Reproductive and neurobehavioural toxicity study of Ponceau 4R administered to mice in the diet

Food and Chemical Toxicology

Volumn 44, Issue 10, 2006, Pages 1651-1658

  Tanaka, Toyohito ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Behavioural development; Food dye; Maze learning; Mice; Movement activity; New coccine; Ponceau 4R; Reproductive toxicity

Indexed keywords

FOOD DYE; SODIUM DERIVATIVE; TRISODIUM 2 HYDROXY 1 (4 SULFONATO 1 NAPHTHYLAZO) 6,8 NAPHTHALENEDISULFONATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR DISORDER; BODY WEIGHT; CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; FEMALE; LACTATION; LEARNING; LITTER SIZE; MALE; MAZE TEST; MOUSE; NEUROTOXICITY; NONHUMAN; POSTNATAL DEVELOPMENT; REPRODUCTIVE TOXICITY; SEX RATIO; TASK PERFORMANCE;

ANIMALS; AZO COMPOUNDS; BEHAVIOR, ANIMAL; BODY WEIGHT; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; LITTER SIZE; MALE; MAZE LEARNING; MICE; MOTOR ACTIVITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RANDOM ALLOCATION; REPRODUCTION;

EID: 33747364473     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.05.001     Document Type: Article

References (28)

1. Altman J., and Sudarshan K. Postnatal development of locomotion in the laboratory rat. Anim. Behav. 23 (1975) 896-920
2. Barlow S.M., Knight A.F., and Sullivan F.M. Delay in postnatal growth and development of offspring produced by maternal restraint stress during pregnancy in the rat. Teratology 18 (1978) 211-218
3. Biel W.C. Early age differences in maze performance in the albino rat. J. Genet. Psychol. 56 (1940) 439-453
4. Brantom P.G., Stevenson B.I., and Wright M.G. Long-term toxicity study of Ponceau 4R in rats using animals exposed in utero. Food Chem. Toxicol. 25 (1987) 955-962
5. Brantom P.G., Stevenson B.I., and Ingram A.J. A three-generation reproduction study of ponceau 4R in the rat. Food Chem. Toxicol. 25 (1987) 963-968
6. Fox W.M. Reflex-ontogeny and behavioural development of the mouse. Anim. Behav. 13 (1965) 234-241
7. Gaunt I.F., Farmer M., Grasso P., and Gangolli S.D. Acute (mouse and rat) and short-term (rat) toxicity studies on Ponceau 4R. Food Cosmet. Toxicol. 5 (1967) 187-194
8. International Conference on Harmonization of Technical Requirement for Registration of Pharmaceuticals for Human Use (ICH), 1993. Detection for toxicity on reproduction for medicinal products. ICH Tripartite Guideline S5A.
9. Ishimitsu S., Mishima I., Tsuji S., and Shibata T. Comparison of estimated production of coal-tar dyes in Japan and USA. Food Sanit. Res. 48 5 (1998) 33-40 (in Japanese)
10. Ito Y. Daily intakes of food additives in Japan determinations of food additives in food (1976-1994). Food Sanit. Res. 45 6 (1995) 17-68 (in Japanese)
11. Joint FAO/WHO Expert Committee on Food Additives [JECFA] 1983. Evaluation of certain food additives and contaminants. World Health Organization Technical Report Series, vol. 696, p. 20.
12. Joint FAO/WHO Expert Committee on Food Additives [JECFA]. Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) 1956-1995 (First Through Forty-fourth Meetings) (1996), International Life Sciences Institute (ILSI) Press, Washington, DC pp. P-14
13. Kitatani T., Akaike M., Takayama K., and Kobayashi T. Teratological study of cefodizime sodium in mice. Intravenous administration during period of organogenesis. J. Toxicol. Sci. 13 Suppl. I (1988) 191-214 (in Japanese)
14. Martin P., and Bateson P. Measuring Behaviour: An Introductory Guide (1990), Tokai University Press, Tokyo pp. 102-122
15. Matsumoto K., Cai B., Nakamura S., and Watanabe H. A new system for the measurement and analysis of motor activity in mice. Folia Pharmacol. Jpn. 96 (1990) 31-39 (in Japanese)
16. Matsumoto K., Cai B., Sasaki K., and Watanabe H. Methamphetamine- and apomorphine-induced change in spontaneous motor activity using a new system to detect and analyze motor activity in mice. J. Pharmacol. Method. 24 (1990) 111-119
17. Meyer O., and Hansen E.V. A study of the embryotoxicity of the food colour Ponceau 4R in rats. Toxicology 5 (1975) 201-207
18. Meyer O., and Hansen E. Behavioural and developmental effects of butylated hydroxytoluene dosed rats in utero and in lactation period. Toxicology 16 (1980) 247-258
19. Momma J., Kawamata K., Takada K., Horiuchi S., and Tobe M. A study on teratogenicity of new coccine, Food Red No. 102, in mice. Bull. Natl. Inst. Hyg. Sci. 99 (1981) 73-78
20. Nagy Z.M., and Sandmann M. Development of learning and memory of T-maze training in neonatal mice. J. Comp. Physiol. Psychol. 83 (1973) 19-26
21. Nagy Z.M., Misanin J.R., Newman J.A., Olsen P.L., and Hinderliter C.F. Ontogeny of memory in the neonatal mouse. J. Comp. Physiol. Psychol. 81 (1972) 380-393
22. Nakamura M. An out-look of food additives application in food-colorants. Food Sanit. Res. 45 1 (1995) 37-57 (in Japanese)
23. Organization for Economic Cooperation and Development (OECD), 1999. Developmental neurotoxicity study. OECD Guideline for Testing Chemicals 426.
24. 1 generation behavior in the rat. Fundam. Appl. Toxicol. 11 (1988) 440-449
25. 14C-labelled Ponceau 4R in the rat, mouse and guinea-pig. Food Chem. Toxicol. 20 (1982) 499-505
26. Tanaka T. Reproductive and neurobehavioral effects of imazalil administered to mice. Reprod. Toxicol. 9 (1995) 281-288
27. Tanaka T. The relationships between litter size, offspring weight, and behavioral development in laboratory mice Mus musculus. Mammal Study 29 (2004) 147-153
28. Tanaka T., Takahashi O., and Oishi S. Reproductive and neurobehavioural effects in three-generation toxicity study of piperonyl butoxide administered to mice. Food Chem. Toxicol. 30 (1992) 1015-1019