-
1
-
-
0041830430
-
Genomics as a probe for disease biology
-
Burke W. Genomics as a probe for disease biology. N Engl J Med 2003; 349: 969-74.
-
(2003)
N Engl J Med
, vol.349
, pp. 969-974
-
-
Burke, W.1
-
2
-
-
33644849222
-
Heart disease and stroke statistics - 2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics - 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2006; 113: e85-151.
-
(2006)
Circulation
, vol.113
-
-
Thom, T.1
Haase, N.2
Rosamond, W.3
-
3
-
-
18544372620
-
A comprehensive linkage analysis for myocardial infarction and its related risk factors
-
Broeckel U, Hengstenberg C, Mayer B, et al. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet 2002; 30: 210-4.
-
(2002)
Nat Genet
, vol.30
, pp. 210-214
-
-
Broeckel, U.1
Hengstenberg, C.2
Mayer, B.3
-
4
-
-
0036094165
-
Genomewide linkage analysis of the acute coronary syndrome suggests a locus on chromosome 2
-
Harrap SB, Zammit KS, Wong ZY, et al. Genomewide linkage analysis of the acute coronary syndrome suggests a locus on chromosome 2. Arterioscler Thromb Vasc Biol 2002; 22: 874-8.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 874-878
-
-
Harrap, S.B.1
Zammit, K.S.2
Wong, Z.Y.3
-
5
-
-
10744233196
-
Premature myocardial infarction novel susceptibility locus on chromosome 1p34-36 identified by genomewide linkage analysis
-
Wang Q, Rao S, Shen GQ, et al. Premature myocardial infarction novel susceptibility locus on chromosome 1p34-36 identified by genomewide linkage analysis. Am J Hum Genet 2004; 74: 262-71.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 262-271
-
-
Wang, Q.1
Rao, S.2
Shen, G.Q.3
-
6
-
-
4143098058
-
A genomewide scan for early-onset coronary artery disease in 438 families: The GENECARD Study
-
Hauser ER, Crossman DC, Granger CB, et al. A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. Am J Hum Genet 2004; 75: 436-47.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 436-447
-
-
Hauser, E.R.1
Crossman, D.C.2
Granger, C.B.3
-
7
-
-
0026675062
-
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
-
Cambien F, Poirier O, Lecerf L, et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-4.
-
(1992)
Nature
, vol.359
, pp. 641-644
-
-
Cambien, F.1
Poirier, O.2
Lecerf, L.3
-
8
-
-
0029875770
-
A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis
-
Weiss EJ, Bray PF, Tayback M, et al. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med 1996; 334: 1090-4.
-
(1996)
N Engl J Med
, vol.334
, pp. 1090-1094
-
-
Weiss, E.J.1
Bray, P.F.2
Tayback, M.3
-
9
-
-
0032495540
-
Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction
-
Iacoviello L, Di Castelnuovo A, De Knijff P, et al. Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction. N Engl J Med 1998; 338: 79-85.
-
(1998)
N Engl J Med
, vol.338
, pp. 79-85
-
-
Iacoviello, L.1
Di Castelnuovo, A.2
De Knijff, P.3
-
10
-
-
0032495541
-
The role of a common variant of the cholesterol ester transfer protein gene in the progression of coronary atherosclerosis
-
Kuivenhoven JA, Jukema JW, Zwinderman AH, et al. The role of a common variant of the cholesterol ester transfer protein gene in the progression of coronary atherosclerosis. N Engl J Med 1998; 338: 86-93.
-
(1998)
N Engl J Med
, vol.338
, pp. 86-93
-
-
Kuivenhoven, J.A.1
Jukema, J.W.2
Zwinderman, A.H.3
-
11
-
-
0035960593
-
Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction
-
Topol EJ, McCarthy J, Gabriel S, et al. Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 2001; 104: 2641-4.
-
(2001)
Circulation
, vol.104
, pp. 2641-2644
-
-
Topol, E.J.1
McCarthy, J.2
Gabriel, S.3
-
12
-
-
0037069779
-
Prediction of the risk of myocardial infarction from polymorphisms in candidate genes
-
Yamada Y, Izawa H, Ichihara S, et al. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med 2002; 347: 1916-23.
-
(2002)
N Engl J Med
, vol.347
, pp. 1916-1923
-
-
Yamada, Y.1
Izawa, H.2
Ichihara, S.3
-
13
-
-
18744407845
-
Functional SNPs in the lymphotoxin-a gene that are associated with susceptibility to myocardial infarction
-
Ozaki K, Ohnishi Y, Iida A, et al. Functional SNPs in the lymphotoxin-a gene that are associated with susceptibility to myocardial infarction. Nat Genet 2002; 32: 650-4.
-
(2002)
Nat Genet
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
-
14
-
-
2342480580
-
Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro
-
Ozaki K, Inoue K, Sato H, et al. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro. Nature 2004; 429: 72-5.
-
(2004)
Nature
, vol.429
, pp. 72-75
-
-
Ozaki, K.1
Inoue, K.2
Sato, H.3
-
15
-
-
25444523242
-
Identification of four gene variants associated with myocardial infarction
-
Shiffman D, Ellis SG, Rowland CM, et al. Identification of four gene variants associated with myocardial infarction. Am J Hum Genet 2005; 77: 596-605.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 596-605
-
-
Shiffman, D.1
Ellis, S.G.2
Rowland, C.M.3
-
16
-
-
27744456947
-
High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population
-
Itoh Y, Mizuki N, Shimada T, et al. High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 2005; 57: 717-29.
-
(2005)
Immunogenetics
, vol.57
, pp. 717-729
-
-
Itoh, Y.1
Mizuki, N.2
Shimada, T.3
-
17
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Ser B 1995; 57: 289-300.
-
(1995)
J Royal Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
18
-
-
0030476385
-
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease
-
Deloughery TG, Evans A, Sadeghi A, et al. Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 1996; 94: 3074-8.
-
(1996)
Circulation
, vol.94
, pp. 3074-3078
-
-
Deloughery, T.G.1
Evans, A.2
Sadeghi, A.3
-
19
-
-
0029806746
-
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma J, Stampfer MJ, Hennekens CH, et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1996; 94: 2410-6.
-
(1996)
Circulation
, vol.94
, pp. 2410-2416
-
-
Ma, J.1
Stampfer, M.J.2
Hennekens, C.H.3
-
20
-
-
0030811670
-
Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene
-
Schwartz SM, Siscovick DS, Malinow MR, et al. Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene. Circulation 1997; 96: 412-7.
-
(1997)
Circulation
, vol.96
, pp. 412-417
-
-
Schwartz, S.M.1
Siscovick, D.S.2
Malinow, M.R.3
-
21
-
-
0029655724
-
Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
-
Kluijtmans LA, van den Heuvel LP, Boers GH, et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 1996; 58: 35-41.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 35-41
-
-
Kluijtmans, L.A.1
van den Heuvel, L.P.2
Boers, G.H.3
-
22
-
-
0029827313
-
Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation
-
Gallagher PM, Meleady R, Shields DC, et al. Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation. Circulation 1996; 94: 2154-8.
-
(1996)
Circulation
, vol.94
, pp. 2154-2158
-
-
Gallagher, P.M.1
Meleady, R.2
Shields, D.C.3
-
23
-
-
0030897112
-
Genetic polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H, Taguchi J, Kurihara H, et al. Genetic polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 1997; 95: 2032-6.
-
(1997)
Circulation
, vol.95
, pp. 2032-2036
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
-
24
-
-
0032763113
-
Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease
-
Mager A, Lalezari S, Shohat T, et al. Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease. Circulation 1999; 100: 2406-10.
-
(1999)
Circulation
, vol.100
, pp. 2406-2410
-
-
Mager, A.1
Lalezari, S.2
Shohat, T.3
-
25
-
-
0029968008
-
Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction: A case-control study
-
Schmitz C, Lindpaintner K, Verhoef P, et al. Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction: a case-control study. Circulation 1996; 94: 1812-4.
-
(1996)
Circulation
, vol.94
, pp. 1812-1814
-
-
Schmitz, C.1
Lindpaintner, K.2
Verhoef, P.3
-
26
-
-
0032555167
-
Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: The Atherosclerosis Risk in Communities (ARIC) Study
-
Folsom AR, Nieto FJ, McGovern PG, et al. Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 1998; 98: 204-10.
-
(1998)
Circulation
, vol.98
, pp. 204-210
-
-
Folsom, A.R.1
Nieto, F.J.2
McGovern, P.G.3
-
27
-
-
0032146855
-
A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: Results among U.S. men
-
Verhoef P, Rimm EB, Hunter DJ, et al. A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men. J Am Coll Cardiol 1998; 32: 353-9.
-
(1998)
J Am Coll Cardiol
, vol.32
, pp. 353-359
-
-
Verhoef, P.1
Rimm, E.B.2
Hunter, D.J.3
-
28
-
-
0037163849
-
MTHFR 677C→T polymorphism and risk of coronary heart disease: A meta-analysis
-
Klerk M, Verhoef P, Clarke R, et al. MTHFR 677C→T polymorphism and risk of coronary heart disease: a meta-analysis. J Am Med Assoc 2002; 288: 2023-31.
-
(2002)
J Am Med Assoc
, vol.288
, pp. 2023-2031
-
-
Klerk, M.1
Verhoef, P.2
Clarke, R.3
-
29
-
-
27744471516
-
Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate?
-
Lewis SJ, Ebrahim S, Smith GD. Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate? Br Med J 2005; 331: 1053-6.
-
(2005)
Br Med J
, vol.331
, pp. 1053-1056
-
-
Lewis, S.J.1
Ebrahim, S.2
Smith, G.D.3
-
30
-
-
0034601745
-
Lipoprotein lipase activity is associated with severity of angina pectoris
-
Kastelein JJP, Jukema JW, Zwinderman AH, et al. Lipoprotein lipase activity is associated with severity of angina pectoris. Circulation 2000; 102: 1629-33.
-
(2000)
Circulation
, vol.102
, pp. 1629-1633
-
-
Kastelein, J.J.P.1
Jukema, J.W.2
Zwinderman, A.H.3
-
31
-
-
0031008144
-
Genetic variant showing a positive interaction with β-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene
-
Groenemeijer BE, Hallman MD, Reymer PWA, et al. Genetic variant showing a positive interaction with β-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. Circulation 1997; 95: 2628-35.
-
(1997)
Circulation
, vol.95
, pp. 2628-2635
-
-
Groenemeijer, B.E.1
Hallman, M.D.2
Reymer, P.W.A.3
-
32
-
-
0033536024
-
Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis
-
Wittrup HH, Tybjærg-Hansen A, Nordestgaard BG. Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis. Circulation 1999; 99: 2901-7.
-
(1999)
Circulation
, vol.99
, pp. 2901-2907
-
-
Wittrup, H.H.1
Tybjærg-Hansen, A.2
Nordestgaard, B.G.3
-
33
-
-
0034907585
-
Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Que'bec Family Study
-
Ukkola O, Garenc C, Pérusse L, et al. Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Que'bec Family Study. Atherosclerosis 2001; 158: 199-206.
-
(2001)
Atherosclerosis
, vol.158
, pp. 199-206
-
-
Ukkola, O.1
Garenc, C.2
Pérusse, L.3
-
34
-
-
0030615232
-
Ser447stop mutation in lipoprotein lipase is associated with elevated HDL cholesterol levels in normolipidemic males
-
Kuivenhoven JA, Groenemeyer BE, Boer JMA, et al. Ser447stop mutation in lipoprotein lipase is associated with elevated HDL cholesterol levels in normolipidemic males. Arterioscler Thromb Vasc Biol 1997; 17: 595-9.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 595-599
-
-
Kuivenhoven, J.A.1
Groenemeyer, B.E.2
Boer, J.M.A.3
-
35
-
-
0028883699
-
Lipoprotein lipase gene polymorphisms: Associations with myocardial infarction and lipoprotein levels, the ECTIM study
-
Jemaa R, Fumeron F, Poirier O, et al. Lipoprotein lipase gene polymorphisms: associations with myocardial infarction and lipoprotein levels, the ECTIM study. J Lipid Res 1995; 36: 2141-6.
-
(1995)
J Lipid Res
, vol.36
, pp. 2141-2146
-
-
Jemaa, R.1
Fumeron, F.2
Poirier, O.3
-
36
-
-
0034966105
-
Lipoprotein lipase D9N, N291S and S447X polymorphisms: Their influence on premature coronary heart disease and plasma lipids
-
van Bockxmeer FM, Liu Q, Mamotte C, et al. Lipoprotein lipase D9N, N291S and S447X polymorphisms: their influence on premature coronary heart disease and plasma lipids. Atherosclerosis 2001; 157: 123-9.
-
(2001)
Atherosclerosis
, vol.157
, pp. 123-129
-
-
van Bockxmeer, F.M.1
Liu, Q.2
Mamotte, C.3
-
37
-
-
0035202533
-
Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: The Bogalusa heart study
-
Chen W, Srinivasan SR, Elkasabany A, et al. Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study. Atherosclerosis 2001; 159: 367-73.
-
(2001)
Atherosclerosis
, vol.159
, pp. 367-373
-
-
Chen, W.1
Srinivasan, S.R.2
Elkasabany, A.3
-
38
-
-
21644435380
-
Genetic variants of the lipoprotein lipase gene and myocardial infarction in the Central Valley of Costa Rica
-
Yang Y, Ruiz-Narvaez E, Niu T, et al. Genetic variants of the lipoprotein lipase gene and myocardial infarction in the Central Valley of Costa Rica. J Lipid Res 2004; 45: 2106-9.
-
(2004)
J Lipid Res
, vol.45
, pp. 2106-2109
-
-
Yang, Y.1
Ruiz-Narvaez, E.2
Niu, T.3
-
39
-
-
0031955802
-
Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: The European Atherosclerosis Research Study (EARS)
-
Humphries SE, Nicaud V, Margalef J, et al. Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS). Arterioscler Thromb Vase Biol 1998; 18: 526-34.
-
(1998)
Arterioscler Thromb Vase Biol
, vol.18
, pp. 526-534
-
-
Humphries, S.E.1
Nicaud, V.2
Margalef, J.3
-
40
-
-
0032914885
-
Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins
-
Henderson HE, Kastelein JJP, Zwinderman AH, et al. Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins. J Lipid Res 1999; 40: 735-43.
-
(1999)
J Lipid Res
, vol.40
, pp. 735-743
-
-
Henderson, H.E.1
Kastelein, J.J.P.2
Zwinderman, A.H.3
-
41
-
-
0030602890
-
Common sequence variants of lipoprotein lipase: Standardized studies of in vitro expression and catalytic function
-
Zhang H, Henderson H, Gagne SE, et al. Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function. Biochim Biophys Acta 1996; 1302: 159-66.
-
(1996)
Biochim Biophys Acta
, vol.1302
, pp. 159-166
-
-
Zhang, H.1
Henderson, H.2
Gagne, S.E.3
-
42
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 1993; 12: 4251-9.
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
43
-
-
0029890339
-
Isolation, characterization, and chromosomal mapping of the human insulin promoter factor I (IPF-1) gene
-
Inoue H, Riggs AC, Tanizawa Y, et al. Isolation, characterization, and chromosomal mapping of the human insulin promoter factor I (IPF-1) gene. Diabetes 1996; 45: 789-94.
-
(1996)
Diabetes
, vol.45
, pp. 789-794
-
-
Inoue, H.1
Riggs, A.C.2
Tanizawa, Y.3
-
44
-
-
0028149890
-
Insulin promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, et al. Insulin promoter-factor 1 is required for pancreas development in mice. Nature 1994; 371: 606-9.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
-
45
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V, et al. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 1997; 15: 106-10.
-
(1997)
Nat Genet
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
-
46
-
-
0031977918
-
Identification of a single nucleotide insertion polymorphism in the upstream region of the insulin promoter factor-1 gene: An association study with diabetes mellitus
-
Yamada K, Yuan X, Ishiyama S, et al. Identification of a single nucleotide insertion polymorphism in the upstream region of the insulin promoter factor-1 gene: an association study with diabetes mellitus. Diabetologia 1998; 41: 603-5.
-
(1998)
Diabetologia
, vol.41
, pp. 603-605
-
-
Yamada, K.1
Yuan, X.2
Ishiyama, S.3
-
47
-
-
0034454416
-
Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in Caucasians
-
Hansen L, Urioste S, Petersen HV et al. Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in Caucasians. J Clin Endocrinol Metab 2000; 85: 1323-6.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 1323-1326
-
-
Hansen, L.1
Urioste, S.2
Petersen, H.V.3
|