Rescue of corpus luteum function with peri-ovulatory HCG supplementation in IVF\ICSI GnRH antagonist cycles in which ovulation was triggered with a GnRH agonist: A pilot study

Reproductive BioMedicine Online

Volumn 13, Issue 2, 2006, Pages 173-178

  Humaidan, Peter ^a   Bungum, L ^a   Bungum, M ^a   Andersen, C Yding ^b  

^a VIBORG HOSPITAL   (Denmark)

^b Mental Health Services CPH   (Denmark)

Author keywords

GnRH agonist; GnRH antagonist; HCG; IVF; Ovulation induction

Indexed keywords

BUSERELIN; CHORIONIC GONADOTROPIN; ESTROFEM; GANIRELIX; INHIBIN A; PROGESTERONE; RECOMBINANT FOLLITROPIN;

ADULT; ARTICLE; BOLUS INJECTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORPUS LUTEUM FUNCTION; FEMALE; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; LUTEAL PHASE; OVULATION INDUCTION; PILOT STUDY; PREGNANCY OUTCOME; PREGNANCY RATE; PROGESTERONE BLOOD LEVEL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE;

EID: 33747059580     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60612-8     Document Type: Article

References (30)

1. Albano C, Smitz J, Camus M et al. 1997 Comparison of different doses of gonadotropin-releasing hormone antagonist Cetrorelix during controlled ovarian hyperstimulation. Fertility and Sterility 67, 917-922.
2. Babayof R, Margalioth E J, Huleihel M et al. 2006 Serum inhibin A, VEGF and TNF levels after triggering oocyte maturation with GnRH agonist compared with HCG in women with polycystic ovaries undergoing IVF treatment: a prospective randomised trial. Human Reproduction 21, 1260-1265.
3. Balasch J, Fabregues F, Tur R et al. 1995 Further characterization of the luteal phase inadequacy after gonadotrophin-releasing hormone agonist-induced ovulation in gonadotrophin-stimulated cycles. Human Reproduction 10, 1377-1381.
4. Balasch J, Tur R, Creus M et al. 1994 Triggering of ovulation by a gonadotropin releasing hormone agonist in gonadotropin-stimulated cycles for prevention of ovarian hyperstimulation syndrome and multiple pregnancy. Gynecology and Endocrinology 8, 7-12.
5. Emperaire JC, Parneix I, Ruffie A 2004 Luteal phase defects following agonist-triggered ovulation: a patient-dependent response. Reproductive BioMedicine Online 9, 22-27.
6. European Orgalutran® Study Group, Borm G Mannaerts B 2000 Treatment with the gonadotropin-releasing hormone antagonist ganirelix in women undergoing controlled ovarian hyperstimulation with recombinant follicle stimulating hormone is effective, safe and convenient: results of a controlled, randomized, multicentre trial. Human Reproduction 15, 1490-1498.
7. Fujiwara H, Ueda M, Hattori N et al. 1996 A differentiation antigen of human large luteal cells in corpora lutea of the menstrual cycle and early pregnancy. Biology of Reproduction 54, 1173-1183.
8. Fujiwara H, Fukuoka M, Yasuda K et al. 1994 Cytokines stimulate dipeptidyl peptidase-IV expression on human luteinizing granulosa cells. Journal of Clinical Endocrinology and Metabolism 79, 1007-1011.
9. Gonen Y, Balakier H, Powell W et al. 1990 Use of GnRH agonist to trigger follicular maturation for in vitro fertilization. Journal of Clinical Endocrinology and Metabolism 71, 918-922.
10. Greenwald GS, Terranova PF 1988 Follicular selection and its control. In: Knobil E, Neill JD (eds) The Physiology of Reproduction. Raven Press, New York, pp. 387-446.
11. Hattori N, Ueda M, Fujiwara H et al. 1995 Human luteal cells express leukocyte functional antigen (LFA)-3. Journal of Clinical Endocrinology and Metabolism 80, 78-84.
12. Hoff JD, Quigley ME, Yen SS 1983 Hormonal dynamics at midcycle: a revaluation. Journal of Clinical Endocrinology and Metabolism 57, 792-796.
13. Humaidan P, Ejdrup Bredkjær H, Bungum L et al. 2005 GnRH agonist (Buserelin) or HCG for ovulation induction in GnRH antagonist IVF/ICSI cycles: a prospective randomised study. Human Reproduction 20, 1213-1220.
14. Imoedemhe DA, Sigue AB, Pacpaco EL et al. 1991 Stimulation of endogenous surge of luteinizing hormone with gonadotropin-releasing hormone analogue after ovarian stimulation for in vitro fertilization. Fertility and Sterility 55, 328-332.
15. Itskovitz-Eldor J, Kol S, Mannaerts B et al. 1998 Case report: first established pregnancy after controlled ovarian hyperstimulation with recombinant follicle stimulating hormone and gonadotrophin-releasing hormone antagonist ganirelix (Org 37462). Human Reproduction 13, 295-295.
16. Itskovitz J, Boldes R, Levron J et al. 1991 Induction of preovulatory luteinizing hormone surge and prevention of ovarian hyperstimulation syndrome by gonadotropin-releasing hormone agonist. Fertility and Sterility 56, 213-220.
17. Kauma SW 2000 Cytokines in implantation. Journal of Reproduction and Fertility Suppl. 55, 31-42.
18. Kitajima Y, Endo T, Manase K et al. 2004 Gonadotropin-releasing hormone agonist administration reduced vascular endothelial growth factor (VEGF), VEGF receptors, and vascular permeability of the ovaries of hyperstimulated rats. Fertility and Sterility 81 (Suppl. 1), 842-849.
19. Kol S, Muchtar M 2005 Recombinant gonadotrophin-based, ovarian hyperstimulation syndrome-free stimulation of the high responder: suggested protocol for further research. Reproductive BioMedicine Online 10, 575-577.
20. Kolibianakis EM, Schultze-Mosgau A, Schroer A et al. 2005 A lower ongoing pregnancy rate can be expected when GnRH agonist is used for triggering final oocyte maturation instead of HCG in patients undergoing IVF with GnRH antagonists. Human Reproduction 10, 2887-2892.
21. Latouche J, Crumeyrolle-Arias M, Jordan D et al. 1989 GnRH receptors in human granulosa cells: anatomical localization and characterization by autoradiographic study. Endocrinology 125, 1739-1741.
22. Lindhard A, Bentin-Ley U, Ravn V et al. 2002 Biochemical evaluation of endometrial function at the time of implantation. Fertility and Sterility 78, 221-233.
23. Minaretzis D, Jakubowski M, Mortola JF et al. 1995 Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells. Journal of Clinical Endocrinology and Metabolism 80, 430-434.
24. Nakano R, Mizuno T, Kotsuji F et al. 1973 'Triggering' of ovulation after infusion of synthetic luteinizing hormone releasing factor (LRF). Acta Obstetrica et Gynecologica Scandinavica 52, 269-272.
25. Peñarrubia J, Balasch J, Fábregues F et al. 1998 Human chorionic gonadotrophin luteal support overcomes luteal phase inadequacy after gonadotrophin-releasing hormone agonist-induced ovulation in gonadotrophin-stimulated cycles. Human Reproduction 13, 3315-3318.
26. Revel A, Casper RF 2001 The use of LHRH agonists to induce ovulation. Infertility and Reproductive Medicine Clinics of North America 12, 105-118.
27. Romeu A, Monzo A, Peiro T et al. 1997 Endogenous LH surge versus HCG as ovulation trigger after low-dose highly purified FSH in IUI: a comparison of 761 cycles. Journal of Assisted Reproduction and Genetics 14, 518-524.
28. Segal S, Casper RF 1992 Gonadotropin-releasing hormone agonist versus human chorionic gonadotropin for triggering follicular maturation in in vitro fertilization. Fertility and Sterility 57, 1254-1258.
29. Shalev E, Geslevich Y, Matilsky M et al. 1995 Gonadotrophin-releasing hormone agonist compared with human chorionic gonadotrophin for ovulation induction after clomiphene citrate treatment. Human Reproduction 10, 2541-2544.
30. Wang TH, Horng SG, Chang CL et al. 2002 Human chorionic gonadotropin-induced ovarian hyperstimulation syndrome is associated with up-regulation of vascular endothelial growth factor. Journal of Clinical Endocrinology and Metabolism 87, 3300-3308.