Altered peptide ligands control type II collagen-reactive T cells from rheumatoid arthritis patients

Modern Rheumatology

Volumn 16, Issue 4, 2006, Pages 226-228

  Ohnishi, Yasuyuki ^a   Tsutsumi, Akito ^a   Matsumoto, Isao ^a   Goto, Daisuke ^a   Ito, Satoshi ^a   Kuwana, Masataka ^b   Uemura, Yasushi ^c   Nishimura, Yasuharu ^d   Sumida, Takayuki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SAITAMA MEDICAL UNIVERSITY   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Altered peptide ligand (APL); Antagonist; Rheumatoid arthritis (RA); T cells; Type II collagen

Indexed keywords

ALANINE; ALTERED PEPTIDE LIGAND; AMINO ACID; COLLAGEN TYPE 2; EPITOPE; GLYCINE; HLA DR ANTIGEN; LIGAND; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE CONTROL; HUMAN; HUMAN CELL; LYMPHOID CELL LINE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECEPTOR BLOCKING; RHEUMATOID ARTHRITIS; T LYMPHOCYTE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTHRITIS, RHEUMATOID; CELL DIVISION; CELL LINE; COLLAGEN TYPE II; HLA-A ANTIGENS; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 33747168521     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-006-0495-1     Document Type: Article

References (8)

1. MTD Magistris J Alexander M Coggeshall A Altman FCA Gaeta HM Grey 1992 Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor Cell 68 625-34 1739971 10.1016/0092-8674(92)90139-4
2. C Pfeiffer J Stein S Southwood H Ketelaar A Sette K Bottomly 1995 Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo J Exp Med 181 1569-74 7699337 1:CAS:528:DyaK2MXkslWntLc%3D 10.1084/ jem.181.4.1569
3. YZ Chen S Matsushita Y Nishimura 1996 Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide J Immunol 157 3783-90 8892606 1:CAS:528:DyaK28XmsF2nu7k%3D
4. Y Ohnishi A Tsutsumi T Sakamaki T Sumida 2003 T cell epitopes of type II collagen in HLA-DRB1*0101 or DRB1*0405-positive Japanese patients with rheumatoid arthritis Int J Mol Med 11 331-5 12579335 1:CAS:528:DC%2BD3sXhslKqt7Y%3D
5. FC Arnett SM Edworthy DA Bloch 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315-24 3358796 1:STN:280:BieC1M3nt1Q%3D
6. EF Rosloniec KB Whittington DM Zaller AH Kang 2002 HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) use the same anchor residues for binding an immunodominant peptide derived from human type II collagen J Immunol 168 253-9 11751969 1:CAS:528:DC%2BD38Xht1GltQ%3D%3D
7. M Fridkis-Hareli EF Rosloniec L Fugger JL Strominger 2000 Synthetic peptides that inhibit binding of the collagen type II 261-273 epitope to rheumatoid arthritis-associated HLA-DR1 and -DR4 molecules and collagen-specific T-cell response Human Immunol 61 640-50 1:CAS:528:DC%2BD3cXksFGjt70%3D 10.1016/S0198-8859(00)00126-9
8. LK Myers Y Sakurai B Tang X He EF Rosloniec JM Stuart 2002 Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice Arthritis Rheum 46 3369-77 12483744 1:CAS:528:DC%2BD3sXjslGhug%3D%3D 10.1002/art.10687