Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands

BMC Biology

Volumn 4, Issue , 2006, Pages

  Teng, Michelle S ^a   Dekkers, Martijn P J ^b   Ng, Bee Ling ^a   Rademakers, Suzanne ^a   Jansen, Gert ^b   Fraser, Andrew G ^a   McCafferty, John ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; SOMATOSTATIN; SOMATOSTATIN 14; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR;

ANALYSIS OF VARIANCE; ARTICLE; AVOIDANCE BEHAVIOR; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GUSTATORY NERVOUS SYSTEM; HUMAN; IN VIVO STUDY; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SENSORY SYSTEM; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; NERVE CELL;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; NEURONS; RECEPTORS, CCR5; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, SOMATOSTATIN; SIGNAL TRANSDUCTION; SOMATOSTATIN;

EID: 33747368274     PISSN: 17417007     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-4-22     Document Type: Article

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