Molecular vibrational analysis and MAS-NMR spectroscopy study of epilepsy drugs encapsulated in TiO2-sol-gel reservoirs

Journal of Biomedical Materials Research - Part A

Volumn 78, Issue 3, 2006, Pages 441-448

  Lopez, T ^a,b   Navarrete, J ^c   Conde, R ^c   Ascencio, J A ^c   Manjarrez, J ^b   Gonzalez, R D ^d  

^a DEPARTAMENTO DE QUÍMICA   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c INSTITUTO MEXICANO DEL PETRÓLEO   (Mexico)

^d Tulane University   (United States)

Author keywords

Drug delivering; Epilepsy; Molecular vibrational analysis; Nanostructured reservoir; Quantum mechanics calculations; Sol gel; TiO2

Indexed keywords

DRUG DELIVERING; ELECTROSTATIC POTENTIAL DISTRIBUTION; EPILEPSY; NANOSTRUCTURED RESERVOIR; QUANTUM MECHANICS CALCULATIONS;

CRYSTAL STRUCTURE; ENCAPSULATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GELATION; HYDROGEN BONDS; MOLECULAR VIBRATIONS; NANOSTRUCTURED MATERIALS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POROSITY; QUANTUM THEORY; SOL-GELS; TITANIUM DIOXIDE;

DRUG PRODUCTS;

ANTICONVULSIVE AGENT; PHENYTOIN; TITANIUM DIOXIDE; VALPROIC ACID;

ANTICONVULSANT THERAPY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DIPOLE; DRUG DELIVERY SYSTEM; EPILEPSY; FOURIER TRANSFORMATION; GEL; HUMAN; HYDROGEN BOND; INFRARED RADIATION; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM MECHANICS; SOLID; SYNTHESIS; VIBRATION;

ANTICONVULSANTS; CAPSULES; DRUG DELIVERY SYSTEMS; GELS; MAGNETIC RESONANCE SPECTROSCOPY; TITANIUM;

EID: 33747441117     PISSN: 00219304     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30842     Document Type: Article

References (22)

1. Walczak T. Neocortical temporal lobe epilepsy: Characterizing the syndrome. Epilepsia 1995;36:633-635.
2. O'Connor MJ, Sperling M, Liporace J, Sirven J, Freese A. Mutiple subpial transection: An adjunct to resective surgery for epilepsy in eloquent cortex. Epilepsia 1999;40:76-76.
3. Williamson P, Engel J, Munari C. Anatomic classification of localization-related epilepsies. In: Engel J, editor. Epilepsy: A Comprehensive Textbook, Vol. 3. New York: Lippincott-Raven Press; 1998. pp 2405-2416.
4. Ebersole JS, Wade PD. Spike voltage topography identifies two types of frontotemporal epileptic foci. Neurology 1991;41:1425-1433.
5. Henry T, Sutherling W, Engel J. Interictal cerebral metabolism in partial epilepsies of neocortical origin. Epilepsy Res 1991;10: 174-182.
6. Stefan H, Feichtinger M, Pauli E. Magnetic resonance spectroscopy and histopathological findings in temporal lobe epilepsy. Epilepsia 2001;42:41-46.
7. Hitten P, Druchrow R, Lanerolle NC, Spencer S. Epilepsy treatment. Epilepsia 2001;42:725-730.
8. Perucca E. Pharmacological principles as a basis for polytherapy. Acta Neurol Scand 1995;162:31-34.
9. Schmidt D. Rational polytherapy. Baillieres Clin Neurol 1996; 5:757-763.
10. Engel JJ, Van Ness P, Rasmussen T, Ojemann L. Outcome with respect to epileptic seizures. In: Engel J Jr, editor. Surgical Treatment of the Epilepsies, 2nd ed. New York: Raven Press; 1993. pp 609-621.
11. Benbadis SR, So NK, Antar MA, Barnett GH, Morris HH. The value of PET scan (and MRI and Wada test) in patients with bitemporal epileptiform abnormalities. Arch Neurol 1995;52: 1062-1068.
12. Bohnen NI, O'Brien TJ, Mullan BP, So EL. Cerebellar changes in partial seizures: Clinical correlations of quantitative SPECT and MRI analysis. Epilepsia 1998;39:640-650.
13. Cendes F, Caramanos Z, Andermann F, Dubeau F, Arnold DL. Proton magnetic resonance spectroscopic imaging and magnetic resonance imaging volumetry in the lateralization of temporal lobe epilepsy: A series of 100 patients. Ann Neurol 1997;42:737-746.
14. Koepp MJ, Richardson MP, Labbe C, Brooks DJ, Cunningham VJ, Ashburner J, Van PW, Revesz T, Duncan JS. 11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy. Neurology 1997;49:764-773.
15. Ferro-Flores G, Ramírez FD, Tendilla JI, Pimentel-González G, Murphy CA, Meléndez-Alafort L, Ascencio JA, Croft BY. Preparation and pharmacokinetics of samarium (III)-153-labeled DTPA-bis-biotin. Characterization and theoretical studies of the samarium(III)-152 conjugate. Bioconjug Chem 1999;10:726-734.
16. 2+ sensor. Afinidad 2000;487:180-184.
17. Lapinski L, Nowak MJ, Kwiatkowski JS, Leszczynski J. Photo-tautomeric reaction, tautomerism, and infrared spectra of 6-thiopurine. Experimental matrix isolation and quantum-mechanical (conventional ab initio and density-functional theory) studies. J Phys Chem A 1999;103:280-288.
18. Ascencio JA, Rodriguez-Lugo V, Angeles C, Santamara T, Castano VM. Theoretical analysis of hydroxylapatite and its main precursors by quantum mechanics and HREM image simulation. Comp Mat Sci 2002;25:413-426.
19. 2. San Diego: Accelrys; 1999.
20. 2 sol-gel derived catalysts. J Sol-Gel Sci Technol 2001;22: 99-107.
21. Podbielska H, Ulatowska-Jarza A, Holowacz I. Sol-gel applicators for medical light therapy. Phys Med 2004;20:37-39.
22. 2 sol-gels. Langmuir 1996;12:4385-4390.