New progesterone receptor antagonists: Phosphorus-containing 11β-aryl-substituted steroids

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 19, 2006, Pages 6726-6732

  Jiang, Weiqin ^a   Allan, George ^a   Fiordeliso, James J ^a   Linton, Olivia ^a   Tannenbaum, Pamela ^a   Xu, Jun ^a   Zhu, Peifang ^a   Gunnet, Joseph ^a   Demarest, Keith ^a   Lundeen, Scott ^a   Sui, Zhihua ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Phosphorus containing steroids; Progesterone receptor antagonist

Indexed keywords

19, 24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 (4 HYDROXYPHENYL); 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 (4 TRIFLUOROMETHANSULFONYLOXYPHENYL); 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 (5,5 DIMETHYL 2 OXO 2 LAMBDA 5 [1,3,2]DIOXAPHOSPHINAN 2 YL)PHENYL]; 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 (DIPHENYLPHOSPHINOYL) PHENYL]; 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 (ETHOXYMETHYLPHOSPHINOYL)PHENYL]; 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 (HYDROXYMETHYLPHOSPHINOYL)PHENYL]; 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 [BIS(2,2,2 TRIFLUOROETHOXY)PHOSPHORYL]]PHENYL; 19,24 DINORCHOLA 4,9,20 TRIEN 3 ONE 17,23 EPOXY 11 [4 [BIS(4 CHLOROPHENYL)PHOSPHINOYL]PHENYL]; 19,24 DINORCHOLA 5(10),9(11),20 TRIEN 3 ONE 17,23 EPOXY CYCLIC 1,2 ETHANEDIYL ACETAL; 19,24 DINORCHOLA 9(11),20 DIEN 3 ONE 5,10:17,23 DIEPOXY CYCLIC 1,2 ETHANEDIYL ACETAL; 19,24 DINORCHOLA 9,20 DIEN 3 ONE 11 [4 (TETRAHYDRO 2 H PYRANOXY)PHENYL] 17,23 EPOXY 5 HYDROXY CYCLIC 1,2 ETHANEDIYL ACETAL; ANTIGESTAGEN; PHOSPHORUS; SPIRO[ESTRA 5(10),9(11) DIENE 17,2'(3'H) FURAN] 3,3' DIONE 4',5' DIHYDRO CYCLIC 3 (1,2 ETHANEDIYL ACETAL); STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ALKALINE PHOSPHATASE; ANIMALS; CATALYSIS; CELL LINE, TUMOR; COMPLEMENT C3; FEMALE; GENES, REPORTER; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; OVARIECTOMY; PALLADIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROGESTERONE; STEROIDS;

EID: 33747382085     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.05.066     Document Type: Article

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