CRT improves the exercise capacity and functional reserve of the failing heart through enhancing the cardiac flow- and pressure-generating capacity

European Journal of Heart Failure

Volumn 8, Issue 5, 2006, Pages 515-521

  Schlosshan, D ^a   Barker, D ^a   Pepper, C ^b   Williams, G ^b   Morley, C ^c   Tan, L B ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

^c BRADFORD ROYAL INFIRMARY   (United Kingdom)

Author keywords

Cardiac function; Cardiac power output; Cardiac resynchronisation therapy; Exercise capacity; Heart failure

Indexed keywords

ADULT; AGED; ARTERIAL PRESSURE; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CARDIOPULMONARY EXERCISE TEST; CLINICAL ARTICLE; CORONARY ARTERY BLOOD FLOW; DISEASE SEVERITY; EXERCISE; FEMALE; HEART FAILURE; HEART OUTPUT MEASUREMENT; HEART PERFORMANCE; HEART VENTRICLE PRESSURE; HEMODYNAMIC MONITORING; HUMAN; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROGNOSIS; QRS COMPLEX;

AGED; CARDIAC OUTPUT; CARDIAC PACING, ARTIFICIAL; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; FOLLOW-UP STUDIES; HEALTH STATUS INDICATORS; HEART FAILURE; HEART FAILURE, CONGESTIVE; HEART RATE; HUMANS; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; PACEMAKER, ARTIFICIAL; PROSPECTIVE STUDIES; QUALITY OF LIFE; VASCULAR RESISTANCE;

EID: 33746990668     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2005.11.002     Document Type: Article

References (27)

1. Cleland J.G., Daubert J.C., Erdmann E., et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med 352 15 (2005) 1539-1549
2. Abraham W.T., Fisher W.G., Smith A.L., et al. Cardiac resynchronization in chronic heart failure. N Engl J Med 346 24 (2002) 1845-1853
3. Bradley D.J., Bradley E.A., Baughman K.L., et al. Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. JAMA 289 6 (2003) 730-740
4. Bristow M.R., Krause-Steinrauf H., Nuzzo R., et al. Cardiac-resynchronisation therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med 350 21 (2004) 2140-2150
5. Leclercq C., Cazeau S., Le Breton H., et al. Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure. J Am Coll Cardiol 32 7 (1998) 1825-1831
6. Nelson G.S., Berger R.D., Fetics B.J., et al. Left ventricular or biventricular pacing improves cardiac function at diminished energy cost in patients with dilated cardiomyopathy and left bundle-branch block. Circulation 102 25 (2000) 3053-3059
7. Cotter G., Williams S.G., Vered Z., and Tan L.B. Role of cardiac power in heart failure. Curr Opin Cardiol 18 3 (2003) 215-222
8. Tan L.B., Littler W.A., and Murray R.G. Beneficial haemodynamic effects of intravenous dopexamine in patients with low-output heart failure. J Cardiovasc Pharmacol 10 3 (1987) 280-286
9. Gregoratos G., Abrams J., Epstein A.E., et al. ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices-summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). J Am Coll Cardiol 40 9 (2002) 1703-1719
10. Cooke G.A., Marshall P., Al Timman J.K., et al. Physiological cardiac reserve: development of a non-invasive method and first estimates in man. Heart 79 3 (1998) 289-294
11. Elborn J.S., Stanford C.F., and Nicholls D.P. Reproducibility of cardiopulmonary parameters during exercise in patients with chronic cardiac failure. The need for a preliminary test. Eur Heart J 11 1 (1990) 75-81
12. Hobbs F.D., Kenkre J.E., Roalfe A.K., Davis R.C., Hare R., and Davies M.K. Impact of heart failure and left ventricular systolic dysfunction on quality of life: a cross-sectional study comparing common chronic cardiac and medical disorders and a representative adult population. Eur Heart J 23 23 (2002) 1867-1876
13. Meaney E., Alva F., Moguel R., Meaney A., Alva J., and Webel R. Formula and nomogram for the sphygmomanometric calculation of the mean arterial pressure. Heart 84 (2000) 64
14. Tan L.B. Clinical and research implications of new concepts in the assessment of cardiac pumping performance in heart failure. Cardiovasc Res 21 8 (1987) 615-622
15. Tan L.B. Evaluation of cardiac dysfunction, cardiac reserve and inotropic response. Postgrad Med J 67 Suppl 1 (1991) S10-S20
16. Cohen-Solal A., Tabet J.Y., Logeart D., et al. A non-invasively determined surrogate of cardiac power (circulatory power) at peak exercise is a powerful prognostic factor in chronic heart failure. Eur Heart J 23 (2002) 806-814
17. Chua T.P., Ponikowski P., Harrington D., et al. Clinical correlates and prognostic significance of the ventilatory response to exercise in chronic heart failure. J Am Coll Cardiol 29 7 (1997) 1585-1590
18. Cowburn P.J., Patel H., Jolliffe R.E., Wald R.W., and Parker J.D. Cardiac resynchronisation therapy: an option for inotrope-supported patients with end-stage heart failure?. Eur J Heart Fail 7 2 (2005) 215-217
19. Yu C.M., Chau E., Sanderson J.E., et al. Tissue Doppler echocardiographic evidence of reverse remodeling and improved synchronicity by simultaneously delaying regional contraction after biventricular pacing therapy in heart failure. Circulation 105 4 (2002) 438-445
20. Mansourati J., Etienne Y., Gilard M., et al. Left ventricular-based pacing in patients with chronic heart failure: comparison of acute hemodynamic benefits according to underlying heart disease. Eur J Heart Fail 2 2 (2000) 195-199
21. Duncan A., Wait D., Gibson D., and Daubert J.C. Left ventricular remodelling and haemodynamic effects of multisite biventricular pacing in patients with left ventricular systolic dysfunction and activation disturbances in sinus rhythm: sub-study of the MUSTIC (Multisite Stimulation in Cardiomyopathies) trial. Eur Heart J 24 5 (2003) 430-441
22. Leclercq C., and Kass D.A. Retiming the failing heart: principles and current clinical status of cardiac resynchronization. J Am Coll Cardiol 39 2 (2002) 194-201
23. Popovic Z.B., Grimm R.A., Perlic G., et al. Noninvasive assessment of cardiac resynchronization therapy for congestive heart failure using myocardial strain and left ventricular peak power as parameters of myocardial synchrony and function. J Cardiovasc Electrophysiol 13 12 (2002) 1203-1208
24. Lamp B., Vogt J., Schmidt H., and Horstkotte D. Impact of cardiopulmonary exercise testing on patient selection for cardiac resynchronisation therapy. Eur Heart J Suppl (D) (2004) D5-D9
25. Molhoek S.G., Bax J.J., van Erven L., et al. Atrial and brain natriuretic peptides as markers of response to resynchronisation therapy. Heart 90 1 (2004) 97-98
26. Grassi G., Vincenti A., Brambilla R., et al. Sustained sympathoinhibitory effects of cardiac resynchronization therapy in severe heart failure. Hypertension 44 5 (2004) 727-731
27. Williams S.G., Cooke G.A., Wright D.J., et al. Peak exercise cardiac power output; a direct indicator of cardiac function strongly predictive of prognosis in chronic heart failure. Eur Heart J 22 16 (2001) 1496-1503