Single-day therapy for recurrent genital herpes

American Journal of Clinical Dermatology

Volumn 7, Issue 4, 2006, Pages 209-211

  Tyring, Stephen ^a   Berger, Tim ^b   Yen Moore, Angela ^c   Tharp, Michael ^d   Hamed, Kamal ^e  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Arlington Center for Dermatology   (United States)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; FAMCICLOVIR; NUCLEOSIDE DERIVATIVE; PENCICLOVIR TRIPHOSPHATE; VALACICLOVIR;

CLINICAL FEATURE; CLINICAL TRIAL; DISEASE COURSE; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG INHIBITION; DRUG MECHANISM; DRUG SAFETY; GENITAL HERPES; HEADACHE; HEALING; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; LABORATORY TEST; PAIN; PATIENT COMPLIANCE; PRIORITY JOURNAL; PUBLIC HEALTH SERVICE; RECURRENT INFECTION; REVIEW; SYMPTOM; VIRUS REPLICATION;

2-AMINOPURINE; ANTIVIRAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HERPES GENITALIS; HUMANS; RECURRENCE;

EID: 33747202182     PISSN: 11750561     EISSN: 11750561     Source Type: Journal    
DOI: 10.2165/00128071-200607040-00001     Document Type: Review

References (20)

1. Malkin JE. Epidemiology of genital herpes simplex virus infection in developed countries. Herpes 2004; 11 Suppl. 1: 2A-23A
2. Apoola A, Radcliffe K. Antiviral treatment of genital herpes. Int J STD AIDS 2004; 15: 429-33
3. Brown ZA, Kern ER, Spruance SL, et al. Clinical and virologic course of herpes simplex genitalis. West J Med 1979 May; 130 (5): 414-21
4. Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex viruses. Clin Infect Dis 1998; 26: 541-55
5. Drob S, Loemer M, Lifshutz H. Genital herpes: the psychological consequences. Br J Med Psychol 1985; 58 (Pt 4): 307-15
6. Barton SE, Ebel CE, Kirchner JT, et al. The clinical management of recurrent genital herpes: current issues and future prospects. Herpes 2002 Apr; 9 (1): 15-20
7. Reitano M, Tyring S, Lang W, et al. Valaciclovir for the suppression of recurrent genital herpes simplex virus infection: a large-scale dose range-finding study. J Infect Dis 1998 Sep; 178 (3): 603-10
8. Diaz-Mitoma F, Sibbald G, Shafran SD, et al. Oral famciclovir for the suppression of recurrent genital herpes: a randomized controlled trial. JAMA 1998 Sep 9; 280 (10): 887-92
9. Corey L, Wald A, Patel R, et al. Once-daily valacyclovir to reduce the risk of transmission of genital herpes. N Engl J Med 2004 Jan 1; 350 (1): 11-20
10. Reichman RC, Badger GJ, Guinan ME, et al. Topically administered acyclovir in the treatment of recurrent herpes simplex genitalis: a controlled trial. J Infect Dis 1983 Feb; 147 (2): 336-40
11. Spruance SL, Rowe NH, Raborn GW, et al. Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: a double-blind, dose ranging, placebo-controlled, multicenter trial. J Infect Dis 1999; 179: 303-10
12. Reichman RC, Badger GJ, Mertz GJ, et al. Treatment of recurrent genital herpes simplex infections with oral acyclovir: a controlled trial. JAMA 1984 Apr 27; 251 (16): 2103-7
13. Wald A, Carrell D, Remington M, et al. Two-day regimen of acyclovir for treatment of recurrent genital herpes simplex virus type 2 infection. Clin Infect Dis 2002 Apr 1; 34 (7): 944-8
14. Leone PA, Trottier S, Miller JM. Valacyclovir for episodic treatment of genital herpes: a shorter 3-day treatment course compared with 5-day treatment. Clin Infect Dis 2002 Apr 1; 34 (7): 958-62
15. Tyring SK, Douglas Jr JM, Corey L, et al. A randomized, placebo-controlled comparison of oral valacyclovir and acyclovir in immunocompetent patients with recurrent genital herpes infections. The Valaciclovir International Study Group. Arch Dermatol 1998 Feb; 134 (2): 185-91
16. Pue MA, Benet MA. Pharmacokinetics of famciclovir in man. Antivir Chem Chemother 1993; 4 Suppl. 1: 47-55
17. Sacks S, Aoki F, Diaz-Mitoma F, et al. Patient-initiated, twice-daily oral famciclovir for early recurrent genital herpes. JAMA 1996 Jul; 276 (1): 44-9
18. Spruance SL. Herpes simplex labialis. In: Sacks SL, Straus SE, Whitley RJ, et al., editors. Clinical management of herpes viruses. Amsterdam: IOS Press, 1995: 3-42
19. Earnshaw DL, Bacon TH, Darlison SJ, et al. Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus. Antimicrob Agents Chemother 1992 Dec; 36 (12): 2747-57
20. Aoki FY, Tyring S, Diaz-Mitoma F, et al. Single-day, patient-initiated famciclovir therapy for recurrent genital herpes: a randomized, double blind, placebo-controlled trial. Clin Infect Disease 2006 Jan 1; 42 (1): 8-13