"In vivo" local transfection of a cis element decoy mimicking an estrogen receptor alpha gene promoter region induces apoptosis of osteoclasts following application of orthodontic forces to rat teeth

Apoptosis

Volumn 11, Issue 9, 2006, Pages 1653-1656

  Penolazzi, Letizia ^a   Magri, Eros ^a   Lambertini, Elisabetta ^a   Bianchini, Ercolina ^a   Piva, Roberta ^a   Gambari, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; EDETIC ACID; ESTROGEN RECEPTOR ALPHA; FAS ANTIGEN; FAS RECEPTOR; OLIGONUCLEOTIDE; OLIGONUCLEOTIDE RA4 3'; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALVEOLAR BONE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INDUCTION; LETTER; MALE; NICK END LABELING; NONHUMAN; ORTHODONTICS; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; PRIORITY JOURNAL; PROMOTER REGION; RAT; RHEUMATOID ARTHRITIS; TOOTH DEVELOPMENT; TRANSCRIPTION FACTOR DECOY APPROACH;

ANIMALS; APOPTOSIS; ESTROGEN RECEPTOR ALPHA; MOLECULAR MIMICRY; ORTHODONTIC SPACE CLOSURE; OSTEOCLASTS; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; RATS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; TOOTH; TRANSFECTION;

EID: 33747412562     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-8763-2     Document Type: Letter

References (5)

1. Piva R, Penolazzi L, Lambertini E, Giordano S, Gambari R (2005) Induction of apoptosis of human primary osteoclasts treated with a transcription factor decoy mimicking a promoter region of estrogen receptor alpha. Apoptosis 10:1079-1094
2. Kobayashi Y, Hashimoto F, Miyamoto H, Kanaoka K, Miyazaki-Kawashita Y, Nakashima T et al (2000) Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. J Bone Miner Res 15:1924-1934
3. Adachi H, Igarashi K, Mitani H, Shinoda H (1994) Effects of topical administration of bisphosphonate (risedronate) on orthodontic tooth movements in rats. J Dent Res 73:1478-1484
4. Roodman GD (1996) Advances in bone biology: The osteoclasts. Endocr Rev 17:308-332
5. King GJ, Keeling SD, Wronski TJ (1991) Histomorphometric study of alveolar bone turnover in orthodontic tooth movement. Bone 12:401-409