Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone

American Journal of Physiology

Volumn 270, Issue 2 PART 1, 1996, Pages

  McDonough, Alicia A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Gene expression; Llc pk1; Proximal tubule; Sodium hydrogen exchange

Indexed keywords

EID: 33747581461     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. 3 cotransporter in metabolic acidosis and alkalosis. J. Clin. Invest. 80:308-315, 1987.
2. Azuma, K. K., C. B. Hensley, M.-J. Tang, and A. A. McDonough. Thyroid hormone specifically regulates skeletal muscle Na,K-ATPase 2 and 2 isoforms. Am. J. Physioi. 265 (Cell Physiol. 34): C680-C687, 1993.
3. Azuma, K. K., and A. A. McDonough. The expression and regulation of NHE-3 in rat proximal tubule by thyroid hormone (Abstract). J. Am. Soc. Nephrol. 4: 862, 1993.
4. Balkovetz, D. F., D. Wang, R. Chambrey, and D. G. Warnock. A polyclonal antibody against an NHE-3 peptide labels an 83 kDa protein in rat brush border membrane vesicles (Abstract). J. Am. Soc. Nephrol. 4: 831, 1993.
5. + exchanger isoform of renal brush border. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F736-F742, 1993.
6. + exchanger isoform NHE-1 in rabbit kidney. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F833-F840, 1992.
7. + exchangers, NHE-1 and NHE-3, of rat intestines. J. Clin. Invest. 93: 106-113, 1994.
8. Chomczynski, P., and N. Sacchi. Single step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal. Biochem. 162: 156-159,1987.
9. + exchanger NHE-1 possesses N- and O- linked glycosylation restricted to the first N-terminal extracellular domain. Biochemistry 33: 10463-10469, 1994.
10. Doctor, R. B., and L. J, Mandel. Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury. J. Am. Soc. Nephrol. 1: 959-969, 1991.
11. Feinberg, A. P., and B. Vogelstein. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 162: 156-159, 1987.
12. Grinstein, S., and A. Rothstein. Mechanisms of regulation of the Na"/H+ exchanger. J. Membr. Biol. 90: 1-12, 1986.
13. Haggerty, J. G., N. Agarwal, R. F. Reilly, E. A. Adelberg, and C. W. Slayman. Pharmacologically different Na/H antiporters on the apical and basolateral surfaces of cultured porcine kidney cells (LLC-PKi). Proc. Natl. Acad. Sei. USA 85: 6797-6801,1988.
14. + antiport activity in rat renal cortex. Kidney Int. 37: 707-716, 1990.
15. Horowitz, B., C. B. Hensley, M. Quintero, K. K. Azuma, D. S. Putnam, and A. A. McDonough. Differential regulation of Na,K-ATPase α1, α2 and βsubunit mRNA levels by thyroid hormone. J. Biol. Chem. 265: 14308-14314, 1990.
16. Igarashi, P., R. F. Reilly, F. Hildebrandt, D. Biemesderfer, N. A. Reboucas, C. W. Slayman, and P. S. Aronson. Molecular biology of renal Na-H exchangers. Kidney Int. 40: S84-S89, 1991.
17. Kinsella, J., and B. Sacktor. Thyroid hormones increase Na-H exchange activity in renal brush border membranes. Proc. Natl. Acad. Sei. USA 82: 3606-3610, 1985.
18. Lescale-Matys, L., C. B. Hensley, D. Putnam, and A. McDonough. Low K+ stimulates a specific increase in beta mRNA driving the synthesis and accumulation of Na,K-ATPase. J. Biol. Chem. 265: 17935-17940, 1990.
19. + exchangers stably expressed in a fibroblast cell line. J. Biol. Chem. 268: 25527-25535, 1993.
20. +-ATPase α- and β-subunit mRNA levels in kidney. Am. J. Physiol. 254 (Cell Physiol. 23): C323-C329, 1988.
21. Michael, U. F., J. Kelley, and C. A. Vaamonde. Impaired renal bicarbonate reabsorption in the hypothyroid rat. Am. J. Physiol. 236 (Renal Fluid Electrolyte Physiol. 5): F536-F540, 1979.
22. Mrkic, B., C.-M. Tse, J. Forgo, C. Helmle-Kolb, M. Donowitz, and H. Murer. Identification of PTH-responsive Na/H exchanger isoforms in a rabbit proximal tubule cell line (RKPC-2). Pfluegers Arch. 424: 377-384, 1993.
23. Orlowski, J. Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger. J. Biol. Chem. 268: 1636916377,1993.
24. Orlowski, J., R. A. Kandasamy, and G. E. Shull. Molecular cloning of putative members of the Na/H exchanger gene family. J. Biol. Chem. 267: 9331-9339, 1992.
25. Orlowski, J., and J. B. Lingrel. Tissue specific and developmental regulation of rat Na,K-ATPase catalytic a isoform and β subunit mRNAs. J. Biol. Chem. 263: 10436-10442, 1988.
26. Pizzonia, J. H., M. Exner, D. Biemesderfer, A. K. Abu-Alfa, M. S. Wu, P. Igarashi, and P. S. Aronson. Immunochemical characterization of the Na/H exchanger isoform NHE4 in rat kidney (Abstract). J. Am. Soc. Nephrol. 5: 297, 1994.
27. 4 antiporter. Cell 56: 271-280,1989.
28. Shyjan, A. W., and R. Levenson. Antisera specific for the al, α2, α3, and β subunits of the Na,K-ATPase: differential expression of a and β subunits in rat tissue membranes. Biochemistry 28:4531-4535, 1988.
29. + exchange in renal proximal tubule cells. J. Biol. Chem. 269: 15613-15618,1994.
30. Soleimani, M., G. Singh, G. L. Bizal, S. R. Gullans, and J. A. McAteer. Na/H exchanger isoforms NHE-2 and NHE-1 in inner medullary collecting duct cells. J. Biol. Chem. 269: 27973-27978, 1994.
31. Tarn, J. P. Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. Proc. Natl. Acad. Sei. USA 85: 5409-5413, 1988.
32. Tse, C.-M., S. R. Brant, M. S. Walker, J. Pouyssegur, and M. Donowitz. Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific NaVH' exhanger isoform (NHE-3). J. Biol. Chem. 267: 9340-9346, 1992.
33. + exchanger gene family. J. Membr. Biol. 135: 93-108, 1993.
34. Tse, C.-M., S. A. Levine, C. H. C. Yun, M. H. Montrose, P. J. Little, J. Pouyssegur, and M. Donowitz. Cloning and expression of a rabbit cDNA encoding a serum activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2). J. Biol. Chem. 268: 11917-11924,1993.
35. Wang, Z., J. Orlowski, and G. E. Shull. Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exhanger. J. Biol. Chem. 268: 11925-11928, 1993.
36. Yu, F. H., G. E. Shull, and J. Orlowski. Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells. J. Biol. Chem. 268: 25536-25541, 1993.
37. + exchanger isoform. J. Biol. Chem. 268: 206-211,1993.
38. Yusufi, A. N. K., N. Murayama, M. J. Keller, and T. P. Dousa. Modulatory effect of thyroid hormones on uptake of phosphate and other solutes across luminal brush border membrane of kidney cortex. Endocrinology 116: 2438-2449, 1985.