Cross-chest median nerve transfer: A new model for the evaluation of nerve regeneration across a 40 mm gap in the rat

Journal of Neuroscience Methods

Volumn 156, Issue 1-2, 2006, Pages 166-172

  Sinis, Nektarios ^a   Schaller, Hans Eberhard ^a   Becker, Stephan Thomas ^b   Lanaras, Tatjana ^a   Schulte Eversum, Caterina ^c   Müller, Hans Werner ^c   Vonthein, Reinhard ^a   Rösner, Harald ^d   Haerle, Max ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Axon counts; Cross chest transfer; Median nerve; Nerve regeneration; Ulnar nerve

Indexed keywords

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; HISTOLOGY; MEDIAN NERVE; NERVE FIBER REGENERATION; NERVE GRAFT; NERVE REGENERATION; NERVE SUTURE; NERVE TRANSPLANTATION; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; ULNAR NERVE;

ANIMALS; AXONS; BODY WEIGHT; CELL COUNT; MEDIAN NERVE; NERVE REGENERATION; RATS; RATS, INBRED LEW; TRANSPLANTATION, AUTOLOGOUS; ULNAR NERVE;

EID: 33747449009     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2006.02.022     Document Type: Article

References (22)

1. Angelov D.N., Neiss W.F., Streppel M., Andermahr J., Mader K., and Stennert E. Nimodipine accelerates axonal sprouting after surgical repair of rat facial nerve. J Neurosci 16 (1996) 1041-1048
2. Battiston B., Geuna S., Ferrero M., and Tos P. Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair. Microsurgery 25 (2005) 258-267
3. Bertelli J.A., dos Santos A.R., Taleb M., Calixto J.B., Mira J.C., and Ghizoni M.F. Long interpositional nerve graft consistently induces incomplete motor and sensory recovery in the rat. An experimental model to test nerve repair. J Neurosci Methods 15 (2004) 75-80
4. Bertelli J.A., Guizoni M.F., Dos Santos A.R., Calixto J.B., and Duarte H.E. Cross-chest radial nerve transfer in brachial plexus injuries. Experimental and anatomical basis. Chir Main 18 (1999) 122-131
5. Bertelli J.A., and Mira J.C. The grasping test: a simple behavioral method for objective quantitative assessment of peripheral nerve regeneration in the rat. J Neurosci Methods 58 (1995) 151-155
6. Bertelli J.A., Taleb M., Saadi A., Mira J.C., and Pecot-Dechavassine M. The rat brachial plexus and its terminal branches: an experimental model for the study of peripheral nerve regeneration. Microsurgery 16 (1995) 77-85
7. Bontioti E., Kanje M., Lundborg G., and Dahlin L.B. End-to-side nerve repair in the upper extremity of rat. J Peripher Nerv Syst. 10 (2005) 58-68
8. Buti M., Verdu E., Labrador R.O., Vilches J.J., Fores J., and Navarro X. Influence of physical parameters of nerve chambers on peripheral nerve regeneration and reinnervation. Exp Neurol 137 (1996) 26-33
9. Guntinas-Lichius O., Irintchev A., Streppel M., Lenzen M., Grosheva M., Wewetzer K., et al. Factors limiting motor recovery after facial nerve transection in the rat: combined structural and functional analyses. Eur J Neurosci 21 (2005) 391-402
10. Heath C.A., and Rutkowski G.E. The development of bioartificial nerve grafts for peripheral-nerve regeneration. Trends Biotechnol 16 (1998) 163-168
11. Jenq C.B., Hulsebosch C.E., Coggeshall R.E., and Perez-Polo J.R. The effects of nerve growth factor and its antibodies on axonal numbers in the medial gastrocnemius nerve of the rat. Brain Res. 7 (1984) 9-14
12. Kannan R.Y., Salacinski H.J., Butler P.E., and Seifalian A.M. Artificial nerve conduits in peripheral-nerve repair. Biotechnol Appl Biochem 41 (2005) 193-200
13. Kerns J.M., Malushte T.S., Nagel T., Shott S., Safanda J., and Gonzalez M. Repair of partial lesions with nerve grafting methods in the rat tibial nerve. J Reconstr Microsurg 21 (2005) 257-266
14. Manley M.T., and Darby T. Repetitive mechanical stress and denervation in plantar ulcer pathogenesis in rats. Arch Phys Med Rehab 61 (1980) 171-177
15. Papalia I., Tos P., Stagno d'Alcontres F., Battiston B., and Geuna S. On the use of the grasping test in the rat median nerve model: a re-appraisal of its efficacy for quantitative assessment of motor function recovery. J Neurosci Methods 127 (2003) 43-47
16. Robinson G.A., and Madison R.D. Manipulations of the mouse femoral nerve influence the accuracy of pathway reinnervation by motor neurons. Exp Neurol 192 (2005) 39-45
17. Sinis N., Schaller H.E., Schulte-Eversum C., Schlosshauer B., Doser M., Dietz K., et al. Nerve regeneration across a 2 cm gap in the rat median nerve using a resorbable nerve conduit filled with Schwann cells. J Neurosurg 103 (2005) 1067-1076
18. Sporel-Ozakat R.E., Edwards P.M., Hepgul K.T., Savas A., and Gispen W.H. A simple method for reducing autotomy in rats after peripheral nerve lesions. J Neurosci Methods 36 (1991) 263-265
19. Tos P., Calcagni M., Gigo-Benato D., Boux E., Geuna S., and Battiston B. Use of muscle-vein-combined Y-chambers for repair of multiple nerve lesions: experimental results. Microsurgery 24 (2004) 459-464
20. Varejao A.S., Cabrita A.M., Meek M.F., Bulas-Cruz J., Melo-Pinto P., Raimondo S., et al. Functional morphological assessment of a standardized rat sciatic nerve crush injury with a non-serrated clamp. J Neurotraum 21 (2004) 1652-1670
21. Varejao A.S., Meek M.F., Ferreira A.J., Patricio J.A., and Cabrita A.M. Functional evaluation of peripheral nerve regeneration in the rat: walking track analysis. J Neurosci Methods 108 (2001) 1-9
22. Worthington C.R. Structural parameters of nerve myelin. Proc Natl Acad Sci USA 63 (1969) 604-611