Mutational analysis of the intramembranous H10 loop of yeast Nhx1 reveals a critical role in ion homoeostasis and vesicle trafficking

Biochemical Journal

Volumn 398, Issue 1, 2006, Pages 97-105

  Mukherjee, Sanchita ^a,b   Kallay, Laura ^a   Brett, Christopher L ^a,c   Rao, Rajini ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Endosomal pH; Ion homoeostasis; Na+ H+ exchanger (NHE); Salt tolerance; Vesicle trafficking; Yeast Na+(K+) H + exchanger 1 (Nhx1)

Indexed keywords

BIOLOGICAL MEMBRANES; CORRELATION METHODS; MUTAGENESIS; PH EFFECTS; PLASMAS; TRANSPORT PROPERTIES;

ENDOSOMAL PH; ION HOMOEOSTASIS; NA+/H+ EXCHANGER (NHE); SALT TOLERANCE; VESICLE TRAFFICKING; YEAST NA+(K+)/H + EXCHANGER 1 (NHX1);

YEAST;

CARBOXYL GROUP; CARBOXYPEPTIDASE C; GLUTAMIC ACID; LEUCINE; PHENYLALANINE; PROTEIN; PROTEIN NHE6; PROTEIN NHE7; PROTEIN NHE9; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 3; SODIUM PROTON EXCHANGE PROTEIN 4; SODIUM PROTON EXCHANGE PROTEIN 5; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; FUNGAL STRAIN; GENE SEQUENCE; HOMEOSTASIS; ION EXCHANGE; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; PH; PHENOTYPE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; YEAST;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS, ACIDIC; CARBOXYPEPTIDASE C; CATION TRANSPORT PROTEINS; CELL MEMBRANE; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMEOSTASIS; HYDROGEN-ION CONCENTRATION; HYGROMYCIN B; ION TRANSPORT; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SODIUM-HYDROGEN ANTIPORTER; TRANSPORT VESICLES; VACUOLES;

MAMMALIA;

EID: 33747169125     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060388     Document Type: Article

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