A rapid and simple procedure for the determination of ephedrine alkaloids in dietary supplements by gas chromatography-mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 5, 2006, Pages 1633-1641

  Marchei, Emilia ^a   Pellegrini, Manuela ^a   Pacifici, Roberta ^a   Zuccaro, Piergiorgio ^a   Pichini, Simona ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Dietary supplements; Ephedrine alkaloids; Ma Huang; Sida Cordifolia

Indexed keywords

2 PROPANOL; 3,4 METHYLENEDIOXYAMPHETAMINE DERIVATIVE; 3,4 METHYLENEDIOXYPROPYLAMPHETAMINE; ALKALOID DERIVATIVE; CHLOROFORM; EPHEDRA SINICA EXTRACT; EPHEDRINE; EPHEDRINE DERIVATIVE; METHYLPSEUDOEPHEDRINE; NOREPHEDRINE; NORPSEUDOEPHEDRINE; PLANT EXTRACT; PROPIONIC ACID DERIVATIVE; PSEUDOEPHEDRINE; SIDA CORDIFOLIA EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; DIET SUPPLEMENTATION; GAS CHROMATOGRAPHY; ION MONITORING; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD;

ALKALOIDS; CALIBRATION; DIETARY SUPPLEMENTS; EPHEDRA; EPHEDRINE; FREEZING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 33747354977     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.02.043     Document Type: Article

References (32)

1. Pittler M.H., and Ernst E. Am. J. Clin. Nutr. 79 (2004) 529-536
2. Konno T., Taguchi T., Tamada M., and Hikino H. Phytochemistry 18 (1979) 697-698
3. Haller C.A., Jacob III P., and Benowitz N.L. Clin. Pharmacol. Ther. 71 (2002) 421-432
4. Sheu S.J. J. Food Drug Anal. 5 (1997) 285-294
5. Liu Y.M., Sheu S.J., Chiou S.H., Chang H.C., and Chen Y.P. Planta Med. 59 (1993) 376-378
6. Franzotti E.M., Santos C.V.F., Rodrigues S.L., Mourão R.H.V., Andrade M.R., and Antoniolli A.R. J. Ethnopharmacol. 72 (2000) 273-278
7. Ghosal S., Chauhan R.R.P.S., and Mehta R. Phytother. Chem. 14 (1975) 830-832
8. Gunatilaka A.A.L., Sotheeswaran S., Balasubramanian S., Chandrasckara A.I., and Sriyani H.T.B. Planta Med. 39 (1980) 66-72
9. Sander L.C., Sharpless K.E., Satterfield M.B., Ihara T., Phinney K.W., Yen J.H., Wise S.A., Gay M.L., Lam J.W., McCooeye M., Gardner G., Fraser C., Sturgeon R., and Roman M. Anal. Chem. 77 (2005) 3101-3112
10. Food and Drug Administration. Fed. Regist. 69 (2004) 6787-6854
11. Li H.X., Ding M.Y., Lu K., and Yu J.Y. J. Liq. Chromatogr. Related. Technol. 25 (2002) 313-320
12. Ganzera M., Lanser C., and Stuppner H. Talanta 66 (2005) 889-894
13. Ichikawa M., Udayama M., Imamura K., Shiraishi S., and Matsuura H. Chem. Pharm. Bull. 51 (2003) 635-639
14. Sullivan D., Wehrmann J., Schmitz J., Crowley R., and Eberhard J. J. AOAC Int. 86 (2003) 471-475
15. Jacob III P., Haller C.A., Duan M., Yu L., Peng M., and Benowitz N.L. J. Anal. Toxicol. 28 (2004) 152-159
16. Flurer C.L., Lin L.A., Satzger R.D., and Wolnik K.A. J. Chromatogr. B 669 (1995) 133-139
17. Phinney K.W., Ihara T., and Sander L.C. J. Chromatogr. A 1077 (2005) 90-97
18. Li H.X., Ding M.Y., Lv K., and Yu J.Y. J. Chromatogr. Sci. 39 (2001) 370-374
19. Betz J.M., Gay M.L., Mossoba M.M., Adams S., and Portz B.S. J. AOAC Int. 80 (1997) 303-317
20. Hansen L.B. J. Pharmacol. Sci. 90 (2001) 943-948
21. ICH Topic Q 2 B Validation of Analytical Procedures: Methodology, The European Agency for the evaluation of Medicinal Products, ICH Technical Coordination, London, 1996 (http://www.emea.eu.int/htms/human/ich/quality/ichfin.htm).
22. Guidance for Industry, Bioanalytical Method validation, US Department of Health and Human Services, Food and Drug Administration, May 2001 (http://www.fda.gov/cder/guidance/4252fnl.htm).
23. http://www.unodc.org
24. Zhang J.S., Tian Z., and Lou Z.C. Acta Pharm. Sinica 24 (1989) 865-871
25. Yamasaki K., Fujita K., Sakamoto M., Okada K., Yoshida K., and Tanaka O. Chem. Pharm. Bull. 22 (1974) 2898-2902
26. Cui J.F., Niu C.Q., and Zhang J.S. Acta Pharm. Sinica 26 (1991) 852-857
27. Krishna S., and Ghose T.P. J. Soc. Chem. Ind. 48 (1929) 67-70
28. Read B.E., and Feng C.T. J. Am. Pharm. Assoc. 17 (1928) 1189-1192
29. Feng C.T., and Read B.E. Chin. J. Physiol. 2 (1928) 337-344
30. Read B.E., and Feng C.T. Pharm. J. 119 (1927) 356-357
31. Hayden A.A., and Jordan C.B. J. Am. Pharm. Assoc. 22 (1933) 616-625
32. Shekelle P.G., Hardy M.L., Morton S.C., Maglione M., Mojica W.A., Suttorp M.J., Rhodes S.L., Jungvig L., and Gagne J. JAMA 289 (2003) 1537-1545