Percutaneous endocardial injection of erythropoietin: Assessment of cardioprotection by electromechanical mapping

European Journal of Heart Failure

Volumn 8, Issue 5, 2006, Pages 443-450

  Krause, Korff T ^a   Jaquet, Kai ^a   Geidel, Stephan ^a   Schneider, Carsten ^a   Mandel, Christina ^b   Stoll, Hans Peter ^c   Hertting, Klaus ^a   Harle, Tobias ^a   Kuck, Karl Heinz ^a  

^a DEPARTMENT OF CARDIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Clinical Research   (Belgium)

Author keywords

Cardioprotection; Electromechanical mapping; Percutaneous endocardial injection

Indexed keywords

ERYTHROPOIETIN; PLACEBO;

ANGIOCARDIOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATHETER; CELL PROTECTION; CONTROLLED STUDY; DISEASE COURSE; ECHOCARDIOGRAPHY; ELECTRIC POTENTIAL; HEART EJECTION FRACTION; HEART LEFT VENTRICLE; HEART MUSCLE; HEART MUSCLE FIBROSIS; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE WALL; HISTOLOGY; INJECTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SWINE; TISSUE INJURY;

ANIMALS; CHRONIC DISEASE; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; ENDOCARDIUM; ERYTHROPOIETIN; IMAGE PROCESSING, COMPUTER-ASSISTED; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL STUNNING; SWINE;

EID: 33746957324     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2005.10.017     Document Type: Article

References (31)

1. Brines M.L., Ghezzi P., Keenan S., et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A 97 (2000) 10526-10531
2. Ehrenreich H., Hasselblatt M., Dembowski C., et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 8 (2002) 495-505
3. Wright G.L., Hanlon P., Amin K., Steenbergen C., Murphy E., and Arcasoy M.O. Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. FASEB J 18 (2004) 1031-1033 [Electronic publication 2004 Apr 01]
4. Parsa C.J., Kim J., Riel R.U., et al. Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem 279 (2004) 20655-20662 [Electronic publication 2004 Mar 11]
5. Ogilvie M., Yu X., Nicolas-Metral V., et al. Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts. J Biol Chem 275 (2000) 39754-39761
6. Wojchowski D.M., Gregory R.C., Miller C.P., Pandit A.K., and Pircher T.J. Signal transduction in the erythropoietin receptor system. Exp Cell Res 253 (1999) 143-156
7. Tramontano A.F., Muniyappa R., Black A.D., et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun 308 (2003) 990-994
8. Bolli R., Bhatti Z.A., Tang X.L., et al. Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide. Circ Res 81 (1997) 42-52
9. Bahlmann F.H., De Groot K., Spandau J.M., et al. Erythropoietin regulates endothelial progenitor cells. Blood 103 (2004) 921-926
10. Jaquet K., Krause K., Tawakol-Khodai M., Geidel S., and Kuck K.H. Erythropoietin and VEGF exhibit equal angiogenic potential. Microvasc Res 64 (2002) 326-333
11. Parsa C.J., Matsumoto A., Kim J., et al. A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest 112 (2003) 999-1007
12. Moon C., Krawczyk M., Ahn D., et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci U S A 100 (2003) 11612-11617 [Electronic publication 2003 Sep 19]
13. Kajstura J., Cheng W., Reiss K., et al. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 7 (1996) 86-107
14. Elsasser A., Vogt A.M., Nef H., et al. Human hibernating myocardium is jeopardized by apoptotic and autophagic cell death. J Am Coll Cardiol 43 (2004) 2191-2199
15. Ben-Haim S.A., Osadchy D., Schuster I., Gepstein L., Hayam G., and Josephson M.E. Nonfluoroscopic, in vivo navigation and mapping technology. Nat Med 2 (1996) 1393-1395
16. Gepstein L., Hayam G., and Ben-Haim S.A. A novel method for nonfluoroscopic catheter-based electroanatomical mapping of the heart. In vitro and in vivo accuracy results. Circulation 9 (1997) 1611-1622
17. Botker H.E., Lassen J.F., Hermansen F., et al. Electromechanical mapping for detection of myocardial viability in patients with ischemic cardiomyopathy. Circulation 103 (2001) 1631-1637
18. Wiggers H., Botker H.E., Sogaard P., et al. Electromechanical mapping versus positron emission tomography and single photon emission computed tomography for the detection of myocardial viability in patients with ischemic cardiomyopathy. Am Coll Cardiol 41 (2003) 843-848
19. Hsia H.H., Callans D.J., and Marchlinski F.E. Characterization of endocardial electrophysiological substrate in patients with nonischemic cardiomyopathy and monomorphic ventricular tachycardia. Circulation 108 (2003) 704-710 [Electronic publication 2003 Jul 28]
20. Hughes G.C., Post M.J., Simons M., and Annex B.H. Translational physiology: porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis. J Appl Physiol 94 (2003) 1689-1701
21. Elsasser A., Schlepper M., Zimmermann R., et al. The extracellular matrix in hibernating myocardium-a significant factor causing structural defects and cardiac dysfunction. Mol Cell Biochem 186 (1998) 147-158
22. Depre C., Vanoverschelde J.L., Gerber B., Borgers M., Melin J.A., and Dion R. Correlation of functional recovery with myocardial blood flow, glucose uptake, and morphologic features in patients with chronic left ventricular ischemic dysfunction undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 113 (1997) 371-378
23. Depre C., Vanoverschelde J.L., Melin J.A., et al. Structural and metabolic correlates of the reversibility of chronic left ventricular ischemic dysfunction in humans. Am J Physiol 268 (1995) H1265-H1275
24. Shi Y., Baker J.E., Zhang C., Tweddell J.S., Su J., and Pritchard Jr. K.A. Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. Circ Res 91 (2002) 300-306
25. Rafiee P., Shi Y., Kong X., et al. Activation of protein kinases in chronically hypoxic infant human and rabbit hearts: role in cardioprotection. Circulation 106 (2002) 239-245
26. Lim H., Fallavollita J.A., Hard R., Kerr C.W., and Canty Jr. JM. Profound apoptosis-mediated regional myocyte loss and compensatory hypertrophy in pigs with hibernating myocardium. Circulation 100 (1999) 2380-2386
27. Depre C., Kim S.J., John A.S., et al. Program of cell survival underlying human and experimental hibernating myocardium. Circ Res 95 (2004) 433-440
28. Elsasser A., Decker E., Kostin S., et al. A self-perpetuating vicious cycle of tissue damage in human hibernating myocardium. Mol Cell Biochem 213 (2000) 17-28
29. Keck A., Hertting K., Schwartz Y., et al. Electromechanical mapping for determination of myocardial contractility and viability. A comparison with echocardiography, myocardial single-photon emission computed tomography, and positron emission tomography. J Am Coll Cardiol 8 (2002) 1067-1074
30. Hebert P.C., Wells G., Blajchman M., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340 (1999) 409-417
31. Besarab A., Bolton W.K., Browne J.K., et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and EPOetin. N Engl J Med 339 (1998) 584-590