Mice carrying null mutations in the insulin and insulin receptor genes

Experimental and Clinical Endocrinology and Diabetes

Volumn 104, Issue , 1996, Pages 2-3

  Joshi, Rajiv L ^a   Deltour, Louise ^a   Duvillié, Bertrand ^a   Cordonnier, Nathalie ^a   Lamothe, Betty ^a   Bucchini, Danielle ^a   Jami, Jacques ^a  

^a INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746948969     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1211488     Document Type: Article

References (7)

1. Accili D, Drago J, Lee EJ, Johnson MD, Cool MH, Salvatore P, Asico LD, Jose PA, Taylor SI and Wesphal H. Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nature Genetics, 1996, 12: 106-109
2. De Chiara TM, Efstratiadis A and Robertson EJ. A growth-deficient phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature, 1990, 345: 78-80
3. Deltour L, Leduque P, Blume N, Madsen O, Dubois P, Jami J, and Bucchini D. Differential expression of the two non-allelic proinsulin genes in the developing mouse embryo. Proc Natl Acad Sci USA, 1992, 90: 527-53
4. Deltour L, Montagutelli X, Guénet JL, Jami J and Paldi A. Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2. Dev Biol, 1995, 168: 686-688
5. Jonsson J, Carlsson L, Edlund T and Edlund H. Insulinpromoter-factor 1 is required for pancreas development in mice. Nature, 1994, 371: 606-609
6. Joshi RL, Lamothe B, Cordonnier N, Mesbah K, Monthioux E, Jami J, Bucchini D. Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality. EMBO J 1996 (in press)
7. Liu JP, Baker J, Perkins AS, Robertson EJ and Efstratiadis A. Mice carrying null mutations of the genes encoding Insulin-like Growth Factor I (Igf-1) and Type 1 IGF Receptor (Igflr). Cell, 1993, 75: 59-72