Testing and risk assessment of persistent and bioaccumulating chemical substances - Improvements within REACH?

Human and Ecological Risk Assessment

Volumn 12, Issue 4, 2006, Pages 782-805

  Breitholtz, Magnus ^a   Eriksson, Johan ^a   Green, Nicholas ^a   Rudén, Christina ^b  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

CAS 32534 81 9; PBT; PentaBDE; REACH; Risk assessment; vPvB

Indexed keywords

EID: 33747600159     PISSN: 10807039     EISSN: 15497860     Source Type: Journal    
DOI: 10.1080/10807030600801618     Document Type: Article

References (40)

1. AMAP (Arctic Monitoring and Assessment Programme). 2002. Arctic Pollution. AMAP, Oslo, Norway
2. Andersson T and Förlin L. 1992. Regulation of the cytochrome-P450 enzyme-system in fish. Aquat Toxicol 24(1-2):1-19
3. Baird DJ. 1992. Predicting population responses to pollutants: A reply to Forbes and Depledge. Funct Ecol 6:616-9
4. Barnthouse LW. 1993. Population-level effects. In: Ecological Risk Assessment. Lewis Publishers, Chelsea, MI, USA
5. Belfiore NM and Anderson SL. 2001. Effects of contaminants on genetic patterns in aquatic organisms: A review. Mutat Res 289:97-122
6. Block D, Bejarano AC, and Chandler GT. 2003. Ecdysteroid concentrations through various life-stages of the meiobenthic copepod, Amphiascus tenuiremis and the benthic estuarine amphipod, Leptocheirus plumulosus. Gen Comp Endocrinol 132:151-60
7. m) of the harpacticoid copepod Nitocra spinipes. Aquat Toxicol 64:85-96
8. Breitholtz M, Hill C, and Bengtsson B.-E. 2001. Toxic substances and reproductive disorders in Baltic fish and crustaceans. Ambio 30(4-5):210-6
9. Calow P. 1996. Ecology in ecotoxicology: Some possible 'rules of thumb,' 5-12. In: Baird D J, Maltby L, Greig-Smith PW, et al. (eds), ECOtoxicology: Ecological Dimensions. Chapman and Hall, SETAC Press Series, Cambridge, UK
10. CEU (Council of the European Union). 2006. Presidency Proposal for a regulation of the European Parliament and of the council concerning the Registration, Evaluation, Authorisation and Restrictions of Chemicals (REACH), establishing a European Chemicals Agency and amending Directive 1999/45/EC and Regulation (EC) {on Persistent Organic Pollutants}. 15921/1/05 REV 1, Brussels, 9 March 2006, available at http://register.consilium.eu.int
11. Chandler GT and Green AS. 2001. Developmental stage-specific life-cycle bioassay for assessment of sediment-associated toxicant effects on benthic copepod production. Environ Toxicol Chem 20(1):171-8
12. Cox P and Efthymiou P. 2003. Directive 2003/11/EC of the European Parliament and of the Council of February 6, 2003 amending for the 24th time Council Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (pentabromodipphenyl ether, octabromodiphenyl ether). Official J European Union L42:45-6
13. Cunningham AR and Rosenkranz HS. 2001. Estimating the extent of the health hazard posed by high production volume chemicals. Environ Health Perspect 109(9):953-6
14. Daniels RE and Allen JD. 1981. Life table evaluation of chronic exposure to a pesticide. Can J Fish Aquat Sci 38(5):485-94
15. ECB (European Chemicals Bureau). 2001. European Union Risk Assessment Report for Diphenyl ether, pentabromo deriv. European Chemicals Bureau, European Commission joint research centre. Final report August 2000. Available in full text at www.ecb.jrc.it
16. EC (European Commission). 2001. "White Paper-Strategy for a Future Chemicals Policy" Brussels, 27.2.2001 Com(2001) 88 final. Available at http://europa.eu.int
17. EC (European Commission). 2003b. Technical Guidance Document in Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for Existing Substances and Directive 98/8/EC of the European Parliament and of the Council Concerning the Placing of Biocidal Products on the Market. Part II, printed in Italy. Available at ecb.jrc.it
18. ECETOC. 2003. Persistence of chemicals in the environment. JACC No. 90. Brussels. European Center for Ecotoxicology and Toxicology of Chemicals. Brussels, Belgium
19. Eriksson P, Jacobson E, and Fredriksson A. 1998. Developmental Neurotoxicity of Brominated Flame Retardants, Polybrominated Diphenyl Ethers and Tetrabromobisphenol A. Organohalogen Compounds 35:375-7
20. European Council Directive 67/548 of 27 June 1967 on the Approximation of Laws, Regulations and Administrative Provisions Relating to the Classification, Packaging and Labeling of Dangerous Substances, Official Journal of the European Communities 196:1-5
21. Forbes VE and Calow P. 2002. Extrapolation in ecological risk assessment: Balancing pragmatism and precaution in chemical controls legislation. Bioscience 52(3):249-57
22. Forbes TL, Forbes VE, Giessing A, et al. 1998. Relative role of pore water versus ingested sediment in bioavailability of organic contaminants in marine sediments. Environ Toxicol Chem 17(12):2453-62
23. Gatermann R, Biselli S, Hühnerfoss H, et al. 2002. Synthetic musks in the environment. Part 1: Species-dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels. Arch Environ Contam Toxicol 42:437-46
24. Gorokhova E and Kyle M. 2002. Analysis of nucleic acids in Daphnia: Development of methods and ontogenetic variations in RNA-DNA content. J Plankton Res 24(5):511-22
25. Green N and Bergman Å. 2004. Screening for reactivity and persistence. In: Hansson SO and Rudén C (eds), Better Chemicals Control Within REACH. Printed by US-AB, Stockholm, Sweden
26. Holm G, Norrgren L, Andersson T, et al. 1993. Effects of exposure to food contaminated with PBDE, PCN or PCB on reproduction, liver morphology and cytochrome P450 activity in the three-spined stickleback, Gasterosteus aculeastus. Aquat Toxicol 27:33-50
27. Ikonomou MG, Rayne S, Fischer M, et al. 2002. Occurrence and congener profiles of polybrominated diphenyl ethers (PBDEs) in environmental samples from coastal British Columbia, Canada. Chemosphere 46:649-63
28. Ingersoll CG, Hutchinson TH, Crane M. et al. 1999. Laboratory tests for evaluating potential effects of endocrine disrupting Compounds. In: de Fur PJ, Crane M, Ingersoll CG, et al. (eds.), Endocrine Disruption in Invertebrates, pp 107-9. SETAC Technical Publication, Brussels, Belgium
29. IPCS (International Programme on Chemica Safety). 1994. Brominated Diphenyl Ethers. WHO Environmental Health Criteria 162, Geneva, Switzerland
30. Kwok ESC and Atkinson R. 1995. Estimation of hydroxyl radical reaction rate constants for gas-phase organic compounds using a structure-reactivity relationship: An update. Atmos Environ 29(14):1685-95
31. Larson RA and Weber EJ. 1994. Reaction Mechanisms in Environmental Organic Chemistry. CRC Press, Boca Raton, FL, USA
32. Norrgren L, Andersson T, and Björk M. 1993. Liver morphology and cytochrome P450 activity in fry of rainbow trout after microinjection of lipid-soluble xenobiotics in the yolk-sac embryos. Aquat Toxicol 26:307-16
33. OECD (Organisation for Economic Co-operation and Development). 1998. Detailed Review Paper on Aquatic Testing Methods for Pesticides and Industrial Chemicals (Part 1: Report), OECD Series on Testing and Assessment (No. 11). Paris, France
34. OECD (Organisation for Economic Co-operation and Development). 2000. Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures. OECD Series on Testing and Assessment (No. 23), Paris, France
35. Roex EWM, van Gestel CAM, van Wezel AP, et al. 2000. Ratios between acute aquatic toxicity and effects on population growth rates in relation to toxicant mode of action. Environ Toxicol Chem 19(3):685-93
36. Rudén C. 2002. From Data to Decision. A Case Study of Controversies in Cancer Risk Assessment. Doctoral thesis. Karolinska University Press, Stockholm, Sweden
37. Sellström U. 1999. Determination of Some Polybrominated Flame Retardants in Biota, Sediment and Sewage Sludge. Ph D. Dissertation. Stockholm University, Stockholm
38. Tittlemier SA, Halldorson T, Stearn GA, et al. 2002. Vapour pressures, aqueous solubilities, and Henry's law constants of some brominated flame retardants. Environ Toxicol Chem 21(9):1804-10
39. van Leeuwen CJ and Hermens JLM. 1995. Risk Assessment of Chemicals: An Introduction. Kluwer Academic Publishers, Dordrecht, The Netherlands
40. Wallberg P, Bergqvist P-A, and Andersson A. 1997. Potential importance of protozoan grazing on the accumulation of polychlorinated biphenyls (PCBs) in the pelagic food web. Hydrobiologia 357(1):53-62