Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro

Acta Physiologica

Volumn 188, Issue 1, 2006, Pages 33-40

  Ewert, S ^a   Spak, E ^a,b   Olbers, T ^a   Johnsson, E ^a   Edebo, A ^a   Fandriks L ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Angiotensin receptors; Contraction; Renin angiotensin system; Small intestine; Smooth muscle

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II; ATROPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; GUANETHIDINE; LOSARTAN;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DUODENUM MOTILITY; FEMALE; HUMAN; HUMAN TISSUE; ILEUM CONTRACTION; IN VITRO STUDY; INTESTINE CONTRACTION; INTESTINE MUSCLE; INTESTINE WALL; ISOMETRICS; JEJUNUM; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMALL INTESTINE; WESTERN BLOTTING;

ADRENERGIC ANTAGONISTS; ADULT; AGED; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN II TYPE 2 RECEPTOR BLOCKERS; ANIMALS; ATROPINE; BLOTTING, WESTERN; CHOLINERGIC ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUANETHIDINE; HUMANS; IMIDAZOLES; INTESTINE, SMALL; LOSARTAN; MALE; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PYRIDINES; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; SPECIES SPECIFICITY;

EID: 33747252786     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2006.01600.x     Document Type: Article

References (28)

1. Beleslin, D.B. 1968. The effect of angiotensin on the peristaltic reflex of the isolated guinea-pig ileum. Br J Pharmacol 32, 583-90.
2. Berry, C., Touyz, R., Dominiczak, A.F., Webb, R.C. & Johns, D.G. 2001. Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide. Am J Physiol Heart Circ Physiol 281, H2337-65.
3. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-54.
4. Daniel, E.E., Kwan, C.Y. & Janssen, L. 2001. Pharmacological techniques for the in vitro study of intestinal smooth muscles. J Pharmacol Toxicol Methods 45, 141-58.
5. De Gasparo, M., Catt, K.J., Inagami, T., Wright, J.W. & Unger, T. 2000. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52, 415-72.
6. De Godoy, M.A. & De Oliveira, A.M. 2002. Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle. J Pharmacol Exp Ther 303, 333-9.
7. De Godoy, M.A., Dunn, S. & Rattan, S. 2004. Evidence for the role of angiotensin II biosynthesis in the rat internal anal sphincter tone. Gastroenterology 127, 127-38.
8. Ewert, S., Sjoberg, T., Johansson, B., et al. 2006. Dynamic expression of the angiotensin II type 2 receptor and duodenal mucosal alkaline secretion in the Sprague-Dawley rat. Exp Physiol 91, 191-9.
9. Fan, Y.P., Puri, R.N. & Rattan, S. 2002. Animal model for angiotensin II effects in the internal anal sphincter smooth muscle: mechanism of action. Am J Physiol Gastrointest Liver Physiol 282, G461-9.
10. Fishlock, D.J. & Gunn, A. 1970. The action of angiotensin on the human colon in vitro. Br J Pharmacol 39, 34-9.
11. Godfraind, T., Kaba, A. & Polster, P. 1966. Dissociation in two contractile components of the isolated guinea-pig ileum response to angiotensin. Arch Int Pharmacodyn Ther 163, 227-9.
12. Jin, X.H., Wang, Z.Q., Siragy, H.M., Guerrant, R.L. & Carey, R.M. 1998. Regulation of jejunal sodium and water absorption by angiotensin subtype receptors. Am J Physiol 275, R515-23.
13. Jin, X.H., Siragy, H.M., Guerrant, R.L. & Carey, R.M. 1999. Compartmentalization of extracellular cGMP determines absorptive or secretory responses in the rat jejunum. J Clin Invest 103, 167-74.
14. Johansson, B., Holm, M., Chen, L., et al. 1997. ANG II prolongs splanchnic nerve-mediated inhibition of duodenal mucosal alkaline secretion in the rat. Am J Physiol 273, R942-6.
15. Johansson, B., Holm, M., Ewert, S., et al. 2001. Angiotensin II type 2 receptor-mediated duodenal mucosal alkaline secretion in the rat. Am J Physiol Gastrointest Liver Physiol 280, G1254-60.
16. Levens, N.R. 1985. Control of intestinal absorption by the renin-angiotensin system. Am J Physiol 249, G3-15.
17. Ludtke, F.E., Golenhofen, K. & Schubert, F. 1989. Angiotensin II stimulates human gastric smooth muscle in vitro. J Auton Pharmacol 9, 139-47.
18. Macari, D., Bottari, S., Whitebread, S., De Gasparo, M. & Levens, N. 1993. Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat. Eur J Pharmacol 249, 85-93.
19. Nouet, S. & Nahmias, C. 2000. Signal transduction from the angiotensin II AT2 receptor. Trends Endocrinol Metab 11, 1-6.
20. Ozono, R., Wang, Z.Q., Moore, A.F., et al. 1997. Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension 30, 1238-46.
21. Rattan, S., Fan, Y.P. & Puri, R.N. 2002. Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles. Life Sci 70, 2147-64.
22. Sarna, S.K., Otterson, M.F., Ryan, R.P. & Cowles, V.E. 1993. Nitric oxide regulates migrating motor complex cycling and its postprandial disruption. Am J Physiol 265, G749-66.
23. Schinke, M., Doods, H.N., Ganten, D., Wienen, W. & Entzeroth, M. 1991. Characterization of rat intestinal angiotensin II receptors. Eur J Pharmacol 204, 165-70.
24. Shehadeh, Z., Price, W.E. & Jacobson, E.D. 1969. Effects of vasoactive agents on intestinal blood flow and motility in the dog. Am J Physiol 216, 386-92.
25. Silva, B.A., Nouailhetas, V.L. & Aboulafia, J. 1999. Desensitization to ANG II in guinea pig ileum depends on membrane repolarization: role of maxi-K(+) channel. Am J Physiol 277, C739-45.
26. Turker, R.K. & Ercan, Z.S. 1978. A comparative study with angiotensin II and (des-aspartic acid) -angiotensin II in the anesthetized cats. Res Commun Chem Pathol Pharmacol 21, 15-26.
27. Wang, G.D., Wang, X.Y., Hu, H.Z., et al. 2005. Angiotensin receptors and actions in guinea pig enteric nervous system. Am J Physiol Gastrointest Liver Physiol 289, G614-26.
28. Weekley, L.B. 1990. Rat duodenal smooth muscle contractile responses to angiotensin II are dependent on calmodulin. Clin Exp Pharmacol Physiol 17, 99-104.