Venezuelan equine encephalitis virus complex-specific monoclonal antibody provides broad protection, in murine models, against airborne challenge with viruses from serogroups I, II and III

Virus Research

Volumn 120, Issue 1-2, 2006, Pages 107-112

  Phillpotts, R J ^a  

^a Biomedical Sciences   (United Kingdom)

Author keywords

Airborne infection; Monoclonal antibody; Passive immunisation; Venezuelan equine encephalitis

Indexed keywords

FC RECEPTOR; GLYCOPROTEIN E; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

AIRBORNE INFECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARBOVIRUS; ARTICLE; BLOOD GROUP TYPING; DRUG MECHANISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROVOCATION TEST; RECEPTOR BINDING; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; BIOTERRORISM; CELLS, CULTURED; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; ENCEPHALOMYELITIS, VENEZUELAN EQUINE; FIBROBLASTS; IMMUNIZATION, PASSIVE; INJECTIONS, INTRAPERITONEAL; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; VIRAL ENVELOPE PROTEINS;

ALPHAVIRUS; MURINAE; VEEV COMPLEX; VENEZUELAN EQUINE ENCEPHALITIS VIRUS;

EID: 33747015784     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2006.02.003     Document Type: Article

References (31)

1. Alevizatos A., McKinney R.W., and Feigin R.D. Live, attenuated Venezuelan equine encephalomyelitis vaccine. Am. J. Trop. Med. Hyg. 16 (1967) 762-768
2. Berge T.O., Banks I.S., and Tiggert W.D. Attenuation of Venezuelan equine encephalomyelitis virus by in vitro cultivation in guinea pig heart cells. Am. J. Hyg. 73 (1961) 209-218
3. Casamassima A.C., Hess L.W., and Marty A. TC83 Venezuelan encephalitis exposure during pregnancy. Teratology 36 (1987) 287-289
4. Dimmock N.J. Update on the neutralisation of animal viruses. Rev. Med. Virol. 5 (1995) 165-179
5. Garcia-Tamayo J. Effecto teratogenico del virus de la encefalitis equina Venezolana, una revision del problema. Invest. Clin. 33 (1992) 81-86
6. Guyton A.C. Measurement of the respiratory volume of laboratory animals. Am. J. Physiol. 150 (1947) 10-11
7. Hawley R.J., and Eitzen Jr. E.M. Biological weapons-a primer for microbiologists. Ann. Rev. Microbiol. 55 (2001) 235-253
8. Hilleman M.R. Overview: cause and prevention in biowarfare and bioterrorism. Vaccine 20 (2002) 3055-3067
9. Johnson K.M., and Martin D.H. Venezuelan equine encephalitis. Adv. Vet. Sci. Comp. Med. 18 (1974) 79-116
10. Johnston R.E., and Peters C.J. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Field's Virology. 3rd ed. (1995), Lippincott-Raven, New York P843-P898
11. Klietmann W.F., and Ruoff K.L. Bioterrorism: implications for the clinical microbiologist. Clin. Mcrobiol. Rev. 14 (2001) 364-381
12. Mathews J.H., and Roehrig J.T. Determination of the protective epitopes on the glycoproteins of Venezuelan equine encephalomyelitis virus by passive transfer of monoclonal antibodies. J. Immunol. 129 (1982) 2763-2767
13. Mathews J.H., Roehrig J.T., and Trent D.W. Role of complement and the Fc portion of immunoglobulin G in immunity Venezuelan equine encephalomyelitis virus infection with glycoprotein-specific monoclonal antibodies. J. Virol. 55 (1985) 594-600
14. Oliphant T., Engle M., Nybakken G., Doane C., Johnson S., Ling H., Gorlatov S., Mehthop E., Marri A., Chung K.M., Ebel G., Kramer L.D., Freemont D.H., and Diamond M.S. Development of a humanised monoclonal antibody with therapeutic potential against West Nile virus. Nat. Med. 11 (2005) 522-530
15. Phillpotts R.J., Brooks T.B., and Cox C.S. A simple device for exposure of animals to infectious microorganisms by the airborne route. J. Epidemiol. Infect. 118 (1997) 71-75
16. Phillpotts R.J., Jones L.D., and Howard S.C. Monoclonal antibody protects mice against infection and disease when given either before or up to 24 h after airborne challenge with virulent Venezuelan equine encephalitis virus. Vaccine 20 (2002) 1497-1504
17. Pittman P.R., Makuch R.S., Mangiafico J.A., Cannon T.L., Gibbs P.H., and Peters C.J. Long-term duration of detectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine. Vaccine 14 (1996) 337-343
18. Pratt W.D., Gibbs P., Louise M., Pitt M., and Schmaljohn A.L. Use of telemetry to assess vaccine-induced protection against parenteral and aerosol infections of Venezuelan equine encephalitis virus in non-human primates. Vaccine 16 (1998) 1056-1064
19. Pratt W.D., Davis N.L., Johnston R.E., and Smith J.F. Genetically engineered, live attenuated vaccines for Venezuelan equine encephalitis: testing in animal models. Vaccine 21 (2003) 3854-3862
20. Rayfield E.J., Gorelkin L., Cumow R.T., and Jahrling P.B. Virus-induced pancreatid disease induced by Venezuelan equine encephalitis virus. Alterations in glucose tolerance and insulin release. J. Am. Diabetes Assoc. 25 (1976) 621-623
21. Rico-Hesse R., Roehrig J.T., and Dickerman R. Monoclonal antibodies define antigenic variation in the ID variety of Venezuelan equine encephalitis virus. Am. J. Trop. Med. Hyg. 38 (1988) 187-194
22. Roehrig J.T., Day J.W., and Kinney R.M. Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies. Virology 118 (1982) 269-278
23. Roehrig J.T., and Mathews J.H. The neutralization site on the E2 glycoprotein of Venezuelan equine encephalomyelitis (TC-83) virus is composed of multiple conformationally stable epitopes. Virology 142 (1985) 347-356
24. Roehrig J.T., Hunt A.R., Kinney R.M., and Mathews J.T. In vitro mechanisms of monoclonal antibody Neutralisation of alphaviruses. Virology 165 (1988) 66-73
25. Roehrig J.T., and Bolin R.A. Monoclonal antibodies capable of distinguishing epizootic from enzootic varieties of subtype I Venezuelan equine encephalitis viruses in a rapid indirect immunofluorescence assay. J. Clin. Microbiol. 35 (1997) 1887-1890
26. Steele K.E., Davis K.J., Stephan K., Kell W., Vogel P., and Hart M.K. Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice. Vet. Pathol. 35 (1998) 386-397
27. Strauss J.H., and Strauss E.G. The alphaviruses: gene expression, replication and evolution. Microbiol. Rev. 58 (1994) 491-562
28. The Subcommittee on Arbovirus Laboratory Safety of the American Committee on Arthropod-borne viruses. Laboratory safety for arborviruses and certain other viruses of vertebrates. Am. J. Trop. Med. Hyg. 29 (1980) 1359-1381
29. Weaver S.C., Ferro C., Barrera R., Boshell J., and Navarro J.C. Venezuelan equine encephalitis. Ann. Rev. Entomol. 49 (2004) 141-174
30. Wenger F. Necrosis cerebra massiva del feto en casos de encefalitis equina Venezolana. Invest. Clin. 21 (1967) 13-31
31. Wright A.W., and Phillpotts R.J. Humane endpoints are an objective measure of morbidity in Venezuelan encephalomyelitis virus infection of mice. Arch. Virol. 143 (1998) 1-8