Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: Evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism

Molecular Genetics and Metabolism

Volumn 89, Issue 1-2, 2006, Pages 64-73

  Chandler, Randy J ^a   Aswani, Vijay ^a   Tsai, Matthew S ^a   Falk, Marni ^b   Wehrli, Natasha ^c   Stabler, Sally ^d   Allen, Robert ^d   Sedensky, Margaret ^e   Kazazian, Haig H ^c   Venditti, Charles P ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Bioinformatics; C. elegans; Cobalamin; Mass spectrometry; Methylmalonic acidemia; Methylmalonyl CoA epimerase; Methylmalonyl CoA mutase; Methylmalonyl CoA racemase; Propionate metabolism; RNA interference

Indexed keywords

COBAMAMIDE; LENTIVIRUS VECTOR; METHYLMALONYL COENZYME A MUTASE; PROPIONIC ACID; PROPIONYL COENZYME A; RNA;

ARTICLE; BIOINFORMATICS; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DELETION MUTANT; ENZYME METABOLISM; FIBROBLAST CULTURE; ISOMERIZATION; MACROMOLECULE; MASS SPECTROMETRY; METAZOON; METHYLMALONIC ACIDEMIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; RNA INTERFERENCE;

ACIDOSIS; ACYL COENZYME A; ALKYL AND ARYL TRANSFERASES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; COBAMIDES; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENETIC COMPLEMENTATION TEST; HUMANS; METHYLMALONIC ACID; METHYLMALONYL-COA MUTASE; RACEMASES AND EPIMERASES; RNA INTERFERENCE; TRANSFECTION;

CAENORHABDITIS ELEGANS; MAMMALIA; METAZOA;

EID: 33746982979     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2006.06.001     Document Type: Article

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