Epidemiology and costs of severe sepsis in Madrid. A hospital discharge study;Epidemiología y costes de la sepsis grave en Madrid. Estudio de altas hospitalarias

Medicina Intensiva

Volumn 30, Issue 5, 2006, Pages 197-203

  Inigo J ^a   Sendra, J M ^b   Diaz R ^c   Bouza, C ^d,e   Sarria Santamera A ^b,d  

^a Consejería de Sanidad y Consumo ^*  (Spain)

^b Red de Investigación de Resultados y Servicios Sanitarios IRYSS   (Spain)

^c HOSPITAL SEVERO OCHOA   (Spain)

^d Instituto de Salud Carlos III ^*  (Spain)

^e UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Epidemiology; Severe sepsis; Spain

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANDIDA; CHILD; CONTROLLED STUDY; COST OF ILLNESS; DEMOGRAPHY; DESCRIPTIVE RESEARCH; DISEASE SEVERITY; ESCHERICHIA COLI; FEMALE; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INCIDENCE; INFANT; INFECTION; LENGTH OF STAY; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; MORTALITY; MULTIPLE ORGAN FAILURE; NEWBORN; POPULATION BASED CASE CONTROL STUDY; SEPSIS; SPAIN; STREPTOCOCCUS;

EID: 33747069997     PISSN: 02105691     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0210-5691(06)74507-7     Document Type: Article

References (31)

1. Wheeler AP, Bernard GR. Treating patients with severe sepsis. N Engl J Med. 1999;340:207-14.
2. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992;101:1644-55.
3. Rangel-Frausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel RP. The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA. 1995; 273:117-23.
4. Wenzel RP. Treating sepsis. N Engl J Med. 2002;347:966-7.
5. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, López-Rodríguez A, et al, for the recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001;344:699-709.
6. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348:1546-54.
7. Pinner RW, Teutsch SM, Simonsen L, Klug LA, Graber JM, Clarke MJ, et al. Trends in infectious diseases mortality in the United States. JAMA. 1996;275:189-93.
8. Bernard GR, Wheeler AP, Russell JA, Schein R, Summer WR, Steinberg KP, et al. The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. N Engl J Med. 1997;336:912-8.
9. Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, et al, for the KyberSept Trial Study Group. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. JAMA. 2001;286:1869-78.
10. Sands KE, Bates DW, Lanken PN, Graman PS, Hibberd PL, Kahn KL. et al. Epidemiology of sepsis syndrome in 8 academic medical centers. Academic Medical Center Consortium Sepsis Project Working Group. JAMA. 1997;278:234-40.
11. Davies A, Green C, Mutton J, Chinn C. Severe sepsis: a European estimate of the burden of disease in ICU. Intensive Care Med. 2001;27:581A.
12. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29:1303-10.
13. Watson RS, Carcillo JA, Linde-Zwirble WT, Clermont G. Lidicker J, Angus DC. The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med. 2003; 167:695-701.
14. Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995; 23:1638-52.
15. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-83.
16. Ollendorf DA, Fendrick AM, Massey K, Williams GR, Oster G. Is sepsis accurately coded on hospital bills? Value Health. 2002;5:79-81.
17. Vincent JL, Opal S, Torres A, Bonten M, Cohen J, Wunderink R. The PIRO concept: I is for infection. Crit Care. 2003; 7:252-5.
18. Alberti C, Brun-Buisson C, Burchardi H, Martin C, Goodman S, Artigas A, et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med. 2002;28:108-21.
19. Gerlach H, Keh D. Recent progress in sepsis epidemiology-have we learned enough? Crit Care. 2003;7:333-4.
20. Sendra JM, Sarría-Santamera A, Iñigo J, Regidor E. Factores asociados a la mortalidad intrahospitalaria del infarto agudo de miocardio. Resultados de un estudio observacional. Med Clin (Barc). 2005;125:641-6.
21. Flaaten H. Epidemiology of sepsis in Norway in 1999. Crit Care. 2004;8:180-4.
22. Esteban A, Frutos-Vivar F, Ferguson ND, Gordo F, Honrubia T, Peñuelas O, et al. Incidence and outcomes of sepsis in an health area from Madrid, Spain. Am J Respir Crit Care Med. 2004;169:A846.
23. Nin N, Lorente JA, Ortiz-Leyba C, Valenzuela F, Baigorri F, López Rodríguez A, et al, por la Red para el Estudio del Shock y la Sepsis (RESYS). Estudio multicéntrico sobre la asociación entre variables relacionadas con la resucitación y la mortalidad en sepsis grave. Med Intensiva. 2005;29:212-8.
24. Brun-Buisson C, Meshaka P, Pinton P, Vallet B, for the EPISEPSIS Study Group. EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units. Intensive Care Med. 2004;30:580-8.
25. Finfer S, Bellomo R, Lipman J, French C, Dobb G, Myburgh J. Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med. 2004;30:589-96.
26. Padkin A, Goldfrad C, Brady AR, Young D, Black N, Rowan K. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland. Crit Care Med. 2003;31:2332-8.
27. Silva E, de Almeida PM, Beltrami AC, Mohovic T, de Oliveira CL, Janiszewski M, et al, for the Brazilian sepsis epidemiological study. Brazilian sepsis epidemiologic study. Crit Care. 2004;8:R251-R60.
28. Sundararajan V, Macisaac CM, Presneill JJ, Cade JF, Visvanathan K. Epidemiology of sepsis in Victoria, Australia. Crit Care Med. 2005;33:71-80.
29. Guidet B, Aegerter P, Gauzit R, Meshaka P, Dreyfuss D, for the CUB-Rea Study Group. Incidence and impact of organ dysfunctions associated with sepsis. Chest. 2005;127:942-51.
30. Burchardi H, Schneider H. Economic aspects of severe sepsis: a review of intensive care unit costs, cost of illness and cost effectiveness of therapy. Pharmacoeconomics. 2004;22:793-813.
31. Moerer O, Schmid A, Hofmann M, Herklotz A, Reinhart K, Werdan K, et al. Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use. Intensive Care Med. 2002;28:1440-6.