Repression of stimulated calcitonin gene-related peptide secretion by topiramate

Headache

Volumn 46, Issue 8, 2006, Pages 1291-1295

  Durham, Paul L ^a   Niemann, Christine ^a   Cady, Roger ^b  

^a MISSOURI STATE UNIVERSITY   (United States)

^b HEADACHE CARE CENTER   (United States)

Author keywords

CGRP; Migraine; Neurons; Nitric oxide; Protons; Trigeminal

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; POTASSIUM CHLORIDE; PROTON; TOPIRAMATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFICACY; MIGRAINE; NOCICEPTION; NONHUMAN; PH; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN SECRETION; RADIOIMMUNOASSAY; RAT; SENSORY NERVE; TRIGEMINAL NERVE; TRIGEMINUS GANGLION;

ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUCTOSE; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE DONORS; PENICILLAMINE; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; TRIGEMINAL GANGLION;

EID: 33747606732     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2006.00538.x     Document Type: Article

References (12)

1. Goadsby P, Lipton R, Ferrari M. Migraine - Current understanding and treatment. N Engl J Med. 2002; 346:257-270.
2. Olesen J, Diener H, Husstedt I, et al. Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Eng J Med. 2004;350:1104-1110.
3. Silberstein S. Topiramate in migraine prevention. Headache. 2005;45(Suppl 1):S57-S65.
4. Brandes JL, Saper JR, Diamond M, et al. Topiramate for migraine prevention: A randomized controlled trial. JAMA. 2004;291:965-973.
5. Silberstein SD, Neto W, Schmitt J, Jacobs D. Topiramate in migraine prevention: Results of a large controlled trial. Arch Neurol. 2004;61:490-495.
6. Durham P, Russo A. Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons. J Neurosci. 2003;23:807-815.
7. Williamson D, Hargreaves R. Neurogenic inflammation in the context of migraine. Microsc Res Tech. 2001;53:167-178.
8. Storer R, Goadsby P. Topiramate inhibits trigeminovascular neurons in the cat. Cephalalgia. 2004;24:1049-1056.
9. Akerman S, Goadsby P. Topiramate inhibits trigeminovascular activation: An intravital microscopy study. Br J Pharmacol. 2005;146:7-14.
10. Iversen H, Olesen J. Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs. Cephalalgia. 1996;16:412-418.
11. Cutrer F. Antiepileptic drugs: How they work in headache. Headache. 2001;41(Suppl 1):S3-S10.
12. Voilley N. Acid-sensing ion channels (ASICs): New targets for the analgesic effects of non-steroid antiinflammatory drugs (NSAIDs). Curr Drug Targets Inflamm Allergy. 2004;3:71-79.