Chimerism in a child with severe combined immunodeficiency: A case report

Pediatric Transplantation

Volumn 10, Issue 6, 2006, Pages 744-746

  Aureli, Anna ^a,c   Piancatelli, Daniela ^a   Monaco, Palmina I ^a   Ozzella, Giuseppina ^a   Canossi, Angelica ^a   Piazza, Antonina ^a   Isacchi, Giancarlo ^b   Caniglia, Maurizio ^b   Adorno, Domenico ^a  

^a CNR Institute for Organ Transplantation and Immunocytology   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^c CNR Istituto Per I Trapianti d'Organo e l'Immunocitologia   (Italy)

Author keywords

Blood chimerism; Microsatellite analysis SBT; SCID

Indexed keywords

ARTICLE; B LYMPHOCYTE; CASE REPORT; CELL FUNCTION; CHIMERA; COMBINED IMMUNODEFICIENCY; DISEASE SEVERITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INFANT; MALE; T LYMPHOCYTE;

ALLELES; CHIMERISM; HUMANS; INFANT; MALE; POLYMERASE CHAIN REACTION; SEVERE COMBINED IMMUNODEFICIENCY;

EID: 33746932061     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2006.00568.x     Document Type: Article

References (11)

1. ROSEN FS, COOPER MD, WEDGWOOD JP. The primary immunodeficiencies. N Engl J Med 1995: 333: 431-440.
2. KADOWAKI JI, ZUELZER WW, BROUGH AJ, THOMPSON RL, WOOLEY PV, GRUBER D. XX/XY lymphoid chimerism in congenital immunological deficiency syndrome with thymic alymphoplasia. Lancet 1965: 2: 1152-1155.
3. POLLACK MS, KIRKPATRICK D, KAPOOR N, DUPONT B, O'REILLY RJ. Identification of intrauterine-derived maternal T-cells in four patients with severe combined immunodeficiency. N Engl J Med 1982: 11: 662-666.
4. FLOMBERG N, DUPONT B, O'REILLY RJ, HAYWARD A, POLLACK M. The use of T cell culture techniques to establish the presence of an intrauterine derived maternal T-cell graft in a patient with severe combined immunodeficiency (SCID). Transplantation 1993: 36: 733-735.
5. CONLEY ME, NOWELL PC, HENLE G, DOUGLAS SD. XX T-cells and XY B-cells in two patients with severe combined immune deficiency. Clin Immunol Immunopathol 1984: 31: 87-95.
6. GEHA R, REINHERZ E. Identification of maternal T and B lymphocytes in uncomplicated severe combined immunodeficiency by HLA typing of subpopulations of T-cells separated by the fluorescence-activated cell sorter and of Epstein-Barr virus derived B cell lines. J Immunol 1983: 130: 2493-2530.
7. PINDOLIA K, JANAKIRAMAN N, KASTEN-SPORTES C, et al. Enhanced assessment of allogeneic bone marrow transplant engraftment using automated fluorescent-based typing. Bone Marrow Transplant 1999: 24: 1235-1241.
8. LO Y, ESF L, WATSON N, et al. Two-way cell traffic between mother and fetus: biologic and clinical implications. Blood 1996: 88: 4390-4395.
9. LO Y, LAU T, CHAN L, LEUNG T, CHANG A. Quantitative analysis of the bi-directional fetomaternal transfer of nucleated cells and plasma DNA. Clin Chem 2000: 46: 1301-1309.
10. SCARADAVOU A, CARRIER C, MOLLEN N, STEVENS C, RUBINSTEIN P. Detection of maternal DNA in placental/umbilical cord blood by locus-specific amplification of the noninherited maternal HLA gene. Blood 1996: 88: 1494-1500.
11. MULLER MS, EGE M, POTTHARST A, SCHULZ AS, SCHWARZ K, FRIEDRICH W. Transplacentally acquired maternal T lymphocytes in severe combined immunodeficiency: a study of 121 patients. Blood 2001: 98: 1847-1851.