Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation

British Journal of Haematology

Volumn 134, Issue 6, 2006, Pages 640-644

  Sanmun, Duangmanee ^a   Garwicz, Daniel ^a   Edvard Smith, C I ^b   Palmblad, Jan ^b   Fadeel, Bengt ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Apoptosis; Chemokines; Growth factors; Kinases; Neutropenia

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; IMMUNOGLOBULIN; JANUS KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; STROMAL CELL DERIVED FACTOR 1;

ADULT; APOPTOSIS; ARTICLE; CASE REPORT; COMBINED IMMUNODEFICIENCY; FEMALE; GENE MUTATION; HUMAN; HYPOGAMMAGLOBULINEMIA; INFECTION; MYELOKATHEXIS; NEUTROPENIA; NEUTROPHIL; PRIORITY JOURNAL; VERRUCA VULGARIS; WHIM SYNDROME;

ADULT; AGAMMAGLOBULINEMIA; APOPTOSIS; CASE-CONTROL STUDIES; CELL CULTURE TECHNIQUES; CHEMOKINES, CXC; FEMALE; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFECTION; MUTATION; NEUTROPHILS; RECEPTORS, CXCR4; SYNDROME; WARTS;

EID: 33747445532     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2006.06240.x     Document Type: Article

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