Embolic signals in unselected stroke patients: Prevalence and diagnostic benefit

Stroke

Volumn 37, Issue 8, 2006, Pages 2039-2043

  Poppert, Holger ^a   Sadikovic, Suwad ^a   Sander, Kerstin ^a   Wolf, Oliver ^a   Sander, Dirk ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cerebrovascular accident; Intracranial embolism; Ultrasonography; Ultrasonography, Doppler, transcranial

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT;

ADULT; ATHEROSCLEROSIS; BRAIN EMBOLISM; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE CLASSIFICATION; DOPPLER ECHOGRAPHY; FEASIBILITY STUDY; FEMALE; HEART VALVE PROSTHESIS; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MICROEMBOLISM; PRIORITY JOURNAL; REVIEW; SENSITIVITY ANALYSIS; STROKE; TIME SERIES ANALYSIS; TRANSIENT ISCHEMIC ATTACK; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CLASSIFICATION; COMPARATIVE STUDY; ECHOGRAPHY; EVALUATION; INCIDENCE; MIDDLE AGED; RETROSPECTIVE STUDY; STANDARD;

ADULT; AGED; ANTICOAGULANTS; ATHEROSCLEROSIS; CEREBROVASCULAR ACCIDENT; FEASIBILITY STUDIES; FEMALE; HUMANS; INCIDENCE; INTRACRANIAL EMBOLISM; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; RETROSPECTIVE STUDIES; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 33747157370     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000231644.47325.aa     Document Type: Review

References (28)

1. Molloy J, Markus HS. Asymptomatic embolization predicts stroke and TIA risk in patients with carotid artery stenosis. Stroke. 1999;30:1440-1443.
2. Siebler M, Nachtmann A, Sitzer M, Rose G, Kleinschmidt A, Rademacher J, Steinmetz H. Cerebral microembolism and the risk of ischemia in asymptomatic high-grade internal carotid artery stenosis. Stroke. 1995;26:2184-2186.
3. Valton L, Larrue V, le Traon AP, Massabuau P, Geraud G. Microembolic signals and risk of early recurrence in patients with stroke or transient ischemic attack. Stroke. 1998;29:2125-2128.
4. Censori B, Partziguian T, Casto L, Camerlingo M, Mamoli A. Doppler microembolic signals predict ischemic recurrences in symptomatic carotid stenosis. Acta Neurol Scand. 2000;101:327-331.
5. Goertler M, Blaser T, Krueger S, Hofmann K, Baeumer M, Wallesch CW. Cessation of embolic signals after antithrombotic prevention is related to reduced risk of recurrent arterioembolic transient ischaemic attack and stroke. J Neurol Neurosurg Psychiatry. 2002;72:338-342.
6. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of org 10172 in acute stroke treatment. Stroke. 1993;24:35-41.
7. Ringelstein EB, Droste DW, Babikian VL, Evans DH, Grosset DG, Kaps M, Markus HS, Russell D, Siebler M; International Consensus Group on Microembolus Detection. Consensus on microembolus detection by TCD. Stroke. 1998;29:725-729.
8. Kaposzta Z, Young E, Bath PM, Markus HS. Clinical application of asymptomatic embolic signal detection in acute stroke: a prospective study. Stroke. 1999;30:1814-1818.
9. Goertler M, Baeumer M, Kross R, Blaser T, Lutze G, Jost S, Wallesch CW. Rapid decline of cerebral microemboli of arterial origin after intravenous acetylsalicylic acid. Stroke. 1999;30:66-69.
10. Markus HS, Droste DW, Kaps M, Larrue V, Lees KR, Siebler M, Ringelstein EB. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. Circulation. 2005;111:2233-2240.
11. Droste DW, Dittrich R, Kemeny V, Schulte-Altedorneburg G, Ringelstein EB. Prevalence and frequency of microembolic signals in 105 patients with extracranial carotid artery occlusive disease. J Neurol Neurosurg Psychiatry. 1999;67:525-528.
12. Markus HS, Thomson ND, Brown MM. Asymptomatic cerebral embolic signals in symptomatic and asymptomatic carotid artery disease. Brain. 1995;118(Pt 4):1005-1011.
13. Siebler M, Sitzer M, Rose G, Bendfeldt D, Steinmetz H. Silent cerebral embolism caused by neurologically symptomatic high-grade carotid stenosis. Event rates before and after carotid endarterectomy. Brain. 1993;116:1005-1015.
14. van Zuilen EV, Moll FL, Vermeulen FE, Mauser HW, van Gijn J, Ackerstaff RG. Detection of cerebral microemboli by means of transcranial doppler monitoring before and after carotid endarterectomy. Stroke. 1995;26:210-213.
15. Grosset DG, Georgiadis D, Abdullah I, Bone I, Lees KR. Doppler emboli signals vary according to stroke subtype. Stroke. 1994;25:382-384.
16. Tong DC, Albers GW. Transcranial doppler-detected microemboli in patients with acute stroke. Stroke. 1995;26:1588-1592.
17. Daffertshofer M, Ries S, Schminke U, Hennerici M. High-intensity transient signals in patients with cerebral ischemia. Stroke. 1996;27:1844-1849.
18. Del Sette M, Angeli S, Stara I, Finocchi C, Gandolfo C. Microembolic signals with serial transcranial doppler monitoring in acute focal ischemic deficit. A local phenomenon? Stroke. 1997;28:1311-1313.
19. Serena J, Segura T, Castellanos M, Davalos A. Microembolic signal monitoring in hemispheric acute ischaemic stroke: A prospective study. Cerebrovasc Dis. 2000;10:278-282.
20. Markus H. Monitoring embolism in real time. Circulation. 2000;102:826-828.
21. Lund C, Rygh J, Stensrod B, Sandset PM, Brucher R, Russell D. Cerebral microembolus detection in an unselected acute ischemic stroke population. Cerebrovasc Dis. 2000;10:403-408.
22. Mackinnon AD, Aaslid R, Markus HS. Ambulatory transcranial doppler cerebral embolic signal detection in symptomatic and asymptomatic carotid stenosis. Stroke. 2005;36:1726-1730.
23. Markus HS, Ackerstaff R, Babikian V, Bladin C, Droste D, Grosset D, Levi C, Russell D, Siebler M, Tegeler C. Intercenter agreement in reading doppler embolic signals. A multicenter international study. Stroke. 1997;28:1307-1310.
24. Abbott AL, Chambers BR, Stork JL, Levi CR, Bladin CF, Donnan GA. Embolic signals and prediction of ipsilateral stroke or transient ischemic attack in asymptomatic carotid stenosis: a multicenter prospective cohort study. Stroke. 2005;36:1128-1133.
25. Eicke BM, Barth V, Kukowski B, Werner G, Paulus W. Cardiac microembolism: prevalence and clinical outcome. J Neurol Sci. 1996;136:143-147.
26. Forteza AM, Babikian VL, Hyde C, Winter M, Pochay V. Effect of time and cerebrovascular symptoms of the prevalence of microembolic signals in patients with cervical carotid stenosis. Stroke. 1996;27:687-690.
27. Babikian VL, Wijman CA, Hyde C, Cantelmo NL, Winter MR, Baker E, Pochay V. Cerebral microembolism and early recurrent cerebral or retinal ischemic events. Stroke. 1997;28:1314-1318.
28. Gao S, Wong KS, Hansberg T, Lam WW, Droste DW, Ringelstein EB. Microembolic signal predicts recurrent cerebral ischemic events in acute stroke patients with middle cerebral artery stenosis. Stroke. 2004;35:2832-2836.