Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton

Brazilian Archives of Biology and Technology

Volumn 44, Issue 3, 2001, Pages 263-267

  Santos Ricardo, Kelly Fabiane ^a   De Oliveira, Tânia Toledo ^a   Nagem, Tanus Jorge ^b   Da Silva Pinto, Aloisio ^a   Oliveira, Maria Goreti Almeida ^a   Soares, José Francisco ^c  

^a FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^b FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Cholesterol; Cholesterol HDL; Hyperlipidemic; Lipid; Morin; Nicotinic Acid; Quercetin; Rats; Triacylglycerols

Indexed keywords

EID: 33746989630     PISSN: 15168913     EISSN: 15168913     Source Type: Journal    
DOI: 10.1590/s1516-89132001000300007     Document Type: Article

References (28)

1. Affana's, E. V. I. B.;. Dorozkvo, A. I.; Brodskii, A. V.; Kostyuk, V. A, and Potapovitch, A. I. (1989), Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem. Pharmacol; 38: 1763-1769.
2. Cavallini, L.; Bindoli, A. and Siliprandi, N. (1978), Comparative evaluation of antiperoxidative action of silymarin and other flavonoids. Pharmacol. Res. Commun. 10, 133-136
3. 4-induced microssomal lipid peroxidation. Experientia. 47, 195-199
4. De Whalley, C. V.; Rankin, S. M.; Hoult, J. R.; Jessup, W. and Leake, D. S. (1990), Flavonoids inhibit the oxidative modification of low density lypoproteins by macrophages. Biochem. Pharmacol. 39, 1743-1750
5. Fraga, C. G.; Martino, V. S.; Ferraro, G. E.; Coussio, J. D. and Boveris, A. (1987), Flavonoids as antioxidants evaluated by in vitro and in situ liver chemiluminescence. Biochem. Pharmacol. 36, 717-720
6. Frankel, E. N.; Kanner, J.; German, J. B.; Parks, E. and Kinsella, J.E. (1993), Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet. 341, 454-457
7. Gryglewski, R. J.; Korbut, R.; Robak, J. and Swies, J. (1987), On the mechanisms of antithrombotic action of flavonois. Biochem. Pharmacol. 36, 317-322
8. Hanasaki, Y.; Ogawa, S. and Fukui, S. (1994), The correlation between active oxygens scavenging and antioxidative effects of flavonoids free radical. Biol. Med. 16: 845-850
9. a Ed. I: 226-228
10. Hope, W. C.; Welton, A. F.; Fielder-Nagy, C.; Batula-Bernardo, C. and Coffey, J. W. (1983), In vitro inhibition of the biosynthesis of slow reacting substance of anaphylaxis (SRS-A) and lipoxygenase activity of quercetin. Biochem. Pharmacol. 32, 367-371
11. Husain, S. R.; Cillard, J. and Cillard, P. (1987), Hydroxyl radical scavenging activity of flavonoids. Phytochemistry 26, 2489-2491
12. Ishikawa, T.; Fidge, N. (1979), Changes in the concentration of plasma lipoproteins and apoproteins following the administration of Triton WR 1339 to rats. Journal of Lip. Res. 20, 254-264
13. Jahromi, M. A. F. and Ray, A. B. (1993), Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium. Journal of Natural Products. 56 (7), 989-994
14. Kato, N. and Tosa, N. (1983), Effects of Dietary Quercetin on Serum Lipids. J. Agric. Biol. Chem. 47 (9), 2119-2120
15. Kellner, A.; Correl, W. J.; Ladd, A. T. (1951), Susteined hyperlipemia induced in rabbits by means of intravenously injected surface active agents. J. Exp. Med. 93, 373-385
16. Lackeman, G. M.; Claeys, M.; Wan Gabo, P. G. R.; Herman, A. G. and Vlein Tink, A. (1986), Planta Medica 52, 433-436
17. Leite, P. F. (1994), Risco Cardiovascular: Fatores metabólicos e nutricionais, diagnósticos e tratamento. Loyola Ed. São Paulo, 1-33
18. a ed., Guanabara Koogan, Rio de Janeiro, 47-115
19. Maggio, G. D. (1956), Azione della quercetina sull'andamento de alcuni Processi patologici sperimentali correlati alla Mallatia arteriosclerótica. Rehivio italiano di science farmacologiche. 28-37
20. Mora, A.; Paya, M.; Rios, J. L. and Alcaraz, M. J. (1990), Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem. Pharmacol. 40, 793-797
21. Morel, I.; Lescoat, G.; Cogrel, P.; Sergent, O.; Pasdeloup, N.; Brissot, P.; Cillard, P. and Cillard, J. (1993) Antioxidant and iron chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures. Biochem. Pharmacol. 45, 13-19
22. Ratty, A. K. and Das, N. P. (1988) Effects of flavonoids on non-enzymic lipid peroxidation: structure activity relationship. Biochem. Med. Metabol. Biol. 39, 69-79
23. Recknagel, R. O. (1967), Carbon tetrachloride hepatotoxicity. Pharm. Rev. 19, 145-208
24. Seed, M.; O'Connor, B.; Perombelon, N.; O'Donnell.; Reaveley, D. and Knight, B. L. (1993), The effect of nicotinic acid and acipimox on lypoprotein (a) concentration and turnover. Atherosclerosis. 101, 61-68
25. Siddiqui, M. T. and Siddiqui, M. (1996) Hypolipidemic principles of Cicer arietanum: Biochanin A and Formonometin. Lipids: 11(3), 1975-1978
26. Steinberg, D.; Parthasarathy, S.; Carew, T. E.; Khoo, J. C. and Witztum, J. L. (1989), Beyond Cholesterol: Modification of low-density lipoprotein that increases its atherogenicity. New Engl. J. Med. 320, 915-924
27. Tzeng, S. H.; Ko, W. C.; Ko, F. N. and Teng, C. M. (1991), Inhibition of platelet aggregation by some flavonoids. Thromb. Res. 64, 91-100
28. th ed. Macmillan, New York, 643-660