison D.J. Intrahepatic proliferation of 'naive' and 'memory' T cells during liver allograft rejection: primary immune response within the allograft. FASEB J 12 11 (1998) 939-947
16. Morales A.R., Nassiri M., Kanhoush R., Vincek V., and Nadji M. Experience with an automated microwave-assisted rapid tissue processing method: validation of histologic quality and impact on the timeliness of diagnostic surgical pathology. Am J Clin Pathol 121 4 (2004) 528-536