Single-molecule, motion-based DNA sequencing using rna polymerase

Science

Volumn 313, Issue 5788, 2006, Pages 801-

  Greenleaf, William J ^a   Block, Steven M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; GENETIC ENGINEERING; RNA;

BASE-PAIR LEVEL; RNA POLYMERASE; SINGLE-MOLECULE, MOTION-BASED DNA;

DNA SEQUENCES;

ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; CYTIDINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE; NANOPARTICLE; NUCLEOSIDE TRIPHOSPHATE; RNA POLYMERASE; URIDINE TRIPHOSPHATE;

DNA; ENZYME; ENZYME ACTIVITY; GENETIC ENGINEERING; MOLECULAR ANALYSIS; RNA;

ARTICLE; BACTERIAL GENOME; BASE PAIRING; CONDUCTANCE; DNA FLANKING REGION; DNA SEQUENCE; DNA TEMPLATE; DNA TRANSCRIPTION; ENZYME ACTIVITY; MOTION; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ADENOSINE TRIPHOSPHATE; BASE PAIRING; CYTIDINE TRIPHOSPHATE; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; GUANOSINE TRIPHOSPHATE; MOTION; SEQUENCE ANALYSIS, DNA; TEMPLATES, GENETIC; URIDINE TRIPHOSPHATE;

EID: 33747103461     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1130105     Document Type: Article

References (8)

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7. Materials and methods are available as supporting material on Science Online.
8. S.M.B. acknowledges NIH grant GM057035 for support.