Transformation of ciprofloxacin-resistant Neisseria gonorrhoeae gyrA, parE and porB1b genes

International Journal of Antimicrobial Agents

Volumn 28, Issue 3, 2006, Pages 206-211

  Lindbäck, Emma ^a   Islam, Sohidul ^a   Unemo, Magnus ^b   Lang, Camilla ^a   Wretlind, Bengt ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ciprofloxacin; GyrA; Neisseria gonorrhoeae; ParE; PorB

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CONTROLLED STUDY; GENE SEQUENCE; GENETIC TRANSFORMATION; MINIMUM INHIBITORY CONCENTRATION; MUTATION; NEISSERIA GONORRHOEAE; NONHUMAN; PARE GENE; PORB1B GENE; PRIORITY JOURNAL; SEROTYPE;

ANTI-BACTERIAL AGENTS; CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; NEISSERIA GONORRHOEAE; PORINS; TRANSFORMATION, BACTERIAL;

EID: 33747100564     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.04.003     Document Type: Article

References (32)

1. Moodley P., and Sturm A.W. Ciprofloxacin-resistant gonorrhoea in South Africa. Lancet 366 (2005) 1159
2. Ray K., Bala M., Kumari S., and Narain J.P. Antimicrobial resistance of Neisseria gonorrhoeae in selected World Health Organization Southeast Asia Region countries: an overview. Sex Transm Dis 32 (2005) 178-184
3. Centers for Disease Control and Prevention (CDC). Increases in fluoroquinolone-resistant Neisseria gonorrhoeae among men who have sex with men-United States, 2003; and revised recommendations for gonorrhea treatment, 2004. MMWR Morb Mortal Wkly Rep 53 (2004) 335-338
4. Dewi B.E., Akira S., Hayashi H., and Ba-Thein W. High occurrence of simultaneous mutations in target enzymes and MtrRCDE efflux system in quinolone-resistant Neisseria gonorrhoeae. Sex Transm Dis 31 (2004) 353-359
5. Poole K. Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria. Antimicrob Agents Chemother 44 (2000) 2233-2241
6. Tran J.H., and Jacoby G.A. Mechanism of plasmid-mediated quinolone resistance. Proc Natl Acad Sci USA 99 (2002) 5638-5642
7. Tran J.H., Jacoby G.A., and Hooper D.C. Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase. Antimicrob Agents Chemother 49 (2005) 118-125
8. Vereshchagin V.A., Ilina E.N., Malakhova M.V., et al. Fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Russia: molecular mechanisms implicated. J Antimicrob Chemother 53 (2004) 653-656
9. Trees D.L., Sandul A.L., Neal S.W., Higa H., and Knapp J.S. Molecular epidemiology of Neisseria gonorrhoeae exhibiting decreased susceptibility and resistance to ciprofloxacin in Hawaii, 1991-1999. Sex Transm Dis 28 (2001) 309-314
10. Lindbäck E., Rahman M., Jalal S., and Wretlind B. Mutations in gyrA, gyrB, parC, and parE in quinolone-resistant strains of Neisseria gonorrhoeae. APMIS 110 (2002) 651-657
11. Bauer F.J., Rudel T., Stein M., and Meyer T.F. Mutagenesis of the Neisseria gonorrhoeae porin reduces invasion in epithelial cells and enhances phagocyte responsiveness. Mol Microbiol 31 (1999) 903-913
12. Derrick J.P., Urwin R., Suker J., Feavers I.M., and Maiden M.C.J. Structural and evolutionary inference from molecular variation in Neisseria porins. Infect Immun 67 (1999) 2406-2413
13. Bygdeman S.M., Gillenius E.C., and Sandström E.G. Comparison of two different sets of monoclonal antibodies for the serological classification of Neisseria gonorrhoeae. In: Schoolnik G.K. (Ed). The pathogenic Neisseriae (1985), American Society for Microbiology, Washington, DC
14. Knapp J.S., Tam M.R., Nowinski R.C., Holmes K.K., and Sandström E.G. Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. J Infect Dis 150 (1984) 44-48
15. Unemo M., Olcén P., Berglund T., Albert J., and Fredlund H. Molecular epidemiology of Neisseria gonorrhoeae: sequence analysis of the porB gene confirms presence of two circulating strains. J Clin Microbiol 40 (2002) 3741-3749
16. Bash M.C., Zhu P., Gulati S., NcKnew D., Rice P., and Lynn F. por variable-region typing by DNA probe hybridization is broadly applicable to epidemiologic studies of Neisseria gonorrhoeae. J Clin Microbiol 43 (2005) 1522-1530
17. Unemo M., Olcén P., Jonasson J., and Fredlund H. Molecular typing of Neisseria gonorrhoeae isolates by pyrosequencing of highly polymorphic segments of the porB gene. J Clin Microbiol 42 (2004) 2926-2934
18. Cannon J.G., Klapper D.G., Blackman E.Y., et al. Genetic locus (nmp-1) affecting the principal outer membrane protein of Neisseria gonorrhoeae. J Bacteriol 143 (1980) 847-851
19. Danielsson D., Faruki H., Dyer D., and Sparling F. Recombination near the antibiotic resistance locus penB results in antigenic variation of gonococcal outer membrane protein I. Infect Immun 52 (1986) 529-533
20. Olesky M., Hobbs M., and Nicholas R.A. Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae. Antimicrob Agents Chemother 46 (2002) 2811-2820
21. Gill M.J., Al-Hattawi K., Robertson B.D., Easmon C.S.F., and Ison C.A. Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus. Antimicrob Agents Chemother 42 (1998) 2799-2803
22. Lindbäck E., Gharizadeh B., Ataker F., et al. DNA gyrase gene in Neisseria gonorrhoeae as indicator for resistance to ciprofloxacin and species verification. Int J STD AIDS 16 (2005) 142-147
23. Janda W.M., and Knapp J.S. Neisseria and Moraxella. In: Murray P.R., Baron E.J., Joergensen J.H., Pfaller M.A., and Yolken R.H. (Eds). Manual of clinical microbiology (2003), ASM Press, Washington, DC
24. Chapin K.C., and Murray P.R. Media. In: Murray P.R., Baron E.J., Pfaller M.A., Tenover F.C., and Yolken R.H. (Eds). Manual of clinical microbiology (1999), ASM Press, Washington, DC
25. El Amin N., Giske C.G., Jalal S., Keijser B., Kronvall G., and Wretlind B. Carbapenem resistance mechanisms in Pseudomonas aeruginosa: alterations of porin OprD and efflux proteins do not fully explain resistance patterns observed in clinical isolates. APMIS 113 (2005) 187-196
26. Neves P., Berkane E., Gameiro P., Winterhalter M., and de Castro B. Interaction between quinolones antibiotics and bacterial outer membrane porin OmpF. Biophys Chem 113 (2005) 123-128
27. Domenech-Sanchez A., Martínez-Martínez L., Hernández-Allés S., et al. Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance. Antimicrob Agents Chemother 47 (2003) 3332-3335
28. Fudyk T.C., Maclean I.W., Simonsen N., et al. Genetic diversity and mosaicism at the por locus of Neisseria gonorrhoeae. J Bacteriol 181 (1999) 5591-5599
29. Giles J.A., Falconio J., Yuenger J.D., Zenilman J.M., Dan M., and Bash M. Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies. J Infect Dis 189 (2004) 2085-2093
30. Cooke S.J., de la Paz H., Poh L.C., Ison C.A., and Heckels J.E. Variation within serovars of Neisseria gonorrhoeae detected by structural analysis of outer-membrane protein PIB and by pulsed-field gel electrophoresis. Microbiology 143 (1997) 1415-1422
31. Unemo M., Olcén P., Albert J., and Fredlund H. Comparison of serologic and genetic porB-based typing of Neisseria gonorrhoeae: consequences for future characterization. J Clin Microbiol 41 (2003) 4141-4147
32. Rouquette-Loughlin C., Dunham S.A., Kuhn M., Balthazar T., and Shafer W.M. The NorM efflux pump of Neisseria gonorrhoeae and Neisseria meningitidis recognizes antimicrobial cationic compounds. J Bacteriol 185 (2003) 1101-1106