Experimental evidence for allosteric modifier saturation as predicted by the bi-substrate Hill equation

IEE Proceedings: Systems Biology

Volumn 153, Issue 5, 2006, Pages 342-345

  Hanekom, A J ^a   Hofmeyr, J H S ^a   Snoep, J L ^a   Rohwer, J M ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; ENZYMES; NUMERICAL ANALYSIS; REACTION KINETICS;

ALLOSTERIC MODIFIER SATURATION; BI-SUBSTRATE HILL EQUATION; BI-SUBSTRATE MONOD-WYMAN-CHANGEUX (MWC) EQUATION; MAXIMUM INHIBITORY EFFECT;

BIOLOGY;

PYRUVATE KINASE;

ALLOSTERISM; ARTICLE; CONCENTRATION (PARAMETERS); ENZYME INHIBITION; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SUBSTRATE; HILL EQUATION; IN VITRO STUDY; INTERMETHOD COMPARISON; MATHEMATICAL MODEL; MONOD WYMAN CHANGEUX EQUATION; PREDICTION;

CATALYSIS; COMPUTER SIMULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYMES; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; SUBSTRATE SPECIFICITY;

EID: 33747171484     PISSN: 17412471     EISSN: None     Source Type: Journal    
DOI: 10.1049/ip-syb:20060029     Document Type: Article

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