The effects of i.v. fentanyl administration on the minimum alveolar concentration of isoflurane in horses

British Journal of Anaesthesia

Volumn 97, Issue 2, 2006, Pages 232-237

  Thomasy, S M ^a   Steffey, E P ^b   Mama, K R ^c   Solano, A ^b   Stanley, S D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Veterinary Dentistry and Oral Surgery   (United States)

Author keywords

Anaesthetics volatile, isoflurane; Analgesics opioid, fentanyl; MAC, horse; Potency, anaesthetic

Indexed keywords

FENTANYL; ISOFLURANE; CENTRAL DEPRESSANT AGENT; INHALATION ANESTHETIC AGENT; INTRAVENOUS ANESTHETIC AGENT; NARCOTIC ANALGESIC AGENT;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INFUSION; DRUG POTENCY; FEMALE; HORSE; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STEADY STATE; VENOUS BLOOD; ANIMAL; ANIMAL DISEASE; BLOOD; CHEMISTRY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG ADMINISTRATION; DRUG INTERACTION; GENERAL ANESTHESIA; INTRAVENOUS DRUG ADMINISTRATION; LUNG ALVEOLUS; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL;

ADJUVANTS, ANESTHESIA; ANALGESICS, OPIOID; ANESTHESIA, GENERAL; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; FEMALE; FENTANYL; HORSES; INFUSIONS, INTRAVENOUS; ISOFLURANE; MALE; PULMONARY ALVEOLI;

EID: 33747341343     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael116     Document Type: Article

References (20)

1. Lehmann KA, Heinrich C, van Heiss R. Balanced anesthesia and patient-controlled postoperative analgesia with fentanyl: Minimum effective concentrations, accumulation and acute tolerance. Acta Anaesthesiol Belg 1988; 39: 11-23
2. Ilkiw JE. Balanced anesthetic techniques in dogs and cats. Clin Tech Small Anim Pract 1999; 14: 27-37
3. Ilkiw JE, Pascoe PJ, Hasking SC, Patz JD, Jaffe R. The cardiovascular sparing effect of fentanyl and atropine, administered to enflurane anesthetized dogs. Can J Vet Res 1994; 58: 248-53
4. McEwan AI, Smith C, Dyar O, Goodman D, Smith LR, Glass PS. Isoflurane minimum alveolar concentration reduction by fentanyl. Anesthesiology 1993; 78: 864-9
5. Hellyer PW, Mama KR, Shafford HL, Wagner AE, Kollias-Baker C. Effects of diazepam and flumazenil on minimum alveolar concentration for dogs anesthetized with isoflurane or a combination of isoflurane and fentanyl. Am J Vet Res 2001; 62: 555-60
6. Moon PF, Scarlett JM, Ludders JW, Conway TA, Lamb SV. Effect of fentanyl on the minimum alveolar concentration of isoflurane in swine. Anesthesiology 1995; 83: 535-42
7. Steffey EP, Eisele JH, Baggot JD. Interactions of morphine and isoflurane in horses. Am J Vet Res 2003; 64: 166-75
8. Pascoe PJ, Steffey EP, Black WD, Claxton JM, Jacobs JR, Woliner MJ. Evaluation of the effect of alfentanil on the minimum alveolar concentration of halothane in horses. Am J Vet Res 1993; 54: 1327-32
9. Thomasy SM, Slovis N, Maxwell LK, Kollias-Baker C. Transdermal fentanyl combined with non-steroidal anti-inflammatory drugs for analgesia in horses. J Vet Intern Med 2004; 18: 550-4
10. Maxwell LK, Thomasy SM, Slovis N, Kollias-Baker C. Pharmacokinetics of fentanyl following intravenous and transdermal administration in horses. Equine Vet J 2003; 35: 484-90
11. Steffey EP, Howland D, Giri S, Eger EI. Enflurane, halothane, and isoflurane potency in horses. Am J Vet Res 1977; 38: 1037-9
12. Thomasy SM, Mama KR, Whitley K, Steffey EP, Stanley SD. The influence of general anaesthesia on the pharmacokinetics of fentanyl and its primary metabolite in horses. Equine Vet J 2006. submitted
13. Kamerling SG, DeQuick DJ, Weckman TJ, Tobin T. Dose-related effects of fentanyl on autonomic and behavioral responses in performance horses. Gen Pharmacol 1985; 16: 253-8
14. Johnson CB, Taylor PM. Effects of alfentanil on the equine electroencephalogram during anaesthesia with halothane in oxygen. Res Vet Sci 1997; 62: 159-63
15. Steffey EP, Dunlop CI, Farver TB, Woliner MJ, Schultz LJ. Cardiovascular and respiratory measurements in awake and isoflurane-anesthetized horses. Am J Vet Res 1987; 48: 7-12
16. Steffey EP, Howland D. Comparison of circulatory and respiratory effects of isoflurane and halothane anesthesia in horses. Am J Vet Res 1980; 41: 821-5
17. Steffey EP, Hodgson DS, Dunlop CI, et al. Cardiopulmonary function during 5 hours of constant-dose isoflurane in laterally recumbent, spontaneously breathing horses. J Vet Pharmacol Ther 1987; 10: 290-7
18. Steffey EP, Eger EI. Hyperthermia and halothane MAC in the dog. Anesthesiology 1974; 41: 392-6
19. Eisele JH, Eger EI, Muallem M. Narcotic properties of carbon dioxide in the dog. Anesthesiology 1967; 28: 856-65
20. Whitehair KJ, Steffey EP, Willits NH, Wolinger MJ. Recovery of horses from inhalation anesthesia. Am J Vet Res 1993; 54: 1693-702