Vaccinating healthcare workers against influenza to protect the vulnerable-Is it a good use of healthcare resources?. A systematic review of the evidence and an economic evaluation

Vaccine

Volumn 24, Issue 19, 2006, Pages 4212-4221

  Burls, Amanda ^a   Jordan, Rachel ^a,b   Barton, Pelham ^c   Olowokure, Babatunde ^a,b   Wake, Beverley ^a   Albon, Esther ^a   Hawker, Jeremy ^d  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^c Health Services Management Centre   (United Kingdom)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Economic evaluation; Healthcare workers; Influenza vaccination; Systematic review

Indexed keywords

INFLUENZA VACCINE;

ARTICLE; CLINICAL TRIAL; COST CONTROL; DATA EXTRACTION; DRUG EFFICACY; ECONOMIC ASPECT; ECONOMIC EVALUATION; ERYTHEMA; EUROPE; HEALTH CARE COST; HEALTH CARE PERSONNEL; HEALTH CARE POLICY; HEALTH PROGRAM; HIGH RISK PATIENT; HUMAN; INFLUENZA; INFLUENZA VACCINATION; INJECTION SITE EDEMA; INJECTION SITE PAIN; MORTALITY; PRIORITY JOURNAL; QUALITY CONTROL; SYSTEMATIC REVIEW; UNITED KINGDOM; COST BENEFIT ANALYSIS; DISEASE TRANSMISSION; ECONOMICS; HEALTH CARE PLANNING; REVIEW; UTILIZATION REVIEW; VACCINATION;

COST-BENEFIT ANALYSIS; EUROPE; GREAT BRITAIN; HEALTH PERSONNEL; HEALTH RESOURCES; HUMANS; INFLUENZA VACCINES; INFLUENZA, HUMAN; VACCINATION;

EID: 33747625602     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.12.043     Document Type: Article

References (53)

1. World Health Organisation. Influenza vaccines. WHO position paper. Weekly epidemiological record 2002;28(77):229-40.
2. Van Essen G.A., Palache A.M., Forleo E., and Fedson D.S. Influenza vaccination in 2000: recommendations and vaccine use in 50 developed and rapidly developing countries. Vaccine 21 (2003) 1780-1785
3. Gross C.P., Hermogenes A.W., Sacks H.S., Lau J., and Levandowski R.A. The efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literature. Ann Intern Med 123 5 (1995) 18-27
4. Poole PJ, Cacko E, Wood-Baker RWB, Cates CJ. Influenza vaccine for patients with chronic obstructive pulmonary disease The Cochrane Database of Systematic Reviews 2006; Issue 1, Art no.: CD002733, DOI:10.1002/14651858, CD002733, pub 2.
5. Jordan R., Connock M., Albon E., et al. Universal vaccination of children against influenza: are there indirect benefits to the community?: a systematic review of the evidence. Vaccine 24 (2006) 1047-1062
6. Health Protection Agency. Influenza A outbreak in a community hospital in south east Wales where few healthcare workers had received immunisation, February 2005. CDR Weekly 2005;15(8):Available at http://www.hpa.org.uk/cdr.
7. Kroneman M., Paget W.J., and Van Essen G. Influenza vaccination in Europe: an inventory of strategies to reach target populations and optimize vaccination uptake. Eurosurveillance 8 6 (2003) 130-138
8. Ukoumunne O.C., Guilliford M.C., Chinn S., Sterne J.A.C., and Burney P.G.J. Methods for evaluation area-wide and organisational-based interventions in health and health care: a systematic review. Health Technol Assess 3 5 (1999)
9. York: Centre for Reviews and Dissemination. Undertaking systematic reviews of research on effectiveness. CRD's guidance for those carrying out or commissioning reviews 2001. CRD Report Number 4 (2nd edition).
10. Carman W.F., Elder A.G., Wallace L.A., et al. Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomised controlled trial. Lancet 355 9198 (2000) 93-97
11. Potter J., Stott D.J., Roberts M.A., et al. Influenza vaccination of health care workers in long-term-care hospitals reduces the mortality of elderly patients. J Infect Dis 175 1 (1997) 1-6
12. Wilde J.A., McMillan J.A., Serwint J., Butta J., O'Riordan M.A., and Steinhoff M.C. Effectiveness of influenza vaccine in health care professionals: a randomized trial. JAMA 281 10 (1999) 908-913
13. Saxén H., and Virtanen M. Randomized, placebo-controlled double blind study on the efficacy of influenza immunization on absenteeism of health care workers. Pediatr Infect Dis J 18 9 (1999 Sep) 779-783
14. Weingarten S., Staniloff H., Ault M., Miles P., Bamberger M., and Meyer R.D. Do hospital employees benefit from the influenza vaccine? A placebo-controlled clinical trial. J Gen Intern Med 3 1 (1988) 32-37
15. Dey P., Halder S., Collins S., Benons L., and Woodman C. Promoting uptake of influenza vaccination among health care workers: a randomized controlled trial. J Public Health Med 23 4 (2001) 346-348
16. Tannenbaum T.N., Thomas D., Baumgarten M., Saintonge F., and Roban I. Evaluation of an influenza vaccination program for nursing home staff. Can J Public Health 84 1 (1993) 60-62
17. Cooper E., and O'Reilly M. A novel staff vaccination strategy [letter]. Infect Control Hosp Epidemiol 23 5 (2002) 232-233
18. Harbarth S., Siegrist C., Schira J., Wunderli W., and Pittet D. Influenza immunization: improving compliance of healthcare workers. Infect Control Hosp Epidemiol 19 5 (1998) 337-342
19. Thomas D.R., Winsted B., and Koontz C. Improving neglected influenza vaccination among healthcare workers in long-term care. J Am Geriatr Soc 41 9 (1993) 928-930
20. Heimberger T., Chang H.G., Shaikh M., Crotty L., Morse D., and Birkhead G. Knowledge and attitudes of healthcare workers about influenza: why are they not getting vaccinated?. Infect Control Hosp Epidemiol 16 7 (1995) 412-415
21. Christian M.A. Influenza and hepatitis B vaccine acceptance: a survey of health care workers. Am J Infect Control 19 4 (1991) 177-184
22. Ganguly R., Russell D.W., Yangco B.V., Chmel H., Cameron D.J., and Sinnott J. Influenza vaccination status among health care professionals for prevention of nosocomial infection to hospitalized elderly patients. Serodiagnosis Immunother Infect Dis 4 4 (1990) 309-315
23. Nafziger D.A., and Herwaldt L.A. Attitudes of internal medicine residents regarding influenza vaccination. Infect Control Hosp Epidemiol 15 (1994) 32-35
24. Nichol K.L., and Hauge M. Influenza vaccination of healthcare workers. Infect Control Hosp Epidemiol 18 3 (1997) 189-194
25. Stephenson I., Roper J.P., and Nicholson K.G. Healthcare workers and their attitudes to influenza vaccination. Commun Dis Public Health 5 3 (2002) 247-252
26. Watanakunakorn C., Ellis G., and Gemmel D. Attitude of healthcare personnel regarding influenza immunization. Infect Control Hosp Epidemiol 14 1 (1993) 17-20
27. DeAngelis C.D., Raszka W.V., Chamberlin S.M., and Zimmerman J.L. Influenza immunization rates among pediatric health care providers. Arch Pediatr Adolesc Med 150 12 (1996) 1311-1313
28. Demicheli V., Jefferson T., Rivetti D., and Deeks J. Prevention and early treatment of influenza in health adults. Vaccine 18 (2000) 957-1030
29. Parlevliet W., de Borgie C., Frijstein G., and Guchelaar H.-K. Cost-benefit analysis of vaccination against influenza of employees from an academic medical centre. Dis Manage Health Outcomes 10 9 (2002) 579-587
30. Yassi A., Kettner J., Hammond G., Cheang M., and McGill M. Effectiveness and cost-benefit of an influenza vaccination program for health care workers. Can J Infect Dis 2 3 (1991) 101-108
31. Kumpulainen V., and Makela M. Influenza vaccination among healthy employees: a cost-benefit analysis. Scand J Infect Dis 29 2 (1997) 181-185
32. Bridges C.B., Thompson W.W., Meltzer M.I., et al. Effectiveness and cost-benefit of influenza vaccination of healthy working adults: a randomized controlled trial. JAMA 284 13 (2000) 1655-1663
33. Akazawa M., Sindelar J.L., and Paltiel A.D. Economic costs of influenza-related work absenteeism. Value Health 6 2 (2003) 107-115
34. Levy E. French economic evaluations of influenza and influenza vaccination. Pharmacoeconomics 9 Suppl. 6 (1996)
35. Lee P.Y., Matchar D.B., Clements D.A., Huber J., Hamilton J.D., and Peterson E.D. Economic analysis of influenza vaccination and antiviral treatment for healthy working adults. Ann Intern Med 137 4 (2002) 225-231
36. Fitzner K.A., Shortridge K.F., McGhee S.M., and Hedley A.J. Cost-effectiveness study on influenza prevention in Hong Kong. Health Policy 56 3 (2001) 215-234
37. Nichol K.L. Cost-benefit analysis of a strategy to vaccinate healthy working adults against influenza. Arch Intern Med 161 5 (2001) 749-759
38. Nichol K.L., Lind A., Margolis K.L., et al. The effectiveness of vaccination against influenza in healthy, working adults. N Engl J Med 333 14 (1995) 889-893
39. Burckel E., Ashraf T., Sousa Filho J.P., et al. Economic impact of providing workplace influenza vaccination. A model and case study application at a Brazilian pharma-chemical company. Pharmacoeconomics 16 5, Part 2 (1999) t-76
40. Campbell D.S., and Rumley M.H. Cost-effectiveness of the influenza vaccine in a healthy, working-age population. J Occup Environ Med 39 5 (1997) 408-414
41. Dille J.H. A worksite influenza immunization program. Impact on lost work days, health care utilization, and health care spending. AAOHN J 47 7 (1999) 301-309
42. Wood S.C., Alexseiv A., and Nguyen V.H. Effectiveness and economical impact of vaccination against influenza among a working population in Moscow. Vaccine 17 Suppl. 7 (1999)
43. Netten A, Curtis L. Unit costs of health & social care 2003. Available from URL: http://www.pssru.ac.uk/pdf/uc2003/uc2003.pdf. Accessed 20/10/2004.
44. Department of Health. Community Care Statistics 2001-Private Nursing homes, hospitals and clinics, 2002. http://www.publications.doh.gov.uk/public/sb0209.htm. Accessed November 2004.
45. Wood P., and Castleden M. Dependency, quality and staffing of institutions for elderly people. Health Trends 25 3 (1993) 97-101
46. British Medical Association & Royal Pharmaceutical Society of Great Britain. British National Formulary. http://www.bnf.org/bnf/bnf/current/doc/112803.htm 2004. Accessed May 17, 2004.
47. National Institute for Clinical Excellence. Guide to the methods of technology appraisal 2004. http://www.nice.org.uk/pdf/TAP_Methods.pdf. Accessed October 2004.
48. Raines J.E., and Wight J. The mortality experience of people admitted to nursing homes. J Public Health Med 24 3 (2002) 184-189
49. Information & Statistics Division. The National Health Service in Scotland. Scottish Health Resource Utilisation Groups National Report 1999. http://www.show.scot.nhs.uk/isdonline/Scottish_Health_Statistics/subject /SHRUGs/shrugs99.pdf 2000. Accessed November 2, 2004.
50. Office of National Statistics. Interim life tables-England & Wales (females) 2004. http://www.gad.gov.uk/Life_Tables/docs/wltewf0103.xls. Accessed 20/10/2004.
51. Office of National Statistics. Interim Life Tables-England & Wales (males) 2004. http://www.gad.gov.uk/Life_Tables/docs/wltewm0103.xls. Accessed 20/10/2004.
52. Elgohari S, Joseph CA, Goddard NL. Three years experience of monitoring influenza vaccine uptake in healthcare workers in acute hospital trusts in England 2001/02-2003/04. Five Nations Health Protection Conference 2004.
53. Poland G.A., Tosh P., and Jacobson R.M. Requiring influenza vaccination for health care workers: seven truths we must accept. Vaccine 23 17-18 (2005) 2251-2255