Aromatization and ring cyclization: A reasonable understanding on the ring cyclization mechanism of 3-amino-6-hydrazino-1,2,4-triazin-5(2H)-one reacted with one-carbon fragment reagents or nitrous acid

Journal of Heterocyclic Chemistry

Volumn 43, Issue 4, 2006, Pages 889-895

  Hwang, Long Chih ^a   Tu, Chun Hsien ^b   Wang, Jung Hui ^c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b Department of Psychiatry   (Taiwan)

^c KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIAZINE DERIVATIVE; 1,2,4 TRIAZOLO[3,4 F][1,2,4]TRIAZIN 8(7H) ONE; 2 N (2 AMINO 1 BENZYL 4 OXO 1,2,4 TRIAZIN 5 YL)SEMICARBAZIDE; 3 AMINO 2 BENZYL 6 (2 ACETYLHYDRAZINO) 1,2,4 TRIAZIN 5(2H) ONE; 3 AMINO 2 BENZYL 6 (2 FORMYLHYDRAZINO) 1,2,4 TRIAZIN 5(2H) ONE; 3 AMINO 2 BENZYL 6 HYDRAZINO 1,2,4 TRIAZIN 5(2H) ONE; 3 AMINO 6 AZIDO 2 BENZYL 1,2,4 TRIAZIN 5(2H) ONE; 3 AMINO 6 HYDRAZINO 1,2,4 TRIAZIN 5(2H) ONE; 3 AMINO 6 HYDRAZINO 2 [(2 HYDROXYETHOXY)METHYL] 1,2,4 TRIAZIN 5(2H) ONE; 6 AMINO 1,2,3,4 TETRAZOLO[5,1 F][1,2,4]TRIAZIN 8(7H) ONE; 6 AMINO 3 METHYL 1,2,4 TRIAZOLO[3,4 F][1,2,4]TRIAZIN 8(7H) ONE; CARBON; HETEROCYCLIC COMPOUND; NITROUS ACID; REAGENT; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

EID: 33747397958     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570430412     Document Type: Article

References (13)

1. H. Neunhoeffer and P. F. Wiley, in Chemistry of 1,2,3-Triazines and 1,2,4-Triazines, Tetrazines and Pentazines, A. Weissberger and E. C. Taylor, eds, John Wiley and Sons, New York, NY, 1978, pp 1001-1004.
2. E. S. H. EL Ashry, N. Rashed, M. Taha and E. Ramadan, Adv. Heterocycl. Chem., 59, 41 (1994).
3. E. Pomarnacka, Acta Pol Pharm., 55, 481 (1998).
4. R. M. Abdel-Rahman, Pharmazie, 56, 275 (2001).
5. Z. El-Gendy, J. M. Morsy, H. A. Allimony, W. R. Ali and R. M. Abdel-Rahman, Pharmazie, 56, 376 (2001).
6. H. G. O. Becker, D. Beyer, G. Israel, R. Muller, W. Riediger and H. J. Timpe, J. Prakt. Chem., 312, 669 (1970).
7. C. A. Lovelette, J. Heterocyclic Chem., 16, 555 (1979).
8. J. Elguero, A. R. Katritzky and O. V. Denisko, Adv. Heterocycl. Chem., 76, 1 (2000).
9. L. C. Hwang, R. R. Wu, S. Y. Jane and G. H. Lee, Analytical Sciences, 19, x73-x74 (2003).
10. L. C. Hwang, J. H. Wang, C. C. Tzeng, G. H. Lee and S. M. Peng, Analytical Sciences, 18, 723 (2002).
11. L. C. Hwang, C. H. Tu, J. H. Wang, G. H. Lee and Y. Wang, Analytical Sciences, 18, 853 (2002).
12. L. C. Hwang, R. R. Wu and C. H. Tu, J. Heterocyclic Chem., 42, 851 (2005).
13. L. C. Hwang, D. C. Wei, M. C. Cheng, Y. Wang and C. C. Tzeng, Nucleosides Nucleotides, 13, 2185 (1994).