Acute toxicity of organophosphorous pesticide diazinon and its effects on behavior and some hematological parameters of fingerling European catfish (Silurus glanis L.)

Pesticide Biochemistry and Physiology

Volumn 86, Issue 2, 2006, Pages 99-105

  Köprücü, Sibel Şimşek ^a   Köprücü, Kenan ^a   Ural, Mevlüt Şener ^a   Ispir, Ünal ^a   Pala, Murat ^b  

^a FIRAT UNIVERSITY   (Turkey)

^b GENERAL DIRECTORATE OF STATE HYDRAULIC WORKS   (Turkey)

Author keywords

Acute toxicity; Behavior; Diazinon; European catfish; Hematological parameters; Organophosphorous pesticide; Silurus glanis

Indexed keywords

PISCES; SILURUS GLANIS;

EID: 33746958907     PISSN: 00483575     EISSN: 10959939     Source Type: Journal    
DOI: 10.1016/j.pestbp.2006.02.001     Document Type: Article

References (48)

1. URL 1. Available from: .
2. Kuivila K.M., and Foe C.G. Concentrations, transport and biological effects of dormant spray pesticides in the San Francisco Estuary, California. Environ. Toxicol. Chem. 14 (1995) 1141-1150
3. M.J. Ferrari, S.W. Ator, J.D. Blomquist, J.E. Dysart, Pesticides in surface water of the Mid-Atlantic Region, U.S. Geological Survey Water-Resources Investigations Report 9797-4280, 1997, 20 p.
4. Burkepile D.E., Moore M.T., and Holland M.M. The susceptibility of five nontarget organisms to aqueous diazinon exposure. Bull. Environ. Contam. Toxicol. 64 (2000) 114-121
5. Oh H.S., Lee S.K., Kim Y.H., and Roh J.K. Mechanism of selective toxicity of diazinon to killifish (Oryzias latipes) and loach (Misgurnus anguillicaudatus). Aquat. Toxicol. Risk Asses. 14 (1991) 343-353
6. Sancho E., Ferrando M.D., Andreau E., and Gamon M. Bioconcentration and excretion of diazinon by eel. Bull. Environ. Contam. Toxicol. 50 (1993) 578-585
7. Office of Pesticide Programs, Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database). Environmental Fate and Effects Division, US EPA, Washington D.C., 2000.
8. Keizer J., DeAgostino G., and Vittozzi I. The importance of biotransformation in the toxicity of xenobiotics to fish. 1: Toxicity and bioaccumulation of diazinon in guppy (Poecilia reticulata) and zebra fish (Brachydanio rerio). Aquat. Toxicol. 21 (1991) 239-254
9. Pesando D., Huitorel P., Dolcini V., Angelini C., Guidetti P., and Falugi C. Biological targets of neurotoxic pesticides analysed by alteration of developmental events in the Mediterranean Sea urchin, Paracentrotus lividus. Mar. Environ. Res. 55 (2003) 39-57
10. Dutta H.M., and Arends D. Effects of endosulfan on brain acetylcholinesterase activity in juvenile bluegill sunfish. Environ. Res. 91 (2003) 157-162
11. Hamm J.T., and Hinton D.E. The role of development and duration of exposure to the embryotoxicity of diazinon. Aquat. Toxicol. 48 4 (2000) 403-418
12. Wall S.B. Sublethal effects of cadmium and diazinon on reproduction and larval behavior in zebrafish. Diss. Abst. Inter. Part B. Sci. Eng. 60 (2000) 3829
13. Dutta H.M., and Meijer H.J.M. Sublethal effects of diazinon on the structure of the testis of bluegill, Lepomis macrochirus: a microscopic analysis. Environ. Pollut. 125 (2003) 355-360
14. Aydin R., and Köprücü K. Acute toxicity of diazinon on the common carp (Cyprinus carpio L.) embryos and larvae. Pest. Biochem. Physiol. 82 3 (2005) 220-225
15. Dutta H.M., Munshi J.S.D., Dutta G.R., Singh N.K., Adhikari S., and Richmonds C.R. Age related differences in the inhibition of brain acetylcholinesterase activity of Heteropneustes fossillis (Bloch) by malathion. Comp. Biochem. Physiol. A 111 2 (1995) 331-334
16. Dutta H.M., and Arends D.A. Effects of endosulfan on brain acetylcholinesterase activity in juvenile bluegill sunfish. Environ. Res. 91 (2003) 157-162
17. Dutta H.M., Marcelino J., and Richmonds C. Brain acetylcholinesterase activity and optomotor behavior in bluegills, Lepomis macrochirus, exposed to five different concentrations of diazinon. Arch. Int. Physiol. Biochim. Biophys. 100 (1992) 331-334
18. Dutta H.M., and Maxwell L.B. Histological examination of sublethal effects of diazinon on ovary of bluegill, Lepomis macrochirus. Environ. Pollut. 121 (2003) 95-102
19. Maxwell L.B., and Dutta H.M. Diazinon-induced endocrine disruption in bluegill sunfish, Lepomis macrochirus. Ecotoxicol. Environ. Saf. 60 (2005) 21-27
20. Svobodova S. Changes in the blood picture of the carp intoxicated with organophosphate pesticides. Acta Vet. Brno 44 (1975) 49-52
21. Benarji G., and Rajendranath T. Hematological changes induced by an organophosphorus insecticide in a freshwater fish Clarias batrachus (Linnaeus). Trop. Freshwater Biol. 2 (1990) 197-202
22. Sampath K., Velammal S., Kennedy I.J., and James R. Hematological changes and their recovery in Oreochromis mossambicus as an function of exposure period and sublethal levels of ekalux. Acta Hydrobiol. 35 (1993) 73-83
23. Singh N., and Srivastava A.K. Formothion induced hematological changes in the freshwater Indian cathfish, Heteropneustes fossilis. J. Ecotoxicol Environ. Monit. 4 (1994) 137-140
24. Nath R., and Banerjee V. Effect of pesticides methylparathion and cypermethrin on the air-breathing fish Heteropneustes fossilis. Environ. Ecol. 14 (1996) 163-165
25. Khattak I.U., and Hafeez M.A. Effect of malathion on blood parameters of the fish, Cyprinion wabsoni. Pak. J. Zool. 28 (1996) 45-49
26. Tavares D.M., Martines M.L., and Nascimento K.S. Evaluation of the hematological parameters in Piaractus mesopotamicus Holmberg (Osteichthyes, Characidae) with Argulus sp. (Crustacea, Branchiura) infestation and treatment with organophosphate. Rev. Bras. Zool. 16 (1999) 5553-5555
27. Anees M.A. Hematological abnormalities in a freshwater teleost, Channa punctatus (Bloh) exposed to sublethal and chronic levels of three organophosphorus insecticides. Int. J. Ecol. Environ. Sci. 4 (1978) 53-60
28. Svoboda M., Luskova V., Drastichova J., and Zlabek V. The effect of diazinon on hematological indices of common carp (Cyprinus carpio L.). Acta Vet. Brno. 70 (2001) 457-465
29. Linhart O., Setch L., Svarc J., Rodina M., Audebert J.P., Grecu J., and Billard R. The culture of the European catfish, Silurus glanis, in the Czech Republic and in France. Aquat. Living Resour. 15 (2002) 139-144
30. DIE (State Institute of Statistics), Turkey's Statistical Yearbook. Ankara, 2004, 391 p.
31. R. Geldiay, S. Bali{dotless}k, Turkey's Freshwater Fishes, second ed., Izmir, 1996, 552 p. (In Trukish.).
32. APHA (American Public Health Association), Standard Methods for the Examination of Water and Wastewater, sixteenth ed., Washington, DC, 1985, 1268 p.
33. Smith G.L., and Hatting J. Hematological assessment of generally used freshwater fish blood anticoagulant. J. Fish Biol. 17 (1980) 330-341
34. Jain N.C. Essentials of Veterinary Hematology (1993), Lea and Febiger, Philadelphia 417 p.
35. Giddings J.M., Biever R.C., Annunziato M.F., and Hosmer A.J. Effects of diazinon on large outdoor pond microcosme. Environ. Toxicol. Chem. 15 (1996) 618-629
36. Sancho E., Ferrando M.D., Gamon M., and Andreu-Moliner E. An approach to the diazinon toxicity in the European eel: bioaccumulation studies. Sci. Total Environ. (1993) 461-468
37. Lakota S., Razska A., Utracki T., and Chmiel Z. Side-effect of deltamethrin and cypermethrin in the environment of water biocenoses. Organika 71 (1989) 71-77
38. Viran R., Erkoç F.Ü., Polat H., and Koçak Ö. Investigation of acute toxicity of deltamethrin on guppies (Poecilia reticulata). Ecotoxicol. Environ. Saf. 55 (2003) 82-85
39. Saha S., and Kaviraj A. Acute toxicity synthetic pyrethroid cypermethrin freshwater catfish, Heteropneustes fossilis (Block). Int. J. Toxicol. 22 (2003) 325-328
40. Çalta M., and Ural M.Ş. Acute toxicity of the synthetic pyrethroid deltamethrin to young mirror carp, Cyprinus carpio. Fresenius Environ. Bull. 13 11a (2004) 1179-1183
41. Walker C.H., and Thompson H.M. Phylogenetic distribution of cholinesterase and related esterases. In: Mineau P. (Ed). Cholinesterase-Inhibiting Insecticides-Their Impact On Wildlife And The Environment (1991), Elsevier Science Publishers, Amsterdam 1-18
42. Scherer E., and Harrison S.E. The optomotor response test. In: Scherer E. (Ed). Toxicity Tests for Freshwater Organisms Vol. 44 (1979), Canadian Special Publication of Fisheries and Aquatic Sciences, NRC Research Press, Ottawa 179
43. Pan G., and Dutta H.M. The inhibition of brain acetylcholinesterase activity of juvenile largemouth bass, Micropterus salmoides by sublethal concentrations of diazinon. Environ. Res. Sect. A 79 (1998) 133-137
44. Benarji G., and Rajendranath T. Hematological changes induced by an organophosphorous insecticide in a freshwater fish Clarias batrachus (Linnaeus). Trop. Freshwater Biol. 2 (1990) 197-202
45. Singh N.N., and Srivastava A.K. Formothion induced hematological changes in the freshwater Indian catfish, Heteropneustes fossilis. J. Ecotoxicol. Environ. Monit. 4 (1994) 137-140
46. Khattak I.U.D., and Hafeez M.A. Effect of malathion on blood parameters of the fish, Cyprinion watsoni. Pak. J. Zool. 28 (1996) 45-49
47. Tavares D.M., Martins M.L., and Nascimento K.S. Evalution of the hematological parameters in Piaractus mesopotamicus Holmberg (Osteichthyes, Characidae) with Argulus sp. (Crustacea, Brachiura) infestation and treatment with organophosphate. Rev. Bras. Zool. 16 (1999) 553-555
48. Morgan D.P., Stockdale E.M., Roberts R.J., and Walter H.W. Anemia associated with exposure to lindane. Arch. Environ. Health 35 (1980) 307-310