Elevated vitamin A intake and serum retinol in preadolescent children with cystic fibrosis

American Journal of Clinical Nutrition

Volumn 84, Issue 1, 2006, Pages 174-182

  Graham Maar, Rose C ^a   Schall, Joan I ^a   Stettler, Nicolas ^b   Zemel, Babette S ^a   Stallings, Virginia A ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Children; Cystic fibrosis; Hypervitaminosis A; National Health and Nutrition Examination Survey; NHANES; Retinol; Vitamin A

Indexed keywords

ACETIC ACID; BETA CAROTENE; PALMITIC ACID; RETINOL; VITAMIN;

ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CYSTIC FIBROSIS; DIETARY INTAKE; FEMALE; HUMAN; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; PANCREAS INSUFFICIENCY; SCHOOL CHILD; VITAMIN INTAKE; VITAMIN SUPPLEMENTATION; BLOOD; CHILD; CHILD NUTRITION; CLINICAL TRIAL; CROSS-SECTIONAL STUDY; DIET SUPPLEMENTATION; HEALTH CARE POLICY; MULTICENTER STUDY; NUTRITION; PANCREAS EXOCRINE INSUFFICIENCY; RETINOL DEFICIENCY; UNITED STATES;

CHILD; CHILD NUTRITION PHYSIOLOGY; CROSS-SECTIONAL STUDIES; CYSTIC FIBROSIS; DIETARY SUPPLEMENTS; EXOCRINE PANCREATIC INSUFFICIENCY; FEMALE; HUMANS; MALE; NUTRITION POLICY; NUTRITION SURVEYS; UNITED STATES; VITAMIN A; VITAMIN A DEFICIENCY; VITAMINS;

EID: 33747428718     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/84.1.174     Document Type: Article

References (38)

1. Cystic Fibrosis Foundation. Patient registry 2004. Annual report. Bethesda, MD: Cystic Fibrosis Foundation, 2005.
2. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, DC: National Academy Press, 2001:82-161.
3. Bendich A, Langseth L. Safety of vitamin A. Am J Clin Nutr 1989;49:358-71.
4. Penniston KL, Tanumihardjo SA. The acute and chronic toxic effects of vitamin A. Am J Clin Nutr 2006;83:191-201.
5. Lancellotti L, D'Orazio C, Mastella G, Mazzi G, Lippi U. Deficiency of vitamins E and A in cystic fibrosis is independent of pancreatic function and current enzyme and vitamin supplementation. Eur J Pediatr 1996;155:281-5.
6. Underwood BA, Denning CR. Blood and liver concentrations of vitamins A and E in children with cystic fibrosis of the pancreas. Pediatr Res 1972;6:26-31.
7. Congden P, Bruce G, Rothburn M, et al. Vitamin status in treated patients with cystic fibrosis. Arch Dis Child 1981;56:708-14.
8. O'Donnell M, Talbot J. Vitamin A deficiency in treated cystic fibrosis: case report. Br J Ophthalmol 1987;71:787-90.
9. Rasmussen M, Michalsen H, Lie SO, Nilsson A, Petersen LB, Norum KR. Intestinal retinol esterification and serum retinol in children with cystic fibrosis. J Pediatr Gastroenterol Nutr 1986;5:397-403.
10. Rayner RJ, Tyrrell JC, Hiller EJ, et al. Night blindness and conjunctival xerosis caused by vitamin A deficiency in patients with cystic fibrosis. Arch Dis Child 1989;64:1151-6.
11. Sokol RJ, Reardon MC, Accurso FJ, et al. Fat-soluble-vitamin status during the first year of life in infants with cystic fibrosis identified by screening of newborns. Am J Clin Nutr 1989;50:1064-71.
12. Feranchak AP, Sontag MK, Wagener JS, Hammond KB, Accurso FJ, Sokol RJ. Prospective, long-term study of fat-soluble vitamin status in children with cystic fibrosis identified by newborn screen. J Pediatr 1999;135:601-10.
13. Borowitz D, Baker R, Stallings V. Consensus report on nutrition for pediatric patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 2002;35:246-59.
14. Peters SA, Rolles CJ. Vitamin therapy in cystic fibrosis - a review and rationale. J Clin Pharm Ther 1993;18:33-8.
15. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Washington, DC: National Academy Press, 2002:107-264.
16. Schoeller DA, Ravussin E, Schutz Y, Acheson KJ, Baertschi P, Jequier E. Energy expenditure by doubly labeled water: validation in humans and proposed calculation. Am J Physiol 1986;250:R823-30.
17. Weir JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949;109:1-9.
18. Tomezsko JL, Stallings VA, Kawchak DA, Goin JE, Diamond G, Scanlin TF. Energy expenditure and genotype of children with cystic fibrosis. Pediatr Res 1994;35:451-60.
19. Lohman T, Roche A, Martorell R. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics Books, 1988.
20. CDC. 2000 CDC growth charts. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Health Statistics, 2000.
21. Gardner R. Report of snowbird workshop on standardization of spirometry. Am Rev Resp Dis 1979;119:831-8.
22. Morris A, Kanner R, Crapo R, Gardner R. Clinical pulmonary function testing: a manual of uniform laboratory procedures. 2nd ed. Salt Lake City, UT: Intermountain Thoracic Society, 1984.
23. Zapletal A. Lung function in children and adolescents - methods, reference values. In: Herzog H, ed. Progress in Respiration Research. Pratteln, Switzerland: Offsetdruck, 1987.
24. Binkley N, Krueger D. Hypervitaminosis A and bone. Nutr Rev 2000;58:138-44.
25. Crandall C. Vitamin A intake and osteoporosis: a clinical review. J Womens Health 2004;13:939-53.
26. Feskanich D, Singh V, Willett W, Colditz G. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54.
27. Genaro Pde S, Martini L. Vitamin A supplementation and risk of skeletal fracture. Nutr Rev 2004;62:65-7.
28. Lim L, Harnack L, Lazovich D, Folsom A. Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women's Health Study. Osteoporos Int 2004;15:552-9.
29. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8.
30. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.
31. Opotowsky A, Bilezikian J. Serum vitamin A concentration and the risk of hip fracture among women 50 to 74 years old in the United States: a prospective analysis of the NHANES I follow-up study. Am J Med 2004;117:169-74.
32. Geubel A, De Galocsy C, Alves N, Rahier J, Dive C. Liver damage caused by therapeutic vitamin A administration: estimate of dose-related toxicity in 41 cases. Gastroenterology 1991;100:1701-9.
33. Eid N, Shoemaker L, Samiec T. Vitamin A in cystic fibrosis: case report and review of the literature. J Pediatr Gastroenterol Nutr 1990;10:265-9.
34. Lindblad A, Diczfalusy U, Hultcrantz R, Thorell A, Strandvik B. Vitamin A concentration in the liver decreases with age in patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 1997;24:264-70.
35. Myhre A, Carlsen M, Bohn S, Wold H, Laake P, Blomhoff R. Water-miscible, emulsified, and solid forms of retinol supplements are more toxic than oil-based preparations. Am J Clin Nutr 2003;78:1152-9.
36. Ahmed F, Ellis J, Murphy J, Wootton S, Jackson AA. Excessive faecal losses of vitamin A (retinol) in cystic fibrosis. Arch Dis Child 1990;65:589-93.
37. Biesalski HK, Nohr D. New aspects in vitamin a metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epithelia. J Nutr 2004;134(suppl):3453S-57S.
38. Schmitz HH, Poor CL, Wellman RB, Erdman JW Jr. Concentrations of selected carotenoids and vitamin A in human liver, kidney and lung tissue. J Nutr 1991;121:1613-21.