Bilirubin kinetic modeling for quantification of extracorporeal liver support

Blood Purification

Volumn 24, Issue 4, 2006, Pages 413-422

  Jung, Aleksandra ^a,b   Krisper, Peter ^a   Haditsch, Bernd ^a   Stauber, Rudolf E ^a   Trauner, Michael ^a   Holzer, Herwig ^a   Schneditz, Daniel ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Poland)

Author keywords

Bilirubin generation; Compartment modeling; Parameter identification

Indexed keywords

BILIRUBIN GLUCURONIDE; HEPARIN; PROSTACYCLIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMPARTMENT MODEL; FEMALE; HUMAN; KINETICS; LIVER FAILURE; LIVER SUPPORT; MALE; PRIORITY JOURNAL; SOLUTE;

AGED; BILIRUBIN; EXTRACORPOREAL CIRCULATION; FEMALE; HUMANS; LIVER FAILURE; LIVER, ARTIFICIAL; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; TREATMENT OUTCOME;

EID: 33747041927     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094575     Document Type: Article

References (23)

1. Mitzner SR, Stange J, Klammt S, Peszynski P, Schmidt R: Albumin dialysis using the molecular adsorbent recirculating system. Curr Opin Nephrol Hypertens 2001;10:777-783.
2. Rifai K, Ernst T, Kretschmer U, Bahr MJ, Schneider A, Hafer C, Haller H, Manns MP, Fliser D: Prometheus: a new extracorporeal system for the treatment of liver failure. J Hepatol 2003;39:984-990.
3. Awad SS, Swaniker F, Magee J, Punch J, Bartlett RH: Results of a phase I trial evaluating a liver support device utilizing albumin dialysis. Surgery 2001;130:354-362.
4. McIntyre CW, Pluck RJ, Freeman JG, Lambie SH: Characterization of treatment dose delivered by albumin dialysis in the treatment of acute renal failure associated with severe hepatic dysfunction. Clin Nephrol 2002;58:376-383.
5. Stange J, Hassanein TI, Mehta RL, Mitzner SR, Bartlett RH: The molecular adsorbents recycling system as a liver support system based on albumin dialysis: a summary of preclinical investigations, prospective, randomized, controlled clinical trial, and clinical experience from 19 centers. Artif Organs 2002;26:103-110.
6. Depner TA: Prescribing Hemodialysis: A Guide to Urea Modeling. Boston, Kluwer Academic Publishers, 1991.
7. Schneditz D, Daugirdas JT: Compartment effects in hemodialysis. Semin Dial 2001;14:271-277.
8. Gotch FA, Sargent JA: A mechanistic analysis of the National Cooperative Dialysis Study (NCDS). Kidney Int 1985;28:526-534.
9. Fulop M, Sandson J, Brazeau P: Dialyzability, protein binding, and renal excretion of plasma conjugated bilirubin. J Clin Invest 1965;44:666-680.
10. Ahlfors CE: Measurement of plasma unbound unconjugated bilirubin. Anal Biochem 2000;279:130-135.
11. Patzer II JF, Bane SE: Bound solute dialysis. ASAIO J 2003;3:271-281.
12. Berk PD, Howe RB, Bloomer JR, Berlin N: Studies of bilirubin kinetics in normal adults. J Clin Invest 1969;48:2176-2190.
13. Bankhead MM, Toto RD, Star RA: Accuracy of urea removal estimated by kinetic models. Kidney Int 1995;48:785-793.
14. Casino FG, Gaudiano V, Santarsia G, Ambrosecchia R, Mostacci SD, Bagnato C, Lopez T: Reconciliation between urea kinetics and direct dialysis quantification. Nephrol Dial Transplant 1992;7:1007-1012.
15. Krause A: Prometheus: a new extracorporeal liver support therapy; in Arroyo V, Forns X, Garcia-Pagan JC, Rodes J (eds): Progress in the Treatment of Liver Diseases. Ars Medica, 2003, pp 437-443.
16. Krisper P, Haditsch B, Stauber R, Jung A, Stadibauer V, Trauner M, Holzer H, Schneditz D: In vivo quantification of liver dialysis: comparison of albumin dialysis and fractionated plasma separation. J Hepatol 2005;43:451-457.
17. Stiller S, Xu XQ, Gruner N, Vienken J, Mann H: Validation of a two-pool model for the kinetics of beta2-microglobulin. Int J Artif Organs 2002;25:411-420.
18. Evenepoel P, Laleman W, Wilmer A, Claes K, Maes B, Kuypers D, Bammens B, Nevens F, Vanrenterghem Y: Detoxifying capacity and kinetics of Prometheus: a new extracorporeal system for the treatment of liver failure. Blood Purif 2005;23:349-358.
19. Gotch FA, Keen ML: Kinetic modeling in hemodialysis; in Nissenson AR, Fine RN (eds): Clinical Dialysis. New York, McGraw-Hill, 2005, pp 153-202.
20. Grandi F, Avanzolini G, Cappello A: Sensitivity analysis for estimating urea kinetics parameters during hemodialysis. Med Eng Phys 1995;17:177-181.
21. Jung A, Krisper P, Haditsch B, Stauber R, Holzer H, Schneditz D: Bilirubin kinetics in extracorporeal liver support. Int J Artif Organs 2004;27:588.
22. Ellmerer M, Schaupp L, Brunner GA, Sendlhofer G, Wutte A, Wach P, Pieber TR: Measurement of interstitial albumin in human skeletal muscle and adipose tissue by open-flow microperfusion. Am J Physiol Endocrinol Metab 2000;278:E352-356.
23. Daugirdas JT: Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. J Am Soc Nephrol 1993;4:1205-1213.