Stereocontrolled synthesis of tricyclic fused oxazolidinone as antibacterial agent

Journal of Heterocyclic Chemistry

Volumn 43, Issue 4, 2006, Pages 1071-1075

  Cui, Yingjie ^a   Dang, Yaxian ^a   Yang, Yushe ^a   Ji, Ruyun ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LINEZOLID; OXAZOLIDINONE DERIVATIVE;

ACYLATION; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; CROSS RESISTANCE; CYCLIZATION; GRAM POSITIVE BACTERIUM; MULTIDRUG RESISTANCE; RIBOSOME SUBUNIT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 33747407348     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570430438     Document Type: Article

References (14)

1. S. Brickner, D. Hutchinson, M. Barbachyn, P. Manninen, D. Ulanowicz, S. Garmon, K. Grega, S. Hedges, D. Toops, C. Ford and G. Zurenko, J. Med. Chem. 39, 673 (1996).
2. D. J. Diekema and R. N. Jones, Drugs, 59, 7 (2000).
3. Scrip, 2484, 24 (1999).
4. B. Bozdogan and P. C. Appelbaum, Int. J. Antimicrob. Agents, 23, 113 (2004).
5. S. M. Swaney, H. Aoki and M. C. Ganoza, Antimicrob. Agents Chemother., 41, 2132 (1997).
6. D. Clemett and A. Markham, Drugs, 59, 815 (2000).
7. N. Woodford, Exp. Opin. Invest. Drugs, 12, 117 (2003).
8. B. Ryan, H.T. Ho, P. Wu, Exp. Opin. Invest. Drugs, 9, 2945 (2000).
9. S. J. Brickner, US Patent 5,231,188 (1993); Chem. Abstr., 120, 1833005u (1994).
10. S. J. Brickner, US Patent 5,247,090 (1993); Chem. Abstr., 120, 2103760w (1994).
11. D. M. Gleave, S. J. Brickner, P. R. Manninen, D.A. Allwine, K. D. Lovasz, D. C. Rohrer, J. A. Tucker, G. E. Zurenko and C. W. Ford, Bioorg. Med. Chem. Lett., 8, 1231 (1998).
12. D. M. Gleave, S. J. Brickner, J. Org. Chem., 61, 6470 (1996).
13. HPLC analysis was performed using the following conditions: Chiralcel OD (Daicel) (0.46cm × 25cm), mobile phase: n-hexane/isopropanol = 9:1, flow rate 0.4 mL/min, temperature: 25 °C.
14. National Committee for Clinical Laboratory Standards. NCCLS Document M7-A3 (ISBN 1-56238-209-8); NCCLs: 771 Lancaster Ave., Villanova, PA 19085, 1993.