Neuromyelitis optica and anti-aquaporin-4 antibodies: Widening the clinical phenotype

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 77, Issue 9, 2006, Pages 1001-1002

  Giovannoni, G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; AQUAPORIN 3; AQUAPORIN 4; AQUAPORIN 5; AQUAPORIN 8; AUTOANTIBODY; AZATHIOPRINE; CORTICOSTEROID; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; AQP4 PROTEIN, HUMAN;

CEREBROSPINAL FLUID; EDITORIAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MYELOOPTIC NEUROPATHY; NONHUMAN; PHENOTYPE; PLEOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; BRAIN; IMMUNOLOGY; MULTIPLE SCLEROSIS; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY;

AQUAPORIN 4; AUTOANTIBODIES; BRAIN; HUMANS; MAGNETIC RESONANCE IMAGING; MULTIPLE SCLEROSIS; NEUROMYELITIS OPTICA; PHENOTYPE;

EID: 33747425555     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2006.090944     Document Type: Editorial

References (18)

1. Weinshenker BG. Neuromyelitis optica: what it is and what it might be. Lancet 2003;361:889-90.
2. Weinshenker B. Western vs optic-spinal MS: two diseases, one treatment? Neurology 2005;64:594-5.
3. Lucchinetti CF, Mandler RN, McGavern D, et al. A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain 2002;125:1450-61.
4. Lennon VA, Wingerchuk DM, Kryzer TJ, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004;364:2106-12.
5. Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005;202:473-7.
6. Bedford JJ, Leader JP, Walker RJ. Aquaporin expression in normal human kidney and in renal disease. J Am Soc Nephrol 2003;14:2581-7.
7. Lehmann GL, Gradilone SA, Marinelli RA. Aquaporin water channels in central nervous system. Curr Neurovasc Res 2004;1:293-303.
8. Wingerchuk DM, Hogancamp WF, O'Brien PC, et al. The clinical course of neuromyelitis optica (Devic's syndrome). Neurology 1999;53:1107-14.
9. Poppe AY, Lapierre Y, Melancon D, et al. Neuromyelitis optica with hypothalamic involvement. Mult Scler 2005;11:617-21.
10. Nakamura M, Endo M, Murakami K, et al. An autopsied case of neuromyelitis optica with a large cavitary cerebral lesion. Mult Scler 2005;11:735-8.
11. Misu T, Fujihara K, Nakashima I, et al. Intractable hiccup and nausea with periaqueductal lesions in neuromyelitis optica. Neurology 2005;65:1479-82.
12. Pittock SJ, Weinshenker B, Lucchinetti CF, et al. MRI brain lesions characteristic of neuromyelitis optica (NMO) colocalize with sites of high aquoporin protein concentrations. Neurology 2006:S22.004.
13. Nakashima I, Fujihara K, Miyazawa I, et al. Clinical and MRI features of Japanese MS patients with NMO-IgG. J Neurol Neurosurg Psychiatry 2006;77:1073-5.
14. Pittock SJ, Lennon VA, Krecke K, et al. Brain abnormalities in neuromyelitis optica. Arch Neurol 2006;63:390-6.
15. Chan KH, Tsang KL, Fong GC, et al. Idiopathic severe recurrent transverse myelitis: a restricted variant of neuromyelitis optica. Clin Neurol Neurosurg 2005;107:132-5.
16. Kidd D, Burton B, Plant GT, et al. Chronic relapsing inflammatory optic neuropathy (CRION). Brain 2003;126(Pt 2):276-84.
17. Wingerchuk DM, Weinshenker BG. Neuromyelitis Optica. Curr Treat Options Neurol 2005;7:173-82.
18. Keegan M, Pineda AA, McClelland RL, et al. Plasma exchange for severe attacks of CNS demyelination: predictors of response. Neurology 2002;58:143-6.