Improved industrial syntheses of penciclovir and famciclovir using N2-acetyl-7-benzylguanine and a cyclic side chain precursor

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 4-6, 2006, Pages 625-634

  Torii, Takayoshi ^a   Yamashita, Keizo ^a   Kojima, Mitsuhiko ^a   Suzuki, Yumiko ^a   Hijiya, Toyoto ^a   Izawa, Kunisuke ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Famciclovir; Industrial synthesis; Penciclovir

Indexed keywords

6,6 DIMETHYL 5,7 DIOXASPIRO[2.5]OCTANE 4,8 DIONE; ACETOACETIC ACID DERIVATIVE; FAMCICLOVIR; GUANINE DERIVATIVE; N2 ACETYL 7 BENZYLGUANINE; PENCICLOVIR; UNCLASSIFIED DRUG;

ALKYLATION; ANALYTIC METHOD; ANTIVIRAL ACTIVITY; ARTICLE; DEBENZYLATION; DRUG INDUSTRY; DRUG SYNTHESIS; PROCESS DESIGN; PRODUCT RECOVERY;

2-AMINOPURINE; ACYCLOVIR; ANTIVIRAL AGENTS; GUANINE; MOLECULAR STRUCTURE; PRODRUGS;

EID: 33747590739     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600686279     Document Type: Article

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