High accumulation of bioactive peptide in transgenic rice seeds by expression of introduced multiple genes

Plant Biotechnology Journal

Volumn 4, Issue 5, 2006, Pages 499-510

  Wakasa, Yuhya ^a   Yasuda, Hiroshi ^a   Takaiwa, Fumio ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

Author keywords

Binary vector; Bioactive peptide; Endosperm specific expression; Glutelin; MultiSite Gateway System; Transgenic rice

Indexed keywords

LACTOSTATIN; OLIGOPEPTIDE; PEPTIDE; PRIMER DNA;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; GENE; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PLANT GENE; PLANT SEED; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRENATAL DEVELOPMENT; RICE; SEQUENCE HOMOLOGY; TRANSGENIC PLANT; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; GENES, PLANT; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; ORYZA SATIVA; PEPTIDES; PLANTS, GENETICALLY MODIFIED; SEEDS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33747589432     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2006.00199.x     Document Type: Article

References (25)

1. Arai, S., Osawa, T., Ohigashi, H., Yoshikawa, M., Kaminogawa, S., Watanabe, M., Ogawa, T., Okubo, K., Watanabe, S., Nishino, H., Shinohara, K., Esashi, T. and Hirahara, T. (2001) A mainstay of functional food science in Japan - history, present status, and future outlook. Biosci. Biotechnol. Biochem. 65, 1-13.
2. Gallie, D.R. (1998) Controlling gene expression in transgenics. Curr. Opin. Plant Biol. 1, 166-172.
3. Goff, S.A., Ricke, D., Lan, T.H., Presting, G., Wang, R., Dunn, M., Glazebrook, J., Sessions, A., Oeller, P., Varma, H., Hadley, D., Hutchison, D., Martin, C., Katagiri, F., Lange, B.M., Moughamer, T., Xia, Y., Budworth, P., Zhong, J., Miguel, T., Paszkowski, U., Zhang, S., Colbert, M., Sun, W.L., Chen, L., Cooper, B., Park, S., Wood, T.C., Mao, L., Quail, P., Wing, R., Dean, R., Yu Y., Zharkikh, A., Shen, R., Sahasrabudhe, S., Thomas, A., Cannings, R., Gutin, A., Pruss, D., Reid, J., Tavtigian, S., Mitchell, J., Eldredge, G., Scoll, T., Miller, R.M., Bhatnagar, S., Adey, N., Rubano, T., Tusneem, N., Robinson, R., Feldhaus, J., Macalma, T., Oliphant, A. and Briggs, S. (2002) A draft sequence of the rice genome (Oriza sativa L. ssp. Japonica). Science, 296, 92-100.
4. Goto, F., Yoshihara, T., Shigemoto, N., Toki, S. and Takaiwa, F. (1999) Iron fortification of rice seed by the soybean ferritin gene. Nat. Biotechnol. 17, 282-286.
5. Hartley, J.L., Temple, G.F. and Brasch, M.A. (2000) DNA cloning using in vitro site-specific recombination. Genome Res. 10, 1788-1795.
6. Hiei, Y., Komai, T. and Kubo, T. (1998) Agrobacterium-mediated transformation. In Molecular Biology of Rice (Shimamoto, K., ed.), pp. 235-256. Tokyo: Springer.
7. Iida, S., Kusaba, M. and Nishio, T. (1997) Mutants lacking glutelin subunits in rice: mapping and combination of mutated glutelin. Theor. Appl. Genet. 94, 177-183.
8. Karimi, M., Meyer, B. and Hilson, P. (2005) Modular cloning in plant cells. Trends Plant Sci. 10, 103-105.
9. Larrick, J.M. and Thomas, D.W. (2001) Production proteins in transgenic plants and animals. Curr. Opin. Plant Biol. 12, 411-418.
10. Matoba, N., Yamada, Y., Usui, H., Nakagiri, R. and Yoshikawa, M. (2001) Designing potent derivatives of Ovokinin (2-7), an antihypertensive peptide derived from Ovalbumin. Biosci. Biotechnol. Biochem. 65, 736-739.
11. Matzke, A.J.M. and Matzke, M.A. (1998) Position effects and epigenetic silencing of plant transgenes. Curr. Opin. Plant Biol. 1, 142-148.
12. Mitsukawa, N., Hayashi, H., Yamamoto, K., Kidzu, K., Konishi, R., Masumura, T. and Tanaka, K. (1998) Molecular cloning of a novel glutelin cDNA from rice seeds. Plant Biotechnol. 15, 205-211.
13. Nagaoka, S., Futamura, Y., Miwa, K., Awano, T., Yamauchi, K., Kanamaru, Y., Kojima, K. and Kuwata, T. (2001) Identification of novel hypocholesterolemic peptides derived from bovine milk β-lactoglobulin. Biochem. Biophys. Res. Commun. 281, 11-17.
14. Onishi, K., Matoba, N., Yamada, Y., Doyama, N., Maruyama, N., Utsumi, S. and Yoshikawa, M. (2004) Optimal designing of β-conglycinin to genetically incorporate RPLKPW, a potent antihypertensive peptide. Peptides, 25, 37-43.
15. Qu, L. and Takaiwa, F. (2004) Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. Plant Biotechnol. J. 2, 113-125.
16. Spiker, S. and Thompson, W.F. (1996) Nuclear matrix attachment regions and transgene expression in plants. Plant Physiol. 110, 15-21.
17. Sugita, K., Endo-Kasahara, S., Tada, Y., Yang, L., Yasuda, H., Hayashi, Y., Jomori, T., Ebinuma, H. and Takaiwa, F. (2005) Genetically modified rice seeds accumulating GLP-1 analogue stimulate insulin secretion from a mouse pancreatic beta-cell line. FEBS Lett. 579, 1085-1088.
18. Tada, Y., Utsumi, S. and Takaiwa, F. (2003) Foreign gene products can be enhanced by introduction into storage protein mutants. Plant Biotechnol. J. 1, 411-422.
19. Takagi, F., Saito, S., Yang, L., Nagaoka, S., Nishizawa, N. and Takaiwa, F. (2005) Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine. Plant Biotechnol. J. 3, 521-533.
20. Takaiwa, F., Kikuchi, S. and Oono, K. (1987) A rice glutelin gene family - a major type of glutelin mRNA can be divided into two classes. Mol. Gen. Genet. 208, 15-22.
21. Takaiwa, F., Oono, K., Wing, D. and Kato, A. (1991) Sequence of three members and expression of new major subfamily of glutelin gene of rice. Plant. Mol. Biol. 17, 875-885.
22. Takaiwa, F., Ogawa, M. and Okita, T.W. (1999) Rice glutelins. In Seed Proteins (Shewry, P.R. and Casey, R., eds), pp. 401-425. Dordrecht: Kluwer Academic Publishers.
23. Yang, L., Tada, Y., Yamamoto, P.M., Zhao, H., Yoshikawa, M. and Takaiwa, F. (2006) A transgenic-rice seed accumulating an antihypertensive peptide reduces the blood pressure of spontaneously hypertensive rats. FEBS left.
24. Yasuda, H., Tada, Y., Hayashi, Y., Jomori, T. and Takaiwa, F. (2005) Expression of the small peptide GLP-1 in transgenic plants. Transgenic Res. 14, 677-684.
25. Yasuda, H., Hayashi, Y., Jomori, T. and Takaiwa, F. (2006) The correlation between expression and localization of a foreign gene product in rice endosperm. Plant Cell Physiol. in press.