Organisation of B-cell receptors on the cell membrane

IEE Proceedings: Systems Biology

Volumn 153, Issue 5, 2006, Pages 401-404

  Iber, D ^a   Gruhn, T ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPOLYMERS; MOLECULAR BIOLOGY; PHYSIOLOGY; POLYMERIZATION;

ANERGIC CELLS; B-CELL RECEPTORS (BCRS); MEMBRANE ORGANISATION; OLIGOMERIC CLUSTERS; PHYSIOLOGICAL PARAMETERS;

CELL MEMBRANES;

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN M; OLIGOMER; POLYMER;

ARTICLE; B LYMPHOCYTE; CELL MEMBRANE; CELL SURFACE; CHEMICAL INTERACTION; CLONAL ANERGY; CLUSTER ANALYSIS; CONTROLLED STUDY; DENSITY; GENE MUTATION; MATHEMATICAL ANALYSIS; POLYMERIZATION; PREDICTION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS;

ANIMALS; B-LYMPHOCYTES; CELL MEMBRANE; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, STATISTICAL; RECEPTORS, ANTIGEN, B-CELL;

EID: 33747186463     PISSN: 17412471     EISSN: None     Source Type: Journal    
DOI: 10.1049/ip-syb:20060015     Document Type: Article

References (31)

1. Kouskoff, V., Famiglietti, S., Lacaud, G., Lang, P., and Rider, J.E.: Et al. 'Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses', J. Exp. Med., 1998, 188, p. 1453-1464
2. Batista, F., and Neuberger, M.: 'Affinity dependencies of the B cell response to antigen: A threshold, a ceiling and the importance of off-rate', Immunity, 1998, 8, p. 751-759
3. Seed, B.: 'Initiation of signal transduction by receptor aggregation: role of nonreceptor tyrosine kinases', Semin. Immunol., 1995, 7, p. 3-11
4. Sun, T., Clark, M.R., and Storb, U.: 'A point mutation in the constant region of Ig λ1 prevents normal B cell development due to defective BCR signaling', Immunity, 2002, 16, p. 245-255
5. Sotirellis, N., Johnson, T.M., Hibbs, M.L., Stanley, I.J., and Stanley, E.: Et al. 'Autophosphorylation induces autoactivation and a decrease in the Src homology 2 domain accessibility of the Lyn protein kinase', J. Biol. Chem., 1995, 270, p. 29773-29780
6. Schamel, W., and Reth, M.: 'Monomeric and oligomeric complexes of the B cell antigen receptor', Immunity, 2000, 13, p. 5-14
7. Matsuuchi, L., and Gold, M.R.: 'New views of BCR structure and organization', Curr. Opin. Immunol., 2001, 13, p. 270-277
8. Reth, M.: 'Hydrogen peroxide as second messenger in lymphocyte activation', Nat. Immunol., 2002, 3, p. 1129-1134
9. Johansen, F.E., Braathen, R., and Brandtzaeg, P.: 'Role of J chain in secretory immunoglobulin formation, Scand. J. Immunol., 2000, 52, p. 240-248
10. Goodnow, C.C., Crosbie, J., Adelstein, S., Lavoie, T.B., and Smith-Gill, S.J.: Et al. 'Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice', Nature, 1998, 334, p. 676-682 0028-0836
11. Goodnow, C., Brink, R., and Adams, E.: 'Breakdown of self-tolerance in anergic B lymphocytes', Nature, 1991, 352, p. 532-536 0028-0836
12. Goodnow, C.: 'Balancing immunDty and tolerance: deleting and tuning lymphocyte repertoires', Proc. Natl Acad. Sci. USA, 1996, 93, p. 2264-2271 0027-8424
13. Weintraub, B., Jun, J., Bishop, A., Shokat, K., and Thomas, M.: Et al. 'Entry of B cell receptor into signaling domains is inhibited in tolerant B cells', J. Exp. Med., 2000, 191, p. 1443-1448
14. Flory, P.: 'Principles of polymer chemistry', (Cornell University Press 1953)
15. van der Gucht, J.: 'Equilibrium polymers in solution and at interfaces', (Wageningen Universiteit 2004), PhD thesis
16. Bell, G.I., Dembo, M., and Bongrand, P.: 'Cell adhesion. Competition between nonspecific repulsion and specific bonding', Biophys. J., 1984, 45, p. 1051-1064 0006-3495
17. Moy, V.T., Jiao, Y., Hillmann, T., Lehmann, H., and Sano, T.: 'Adhesion energy of receptor-mediated interaction measured by elastic deformation', Biophys. J., 1999, 76, p. 1632-1638 0006-3495
18. Keizer, J.: 'Nonequilibrium statistical thermodynamics and the effect of diffusion on chemical reaction rates', J. Phys. Chem., 1982, 86, p. 5052-5067 0022-3654
19. Favier, B., Burroughs, N., Wedderburn, L., and Valitutti, S.: 'TCR dynamics on the surface of living cells', Int. Immunol., 2001, 13, p. 1525-1532
20. Li, R., Mitra, N., Gratkowski, H., Vilaire, G., and Litvinov, R.: Et al. 'Activation of integrin αIIbβ3 by modulation of transmembrane helix associations', Science, 2003, 300, p. 795-798 0036-8075
21. Zhang, M., and Varki, A.: 'Cell surface sialic acids do not affect primary CD22 interactions with CD45 and surface IgM nor the rate of constitutive CD22 endocytosis', Glycobiology, 2004, 14, p. 939-949
22. Vilen, B.J., Nakamura, T., and Cambier, J.C.: 'Antigen-stimulated dissociation of BCR mIg from Igα/Igβ: Implications for receptor desensitization', Immunity, 1999, 10, p. 239-248
23. Hombach, J., Tsubata, T., Leclercq, L., Stappert, H., and Reth, M.: 'Molecular components of the B-cell antigen receptor complex of the IgM class', Nature, 1990, 343, p. 760-762 0028-0836
24. Fuentes-Panana, E.M., Bannish, G., and Monroe, J.G.: 'Basal B-cell receptor signaling in B lymphocytes: Mechanisms of regulation and role in positive selection, differentiation, and peripheral survival', Immunol. Rev., 2004, 197, p. 26-40
25. Tolar, P., Sohn, H.W., and Pierce, S.K.: 'The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer', Nat. Immunol., 2005, 6, p. 1168-1176
26. Bell, S., and Goodnow, C.: 'A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes', EMBO J., 1994, 13, p. 816-826
27. Hartley, S., Crosbie, J., Brink, R., Kantor, A., and Basten, A.: Et al. 'Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens', Nature, 1991, 353, p. 765-769 0028-0836
28. Carrasco, Y.R., Fleire, S.J., Cameron, T., Dustin, M.L., and Batista, F.D.: 'LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation', Immunity, 2004, 20, p. 589-599
29. Vilen, B.J., Burke, K.M., Sleater, M., and Cambier, J.C.: 'Transmodulation of BCR signaling by transduction-incompetent antigen receptors: Implications for impaired signaling in anergic B cells', J. Immunol., 2002, 168, p. 4344-4351
30. Erikson, J., Radic, M.Z., Camper, S.A., Hardy, R.R., and Carmack, C.: Et al. 'Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice', Nature, 1991, 349, p. 331-334 0028-0836
31. Benschop, R.J., Aviszus, K., Zhang, X., Manser, T., and Cambier, J.C.: et al. 'Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive', Immunity, 2001, 14, p. 33-43