Effect of tandem forms of DAF(CD55) on complement-mediated xenogeneic cell lysis

Xenotransplantation

Volumn 13, Issue 5, 2006, Pages 433-439

  Miyagawa, Shuji ^a   Fukuta, Daisuke ^a,b   Kitano, Etsuko ^a   Kobayashi, Chizuko ^a   Fumimoto, Yuichi ^a   Shirasu, Akio ^b   Hattori, Hiroyuki ^b   Shirakura, Ryota ^a   Fukuzawa, Masahiro ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Nipro Corporation   (Japan)

Author keywords

C3 deposition; CHO cell; Complement; DAF; Tandem form

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENTARY DNA; DECAY ACCELERATING FACTOR;

ANIMAL CELL; ARTICLE; CHO CELL; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEMENT DEPOSITION; CONTROLLED STUDY; ENDOTHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; SWINE; TRANSGENIC ANIMAL; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD55; CHO CELLS; COMPLEMENT ACTIVATION; CONSENSUS SEQUENCE; CRICETINAE; CYTOTOXICITY, IMMUNOLOGIC; DNA, COMPLEMENTARY; FLOW CYTOMETRY; REPETITIVE SEQUENCES, NUCLEIC ACID; SWINE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 33747621840     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2006.00331.x     Document Type: Article

References (28)

1. NICHOLSON-WELLER A, BURGE J, AUSTEN KF. Purification from guinea pig erythrocyte stroma of a decay-accelerating factor for the classical c3 convertase, C4b,2a. J Immunol 1981; 127: 2035.
2. COZZI E, LANGFORD GA, RICHARDS A et al. Expression of human decay accelerating factor in transgenic pigs. Transplant Proc 1994; 26: 1402.
3. MCCURRY KR, KOOYMAN DL, ALVARADO CG et al. Human complement regulatory proteins protect swine-toprimate cardiac xenografts from humoral injury. Nat Med 1995; 1: 423.
4. FODOR WL, WILLIAMS BL, MATIS LA et al. Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection. Proc Natl Acad Sci U S A 1994; 91: 11153.
5. ROSENGARD AM, CARY NR, LANGFORD GA, TUCKER AW, WALLWORK J, WHITE DJ. Tissue expression of human complement inhibitor, decay-accelerating factor, in transgenic pigs. A potential approach for preventing xenograft rejection. Transplantation 1995; 59: 1325.
6. SEYA T, TURNER JR, ATKINSON JP. Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b. J Exp Med 1986; 163: 837.
7. COOPER DK. Clinical xenotransplantion - how close are we? Lancet 2003; 362: 557.
8. MURAKAMI H, NAGASHIMA H, TAKAHAGI Y et al. Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter. Mol Reprod 2002; 61: 302.
9. KUWAKI K, TSENG YL, DOR FJ et al. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med 2005; 11: 29.
10. TAKAHAGI Y, FUJIMURA T, MIYAGAWA S et al. Production of alpha 1,3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III. Mol Reprod Dev 2005; 71: 331.
11. MIYAGAWA S, SHIRAKURA R, IWATA K et al. Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAF hybrid, on complement-mediated swine endotherial cell lysis. Transplantation 1994; 58: 834.
12. MIYAGAWA S, MIKATA S, SHIRAKURA et al. C5b-8 step lysis of swine endothelial cells by human complement and functional feature of transfected CD59. Scand J Immunol 1996; 43: 361.
13. COZZI E, LANGFORD GA, WRIGHT L et al. Comparative analysis of human DAF expression in the tissues of transgenic pigs and man. Transplant Proc 1995; 27: 319.
14. MAKRIDES SC, SCESNEY SM, FORD PJ et al. Cell surface expression of the C3b/C4b receptor (CR1) protects Chinese hamster ovary cells from lysis by human complement. J Biol Chem 1992; 267: 24754.
15. FUKUTA D, MIYAGAWA S, KUBO T et al. Effect of hybrid complement regulatory proteins on xenogeneic cells. Biochem Biophys Res Commun 2003; 306: 476.
16. NIWA H, YAMAMURA K, MIYAZAKI J. Efficient selection for high-expression transfectants with a novel eukariotic vector. Gene 1991; 108: 193.
17. FUKUTA D, MIYAGAWA S, YAMADA M et al. Effect of various forms of C1 esterase inhibitor (C1-INH) and DAF on complement mediated xenogeneic cell lysis. Xenotransplantation 2003; 10: 132.
18. DALMASSO AP, VERCELLOTTI GM, FISCHEL RJ et al. Mechanism of complement activation in the hyperacute rejection of porcine organs transplanted into primate recipients. Am J Pathol 1992; 140: 1157.
19. KOMODA H, MIYAGAWA S, OMORI T et al. Survival of adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) in cynomolgus monkeys. Xenotransplantation 2005; 12: 209.
20. FINBERG RW, WHITE W, NICHOLSON-WELLER A. Decay-accelerating factor expression on either effector or target cells inhibits cytotoxicity by human natural killer cells. J Immunol 1992; 149: 2055.
21. CARAGINE TA, IMAI M, FREY AB, TOMLINSON S. Expression of rat complement control protein Crry on tumor cells inhibits rat natural killer cell-mediated cytotoxicity. Blood 2002; 100: 3304.
22. MIYAGAWA S, KUBO T, MATSUNAMI K et al. Delta-short consensus repeat 4-decay accelerating factor (DAF: CD55) inhibits complement-mediated cytolysis but not NK cell-mediated cytolysis. J Immunol 2004; 173: 3945.
23. COYNE KE, HALL SE, THOMPSON S et al. Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor. J Immunol 1992; 149: 2906.
24. KUTTNER-KONDO LA, MITCHELL L, HOURCADE DE, MEDOF ME. Characterization of the active sites in decay-accelerating factor. J Immunol 2001; 167: 2164.
25. MIYAGAWA S, MATSUNAMI K, YOSHITATSU M et al. Attempts to prepare suitable complement regulatory molecules for clinical xenotransplantation. J Card Surg 2001; 16: 429.
26. COWN P, ROUSSEL JC, MORAN C, D'APICE A. Characteruzation of pig thrombomodulin and its interaction with the human protein C anticoagulant pathway. Xenotransplantation 2005; 12: 382.
27. MIYAGAWA S, YAMADA M, MATSUNAMI K et al. A synthetic dDAF (CD55) gene based on optimal codon usage for transgenic animals. J Biochem 2001; 129: 795.
28. CLISSOLD PM, EBLING HJ, LACHMAN PJ. Construction, expression and function analysis of a glycolipid-linked form of CR1. Eur J Immunol 1993; 23: 2346.