Pattern of mRNA expression of β-defensins in basal cell carcinoma

BMC Cancer

Volumn 6, Issue , 2006, Pages

  Gambichler, T ^a   Skrygan, M ^a   Huyn, J ^a   Bechara, F G ^a   Sand, M ^a   Altmeyer, P ^a   Kreuter, A ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; MESSENGER RNA; POLYPEPTIDE ANTIBIOTIC AGENT;

ADULT; AGED; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BASAL CELL CARCINOMA; CANCER CLASSIFICATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; MALE; PATHOGENESIS; PILOT STUDY; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; SEQUENCE ANALYSIS; SKIN BIOPSY; TISSUE DISTRIBUTION;

ADULT; AGED; AGED, 80 AND OVER; BETA-DEFENSINS; CARCINOMA, BASAL CELL; COMPUTER SYSTEMS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN NEOPLASMS;

EID: 33747098185     PISSN: 14712407     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-6-163     Document Type: Article

References (21)

1. Rubin AI, Chen EH, Ratner D: Basal-cell carcinoma. N Engl J Med 2005, 353:2262-2269.
2. Daya-Grosjean L, Couve-Privat S: Sonic hedgehog signaling in basal cell carcinomas. Cancer Lett 2005, 225:181-92.
3. Iftner A, Klug SJ, Garbe C, Blum A, Stancu A, Wilczynski SP, Iftner T: The prevalence of human papillomavirus genotypes in non-melanoma skin cancers of nonimmunosuppressed individuals identifies high-risk genital types as possible risk factor. Cancer Res 2003, 63:7515-7519.
4. Izadpanath A, Gallo RL: Antimicrobial peptides. J Am Acad Dermatol 2005, 52:381-390.
5. Yoshimoto T, Yamaai T, Mizukawa N, Sawaki IC, Nakano M, Yamachika E, Sugahara T: Different expression patterns of beta-defensins in human squamous cell carcinomas. Anticancer Res 2003, 23:4629-4633.
6. Arimura Y, Ashitani J, Yanagi S, Tokojima M, Abe K, Makue H, Nakazato M: Elevated serum beta-defensins concentrations in patients with lung cancer. Anticancer Res 2004, 24:4051-4057.
7. Donald CD, Sun CQ, Lim SD, Macoska J, Cohen C, Amin MB, Young AN, Ganz TA, Marshall FF, Petros JA: Cancer-specific loss of beta-defensin I in renal and prostatic carcinomas. Lab Invest 2003, 83:501-505.
8. Shnitsar VM, Lisovskiy IL, Soldatkina MA, Nespryadko SV, Turchak OV, Vinnitskaya AB, Pogrebniy PV: Human beta-defensin 3 (hBD-3) expression in A431 cell line and human vulval tumors. Exp Oncol 2004, 26:328-330.
9. Abiko Y, Miamura J, Nishimura M, Muramatsu T, Inoue T, Shimono M, Kaku T: Pattern of expression of beta-defensins in oral squamous cell carcinoma. Cancer Lett 1999, 143:37-43.
10. Giulietti A, Overbergh L, Valckx D, Decallone B, Bouillon R, Mathieu C: An Overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 2001, 25:386-401.
11. T Method. Methods 2001, 25:402-408.
12. Albrethsen J, Bogebo R, Gammeltoft S, Olsen J, Winther B, Raskov H: Upregulated expression of human neutrophil peptides 1, 2 and 3 (HNP 1-3) in colon cancer serum and tumours: a biomarker study. BMC Cancer 2005, 5:8.
13. Mizukawa N, Sugiyama K, Kamio M, Yamachika E, Ueno T, Fukunaga J, Takagi S, Sugahara T: Immunohistochemical staining of human alpha-defensin-1 (HNP-1), in the submandibular glands of patients with oral carcinomas. Anticancer Res 2000, 20(2B):1125-1127.
14. Muller CA, Markovic-Lipkovski J, Klatt T, Gamper J, Schwarz G, Beck H, Deeg M, Kalbacher H, Widmann S, Wessels JT, Becker V, Muller GA, Flad T: Human alpha-defensins HNPs-1, -2, and -3 in renal cell carcinoma: influences on tumor cell proliferation. Am J Pathol 2002, 160:1311-24.
15. de Jongh GJ, Zeeuwen PL, Kucharekova M, Pfundt R, van der Valk PG, Blokx W, Dogan A, Hiemstra PS, van de Kerkhof PC, Schalkwijk J: High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis. J Invest Dermatol 2005, 125:1163-1173.
16. Gambichler T, Skrygan M, Tomi NS, Altmeyer P, Kreuter A: Changes of antimicrobial peptide mRNA expression in atopic eczema following phototherapy. Br J Dermatol in press.
17. Zucht HD, Grabowski J, Schrader M, Liepke C, Jurgens M, Schulu-Knappe P, Forstmann WG: Human beta-defensin-1: a urinary peptide present in variant molecular forms and its putative functional implication. Eur J Med Res 1998, 3:315-323.
18. Kuzmina N, Talme T, Lapins J, Emtestam L: Non-invasive preoperative assessment of basal cell carcinoma of nodular and superficial types. Skin Res Technol 2005, 11:196-200.
19. Jappe U, Petzoldt D, Wendt C: Methicillin-resistant Staphylococcus aureus colonization in inflammatory versus non-inflammatory skin diseases: who should be screened? Acta Derm Venereol 2004, 84:181-186.
20. Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, Anderson M, Schroder JM, Wang JM, Howard OM, Oppenheim JJ: Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999, 286(5439):525-528.
21. Sawaki K, Yamaai T, Mizukawa N, Yoshimoto T, Ueno T, Nakano M, Sugahara T: Mortality of human epidermal keratinocytes in co-culture with oral squamous cell carcinoma cells. Anticancer Res 2003, 23(1A):79-84.